8CEE
| Rnase R bound to a 30S degradation intermediate (State I - head-turning) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | 登録日 | 2023-02-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
|
|
8CDV
| Rnase R bound to a 30S degradation intermediate (state II) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | 登録日 | 2023-02-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.73 Å) | 主引用文献 | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
|
|
8CDU
| Rnase R bound to a 30S degradation intermediate (main state) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | 登録日 | 2023-02-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
|
|
8QCQ
| B. subtilis ApdA-stalled ribosomal complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Morici, M, Wilson, D.N. | 登録日 | 2023-08-28 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity. Nat Commun, 15, 2024
|
|
8QOA
| Structure of SecM-stalled Escherichia coli 70S ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ... | 著者 | Gersteuer, F, Morici, M, Wilson, D.N. | 登録日 | 2023-09-28 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome. Nat Commun, 15, 2024
|
|
8QBT
| E. coli ApdP-stalled ribosomal complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | 著者 | Morici, M, Wilson, D.N. | 登録日 | 2023-08-25 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity. Nat Commun, 15, 2024
|
|
8AP4
| |
8ANA
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the 50S ribosomal subunit | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, 50S ribosomal protein L13, ... | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | 登録日 | 2022-08-05 | 公開日 | 2023-03-08 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
|
|
3J9Y
| Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Arenz, S, Nguyen, F, Beckmann, R, Wilson, D.N. | 登録日 | 2015-03-23 | 公開日 | 2015-04-15 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3J9W
| Cryo-EM structure of the Bacillus subtilis MifM-stalled ribosome complex | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein bS16, ... | 著者 | Sohmen, D, Chiba, S, Shimokawa-Chiba, N, Innis, C.A, Berninghausen, O, Beckmann, R, Ito, K, Wilson, D.N. | 登録日 | 2015-03-16 | 公開日 | 2015-04-29 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling. Nat Commun, 6, 2015
|
|
5FDV
| Crystal structure of the Pyrrhocoricin antimicrobial peptide bound to the Thermus thermophilus 70S ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A. | 登録日 | 2015-12-16 | 公開日 | 2016-01-27 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. Nucleic Acids Res., 44, 2016
|
|
3J7Z
| Structure of the E. coli 50S subunit with ErmCL nascent chain | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Arenz, S, Meydan, S, Starosta, A.L, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Wilson, D.N. | 登録日 | 2014-08-27 | 公開日 | 2014-10-22 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation. Mol.Cell, 56, 2014
|
|
8AM9
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome | 分子名称: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | 登録日 | 2022-08-03 | 公開日 | 2023-03-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
|
|
8AKN
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome | 分子名称: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | 登録日 | 2022-07-30 | 公開日 | 2023-03-08 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
|
|
8A63
| Cryo-EM structure of Listeria monocytogenes 50S ribosomal subunit. | 分子名称: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ... | 著者 | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2022-06-16 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8A5I
| Cryo-EM structure of Lincomycin bound to the Listeria monocytogenes 50S ribosomal subunit. | 分子名称: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ... | 著者 | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2022-06-15 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8A57
| Cryo-EM structure of HflXr bound to the Listeria monocytogenes 50S ribosomal subunit. | 分子名称: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L11, ... | 著者 | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2022-06-14 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8BUU
| ARE-ABCF VmlR2 bound to a 70S ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Wilson, D.N. | 登録日 | 2022-11-30 | 公開日 | 2023-04-05 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR. Nucleic Acids Res., 51, 2023
|
|
8B7Y
| Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Koller, T.O, Graf, M, Wilson, D.N. | 登録日 | 2022-10-03 | 公開日 | 2023-01-25 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. J.Am.Chem.Soc., 145, 2023
|
|
3J5L
| Structure of the E. coli 50S subunit with ErmBL nascent chain | 分子名称: | 23S ribsomal RNA, 5'-R(*CP*(MA6))-3', 5'-R(*CP*CP*A)-3', ... | 著者 | Arenz, S, Ramu, H, Gupta, P, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Mankin, A.S, Wilson, D.N. | 登録日 | 2013-10-23 | 公開日 | 2014-03-26 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. Nat Commun, 5, 2014
|
|
3J25
| Structural basis for TetM-mediated tetracycline resistance | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Tetracycline resistance protein tetM | 著者 | Doenhoefer, A, Franckenberg, S, Wickles, S, Berninghausen, O, Beckmann, R, Wilson, D.N. | 登録日 | 2012-08-22 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structural basis for TetM-mediated tetracycline resistance. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2ZJP
| Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans | 分子名称: | 4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ... | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | 登録日 | 2008-03-07 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin. Mol.Cell, 30, 2008
|
|
2ZJR
| Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | 登録日 | 2008-03-08 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
|
|
2ZJQ
| Interaction of L7 with L11 induced by Microccocin binding to the Deinococcus radiodurans 50S subunit | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | 登録日 | 2008-03-08 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
|
|
7JQL
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | 登録日 | 2020-08-11 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
|
|