8H6P
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![BU of 8h6p by Molmil](/molmil-images/mine/8h6p) | Complex structure of CDK2/Cyclin E1 and a potent, selective macrocyclic inhibitor | 分子名称: | (7S,10R)-11-oxa-2,4,5,13,17,23-hexaazatetracyclo[17.3.1.1~3,6~.1~7,10~]pentacosa-1(23),3(25),5,19,21-pentaene-12,18-dione, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | 著者 | Ren, X. | 登録日 | 2022-10-18 | 公開日 | 2023-02-22 | 最終更新日 | 2023-03-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. Acs Med.Chem.Lett., 14, 2023
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3HW3
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![BU of 3hw3 by Molmil](/molmil-images/mine/3hw3) | The crystal structure of avian influenza virus PA_N in complex with UMP | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE | 著者 | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | 登録日 | 2009-06-17 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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3HW5
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![BU of 3hw5 by Molmil](/molmil-images/mine/3hw5) | crystal structure of avian influenza virus PA_N in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Polymerase acidic protein | 著者 | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Liang, S, Rao, Z. | 登録日 | 2009-06-17 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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3HW6
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![BU of 3hw6 by Molmil](/molmil-images/mine/3hw6) | Crystal structure of avian influenza virus PA_N in complex with Mn | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein | 著者 | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | 登録日 | 2009-06-17 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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6FBV
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![BU of 6fbv by Molmil](/molmil-images/mine/6fbv) | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Das, K, Lin, W, Ebright, E. | 登録日 | 2017-12-19 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
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2MYP
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2MYT
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5YJ8
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2L0K
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![BU of 2l0k by Molmil](/molmil-images/mine/2l0k) | NMR solution structure of a transcription factor SpoIIID in complex with DNA | 分子名称: | Stage III sporulation protein D | 著者 | Chen, B, Himes, P, Lu, Z, Liu, A, Yan, H, Kroos, L. | 登録日 | 2010-07-08 | 公開日 | 2011-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Novel Mode of DNA Binding by Bacterial Transcription Factor SpoIIID To be Published
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3HW4
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![BU of 3hw4 by Molmil](/molmil-images/mine/3hw4) | Crystal structure of avian influenza A virus in complex with TMP | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE | 著者 | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | 登録日 | 2009-06-17 | 公開日 | 2009-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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2MYN
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![BU of 2myn by Molmil](/molmil-images/mine/2myn) | An arsenate reductase in reduced state | 分子名称: | Glutaredoxin arsenate reductase | 著者 | Jin, C, Yu, C, Hu, C, Hu, Y. | 登録日 | 2015-01-30 | 公開日 | 2015-08-05 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction. J.Biol.Chem., 290, 2015
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2MYU
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![BU of 2myu by Molmil](/molmil-images/mine/2myu) | An arsenate reductase in oxidized state | 分子名称: | Glutaredoxin arsenate reductase | 著者 | Jin, C, Hu, C, Hu, Y. | 登録日 | 2015-01-30 | 公開日 | 2015-08-05 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction. J.Biol.Chem., 290, 2015
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8WXE
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![BU of 8wxe by Molmil](/molmil-images/mine/8wxe) | Vgamma5Vdelta1 EH TCR-CD3 complex | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-28 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
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8YC0
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![BU of 8yc0 by Molmil](/molmil-images/mine/8yc0) | T cell receptor V delta2 V gamma9 in GDN | 分子名称: | CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2024-02-17 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
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4EGT
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![BU of 4egt by Molmil](/molmil-images/mine/4egt) | Crystal structure of major capsid protein P domain from rabbit hemorrhagic disease virus | 分子名称: | Major capsid protein VP60 | 著者 | Wang, X, Xu, F, Zhang, K, Zhai, Y, Sun, F. | 登録日 | 2012-04-01 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. Plos Pathog., 9, 2013
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6U84
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4E0R
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![BU of 4e0r by Molmil](/molmil-images/mine/4e0r) | Structure of the chicken MHC class I molecule BF2*0401 | 分子名称: | 8-MERIC PEPTIDE (FUS/TLS), Beta-2 microglobulin, MHC class I alpha chain 2 | 著者 | Zhang, J, Chen, Y, Qi, J, Gao, F, Kaufman, J, Xia, C, Gao, G.F. | 登録日 | 2012-03-05 | 公開日 | 2012-11-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. J.Immunol., 189, 2012
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8TBF
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![BU of 8tbf by Molmil](/molmil-images/mine/8tbf) | Tricomplex of RMC-7977, KRAS WT, and CypA | 分子名称: | (1R,5S,6r)-N-[(1P,7S,9S,13S,20M)-20-{5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]pyridin-3-yl}-21-ethyl-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide, 1,2-ETHANEDIOL, GTPase KRas, ... | 著者 | Tomlinson, A.C.A, Chen, A, Knox, J.E, Yano, J.K. | 登録日 | 2023-06-28 | 公開日 | 2024-02-07 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature, 629, 2024
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6U86
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6U8A
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6U88
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8K0D
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8K0C
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2PZ9
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![BU of 2pz9 by Molmil](/molmil-images/mine/2pz9) | Crystal structure of putative transcriptional regulator SCO4942 from Streptomyces coelicolor | 分子名称: | Putative regulatory protein, SULFATE ION | 著者 | Filippova, E.V, Chruszcz, M, Xu, X, Zheng, H, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-05-17 | 公開日 | 2007-06-19 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | In situ proteolysis for protein crystallization and structure determination. Nat.Methods, 4, 2007
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1P5Q
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![BU of 1p5q by Molmil](/molmil-images/mine/1p5q) | Crystal Structure of FKBP52 C-terminal Domain | 分子名称: | FK506-binding protein 4, SULFATE ION | 著者 | Wu, B, Li, P, Lou, Z, Shu, C, Ding, Y, Shen, B, Rao, Z. | 登録日 | 2003-04-28 | 公開日 | 2004-06-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | 3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex Proc.Natl.Acad.Sci.USA, 101, 2004
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