7X7W
| The X-ray Crystallographic Structure of D-Psicose 3-epimerase from Clostridia bacterium | 分子名称: | D-PSICOSE 3-EPIMERASE, MANGANESE (II) ION | 著者 | Li, Z.F, Ban, X.F, Xie, X.F, Tian, Y.X, Li, C.M, Gu, Z.B. | 登録日 | 2022-03-10 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | 主引用文献 | Crystal structure of a novel homodimeric D-allulose 3-epimerase from a Clostridia bacterium Acta Crystallogr.,Sect.D, 78, 2022
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7XB5
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7XS4
| Crystal structure of URT1 in complex with AAAU RNA | 分子名称: | RNA (5'-R(*AP*AP*AP*U)-3'), UTP:RNA uridylyltransferase 1 | 著者 | Hu, Q, Zhu, L.R, lv, M.Q, Gong, Q.G. | 登録日 | 2022-05-12 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.846 Å) | 主引用文献 | Molecular mechanism underlying the di-uridylation activity of Arabidopsis TUTase URT1. Nucleic Acids Res., 50, 2022
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7CR2
| human KCNQ2 in complex with retigabine | 分子名称: | Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR7
| human KCNQ2-CaM in complex with retigabine | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR0
| human KCNQ2 in apo state | 分子名称: | Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR3
| human KCNQ2-CaM in apo state | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR4
| human KCNQ2-CaM in complex with ztz240 | 分子名称: | Calmodulin-3, N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7D0Q
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7D0P
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7D0O
| Crystal structure of human HBO1-BRPF2 in apo form | 分子名称: | 1,2-ETHANEDIOL, BRD1 protein, Histone acetyltransferase KAT7, ... | 著者 | Li, W, Ding, J. | 登録日 | 2020-09-11 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | HBO1 is a versatile histone acyltransferase critical for promoter histone acylations. Nucleic Acids Res., 49, 2021
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7D0S
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7D0R
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7BAJ
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7BAK
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7BAL
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7CR1
| human KCNQ2 in complex with ztz240 | 分子名称: | N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7BPK
| Zika virus envelope protein mutant bound to mAb | 分子名称: | Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain | 著者 | Dai, L, Qi, J, Gao, G.F. | 登録日 | 2020-03-23 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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7BQ5
| ZIKV sE bound to mAb Z6 | 分子名称: | Z6 Light Chain, Z6 heavy chain, envelope protein | 著者 | Dai, L, Qi, J, Gao, G.F. | 登録日 | 2020-03-24 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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7FAJ
| CARM1 bound with compound 43 | 分子名称: | Histone-arginine methyltransferase CARM1, N'-[[3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methyl-6-phenylazanyl-pyrimidin-2-yl]phenyl]methyl]-N-methyl-ethane-1,2-diamine | 著者 | Cao, D.Y, Li, J, Xiong, B. | 登録日 | 2021-07-06 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2450726 Å) | 主引用文献 | Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy. J.Med.Chem., 64, 2021
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7FAI
| CARM1 bound with compound 9 | 分子名称: | Histone-arginine methyltransferase CARM1, N'-[[3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methyl-6-(oxan-4-ylamino)pyrimidin-2-yl]phenyl]methyl]-N-methyl-ethane-1,2-diamine | 著者 | Cao, D.Y, Li, J, Xiong, B. | 登録日 | 2021-07-06 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09749269 Å) | 主引用文献 | Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy. J.Med.Chem., 64, 2021
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6CE8
| Crystal structure of fragment 2-(Benzo[d]thiazol-2-yl)acetic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | 分子名称: | (1,3-benzothiazol-2-yl)acetic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | 著者 | Harding, R.J, Halabelian, L, Ferreira de Freitas, R, Ravichandran, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-11 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. J. Med. Chem., 61, 2018
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6CEC
| Crystal structure of fragment 3-(3-Methoxy-2-quinoxalinyl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | 分子名称: | 3-(3-methoxyquinoxalin-2-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | 著者 | Harding, R.J, Halabelian, L, Ferreira de Freitas, R, Franzoni, I, Ravichandran, M, Lautens, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-11 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. J. Med. Chem., 61, 2018
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6CEF
| Crystal structure of fragment 3-(1,3-Benzothiazol-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | 分子名称: | 3-(1,3-benzothiazol-2-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | 著者 | Harding, R.J, Halabelian, L, Ferreira de Freitas, R, Ravichandran, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-11 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. J. Med. Chem., 61, 2018
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6CEA
| Crystal structure of fragment 3-(quinolin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | 分子名称: | 3-(quinolin-2-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | 著者 | Harding, R.J, Halabelian, L, Ferreira de Freitas, R, Ravichandran, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-11 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. J. Med. Chem., 61, 2018
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