4HK5
 
 | | Crystal structure of Cordyceps militaris IDCase in apo form | | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | | 著者 | Xu, S, Zhu, J, Ding, J. | | 登録日 | 2012-10-15 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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5YRN
 | | Structure of RIP2 CARD domain | | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | | 著者 | Wu, B, Gong, Q. | | 登録日 | 2017-11-09 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of RIP2 activation and signaling.
Nat Commun, 9, 2018
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2QE3
 | | Crystal structure of human tl1a extracellular domain | | 分子名称: | CHLORIDE ION, TNF superfamily ligand TL1A | | 著者 | Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-06-22 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
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2P0H
 | | ArhGAP9 PH domain in complex with Ins(1,3,4)P3 | | 分子名称: | (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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2OCA
 | | The crystal structure of T4 UvsW | | 分子名称: | ATP-dependent DNA helicase uvsW | | 著者 | Kerr, I.D, White, S.W. | | 登録日 | 2006-12-20 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystallographic and NMR Analyses of UvsW and UvsW.1 from Bacteriophage T4.
J.Biol.Chem., 282, 2007
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4HK6
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6Y09
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2P0F
 | | ArhGAP9 PH domain in complex with Ins(1,3,5)P3 | | 分子名称: | PHOSPHATE ION, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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2P0D
 | | ArhGAP9 PH domain in complex with Ins(1,4,5)P3 | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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7WK2
 | | SARS-CoV-2 Omicron S-close | | 分子名称: | Spike glycoprotein | | 著者 | Li, J.W, Cong, Y. | | 登録日 | 2022-01-08 | | 公開日 | 2022-01-26 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
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7WVO
 | | SARS-CoV-2 Omicron S-open-2 | | 分子名称: | Spike glycoprotein | | 著者 | Li, J.W, Cong, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-03-02 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
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7WVN
 | | SARS-CoV-2 Omicron S-open | | 分子名称: | Spike glycoprotein | | 著者 | Li, J.W, Cong, Y. | | 登録日 | 2022-02-10 | | 公開日 | 2022-03-02 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron.
Nature, 604, 2022
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2R9C
 | | Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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2R9F
 | | Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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2RJK
 | | Crystal Structure of Human TL1A Extracellular Domain C95S Mutant | | 分子名称: | TNF superfamily ligand TL1A | | 著者 | Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Ramagopal, U.A, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-10-15 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
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4IT7
 | | Crystal structure of Al-CPI | | 分子名称: | CPI | | 著者 | Mei, G.Q, Liu, S.L, Sun, M.Z, Liu, J. | | 登録日 | 2013-01-17 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides.
Plos One, 9, 2014
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2RJL
 | | Crystal structure of human TL1A extracellular domain C95S/C135S mutant | | 分子名称: | TNF superfamily ligand TL1A | | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | | 登録日 | 2007-10-15 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
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4HJW
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7VDL
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7VDH
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2 | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-09-07 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VDM
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7XVQ
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5OOG
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7VUZ
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, state2 | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VV5
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state1 | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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