6ZTR
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![BU of 6ztr by Molmil](/molmil-images/mine/6ztr) | Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | 分子名称: | CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ... | 著者 | Rondeau, J.M, Lehmann, S. | 登録日 | 2020-07-20 | 公開日 | 2021-05-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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3LN4
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![BU of 3ln4 by Molmil](/molmil-images/mine/3ln4) | Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2 | 分子名称: | 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Theodossis, A, Gras, S, Rossjohn, J. | 登録日 | 2010-02-01 | 公開日 | 2010-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | 主引用文献 | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
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5VRN
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![BU of 5vrn by Molmil](/molmil-images/mine/5vrn) | CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333. | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-4-[[5-[4-cyano-2-[(~{E})-hydroxyiminomethyl]phenoxy]-1-oxidanyl-3~{H}-2,1$l^{4}-benzoxaborol-1-yl]oxy]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Abendroth, J, Edwards, T.E, Lorimer, D. | 登録日 | 2017-05-11 | 公開日 | 2018-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA. Life Sci Alliance, 1, 2018
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4BD2
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![BU of 4bd2 by Molmil](/molmil-images/mine/4bd2) | Bax domain swapped dimer in complex with BidBH3 | 分子名称: | APOPTOSIS REGULATOR BAX, BH3-INTERACTING DOMAIN DEATH AGONIST | 著者 | Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M. | 登録日 | 2012-10-04 | 公開日 | 2013-02-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152, 2013
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4BD6
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![BU of 4bd6 by Molmil](/molmil-images/mine/4bd6) | Bax domain swapped dimer in complex with BaxBH3 | 分子名称: | APOPTOSIS REGULATOR BAX | 著者 | Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M. | 登録日 | 2012-10-05 | 公開日 | 2013-02-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152, 2013
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5VRM
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![BU of 5vrm by Molmil](/molmil-images/mine/5vrm) | CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333. | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3-oxidanyl-4-[[1-oxidanyl-6-[4-(trifluoromethyl)phenoxy]-3~{H}-2,1$l^{4}-benzoxaborol-1-yl]oxy]oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Abendroth, J, Edwards, T.E, Lorimer, D. | 登録日 | 2017-05-11 | 公開日 | 2018-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA. Life Sci Alliance, 1, 2018
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5DX0
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![BU of 5dx0 by Molmil](/molmil-images/mine/5dx0) | |
5DXJ
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![BU of 5dxj by Molmil](/molmil-images/mine/5dxj) | Crystal structure of CARM1 and sinefungin | 分子名称: | GLYCEROL, Histone-arginine methyltransferase CARM1, SINEFUNGIN | 著者 | Boriack-Sjodin, P.A. | 登録日 | 2015-09-23 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates. Acs Chem.Biol., 11, 2016
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5DWQ
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![BU of 5dwq by Molmil](/molmil-images/mine/5dwq) | |
5DX8
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![BU of 5dx8 by Molmil](/molmil-images/mine/5dx8) | |
3ZXH
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![BU of 3zxh by Molmil](/molmil-images/mine/3zxh) | |
6J2A
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![BU of 6j2a by Molmil](/molmil-images/mine/6j2a) | The structure of HLA-A*3003/NP44 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, NP44 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-31 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J1W
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![BU of 6j1w by Molmil](/molmil-images/mine/6j1w) | The structure of HLA-A*3001/RT313 | 分子名称: | ALA-ILE-PHE-GLN-SER-SER-MET-THR-LYS, Beta-2-microglobulin, HLA-A*3001 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-29 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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4BD8
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![BU of 4bd8 by Molmil](/molmil-images/mine/4bd8) | Bax domain swapped dimer induced by BimBH3 with CHAPS | 分子名称: | 1,2-ETHANEDIOL, APOPTOSIS REGULATOR BAX, PRASEODYMIUM ION | 著者 | Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M. | 登録日 | 2012-10-05 | 公開日 | 2013-02-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152, 2013
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4BD7
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![BU of 4bd7 by Molmil](/molmil-images/mine/4bd7) | Bax domain swapped dimer induced by octylmaltoside | 分子名称: | APOPTOSIS REGULATOR BAX, CHLORIDE ION, PRASEODYMIUM ION | 著者 | Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M. | 登録日 | 2012-10-05 | 公開日 | 2013-02-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152, 2013
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3LN5
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![BU of 3ln5 by Molmil](/molmil-images/mine/3ln5) | Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase | 分子名称: | 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Theodossis, A, Gras, S, Rossjohn, J. | 登録日 | 2010-02-02 | 公開日 | 2010-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
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1W33
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![BU of 1w33 by Molmil](/molmil-images/mine/1w33) | BbCRASP-1 from Borrelia Burgdorferi | 分子名称: | BBCRASP-1, GLYCEROL | 著者 | Cordes, F.S, Roversi, P, Goodstadt, L, Ponting, C, Kraiczy, P, Skerka, C, Kirschfink, M, Simon, M.M, Brade, V, Zipfel, P, Wallich, R, Lea, S.M. | 登録日 | 2004-07-13 | 公開日 | 2005-02-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A Novel Fold for the Factor H-Binding Protein Bbcrasp-1 of Borrelia Burgdorferi Nat.Struct.Mol.Biol., 12, 2005
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4E44
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![BU of 4e44 by Molmil](/molmil-images/mine/4e44) | |
7PH1
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![BU of 7ph1 by Molmil](/molmil-images/mine/7ph1) | Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | 著者 | Dimos, N, Leppkes, J, Koksch, B, Loll, B. | 登録日 | 2021-08-16 | 公開日 | 2022-03-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment. J.Phys.Chem.B, 126, 2022
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1WCO
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![BU of 1wco by Molmil](/molmil-images/mine/1wco) | The solution structure of the nisin-lipid II complex | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALA-FGA-LYS-DAL-DAL PEPTIDE, ... | 著者 | Hsu, S.-T.D, Breukink, E, Tischenko, E, Lutters, M.A.G, de Kruijff, B, Kaptein, R, Bonvin, A.M.J.J, van Nuland, N.A.J. | 登録日 | 2004-11-19 | 公開日 | 2005-03-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat. Struct. Mol. Biol., 11, 2004
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1O0H
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![BU of 1o0h by Molmil](/molmil-images/mine/1o0h) | Ribonuclease A in complex with 5'-ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ribonuclease pancreatic | 著者 | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | 登録日 | 2003-02-21 | 公開日 | 2003-12-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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1O63
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![BU of 1o63 by Molmil](/molmil-images/mine/1o63) | |
1O6C
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![BU of 1o6c by Molmil](/molmil-images/mine/1o6c) | |
4E45
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![BU of 4e45 by Molmil](/molmil-images/mine/4e45) | Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM | 分子名称: | Centromere protein S, Centromere protein X, Fanconi anemia group M protein, ... | 著者 | Fox III, D, Zhao, Y, Yang, W, Weidong, W. | 登録日 | 2012-03-12 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA To be Published
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3IOP
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![BU of 3iop by Molmil](/molmil-images/mine/3iop) | PDK-1 in complex with the inhibitor Compound-8i | 分子名称: | 2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine, 3-phosphoinositide-dependent protein kinase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-14 | 公開日 | 2010-02-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur.J.Med.Chem., 45, 2010
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