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5E8Y
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TGF-BETA RECEPTOR TYPE 2 KINASE DOMAIN (E431A,R433A,E485A,K488A,R493A,R495A) IN COMPLEX WITH STAUROSPORINE
分子名称: STAUROSPORINE, TGF-beta receptor type-2
著者Sheriff, S.
登録日2015-10-14
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of apo and inhibitor-bound TGF beta R2 kinase domain: insights into TGF beta R isoform selectivity.
Acta Crystallogr D Struct Biol, 72, 2016
7X08
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BU of 7x08 by Molmil
S protein of SARS-CoV-2 in complex with 2G1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
著者Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
登録日2022-02-21
公開日2022-03-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
7Y8O
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Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole
分子名称: 2-[2,5-bis(fluoranyl)phenyl]pyrrolidine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SciR
著者Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T.
登録日2022-06-24
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(3-fluorophenyl)-3,4-dihydro-2H-pyrrole
to be published
4OPN
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BU of 4opn by Molmil
Crystal structure of mouse glyoxalase I complexed with mAH
分子名称: L-gamma-glutamyl-N-(3-ethynylphenyl)-N-hydroxy-L-glutaminylglycine, Lactoylglutathione lyase, ZINC ION
著者Zhai, J, Zhang, L, Yuan, M, Zhang, H.
登録日2014-02-06
公開日2015-02-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reversible Inhibition of Glyoxalase I: Synthesis and Activity Evaluation
To be Published
6AKW
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BU of 6akw by Molmil
Crystal structure of RNA dioxygenase bound with an inhibitor
分子名称: 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO
著者Yang, C.-G, Huang, Y, Gan, J.
登録日2018-09-04
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Cancer Cell, 35, 2019
8ITF
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BU of 8itf by Molmil
Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-22
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
6FZ4
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BU of 6fz4 by Molmil
Structure of GluK1 ligand-binding domain in complex with N-(7-fluoro-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)-2-hydroxybenzamide at 1.85 A resolution
分子名称: CHLORIDE ION, GLYCEROL, Glutamate receptor ionotropic, ...
著者Kastrup, J.S, Frydenvang, K, Mollerud, S.
登録日2018-03-14
公開日2019-01-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
Acs Chem Neurosci, 10, 2019
7WL9
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BU of 7wl9 by Molmil
Mouse Pendrin in chloride and bicarbonate in asymmetric state
分子名称: CHLORIDE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL2
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BU of 7wl2 by Molmil
Mouse Pendrin in bicarbonate and iodide buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLA
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BU of 7wla by Molmil
Mouse Pendrin in bicarbonate and iodide buffer in asymmetric state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLE
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BU of 7wle by Molmil
Mouse Pendrin in chloride and bicarbonate buffer in outward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-13
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WK1
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BU of 7wk1 by Molmil
Mouse Pendrin bound chloride in inward state
分子名称: CHLORIDE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-08
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL7
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BU of 7wl7 by Molmil
Mouse Pendrin in chloride and bicarbonate buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WK7
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BU of 7wk7 by Molmil
Mouse Pendrin bound bicarbonate in inward state
分子名称: BICARBONATE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-08
公開日2023-05-17
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLB
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BU of 7wlb by Molmil
Mouse Pendrin in chloride and iodide buffer in asymmetric state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL8
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BU of 7wl8 by Molmil
Mouse Pendrin in chloride and iodide buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
8IW4
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BU of 8iw4 by Molmil
Cryo-EM structure of the SPE-bound mTAAR9-Gs complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IW9
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BU of 8iw9 by Molmil
Cryo-EM structure of the CAD-bound mTAAR9-Gs complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IW7
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BU of 8iw7 by Molmil
Cryo-EM structure of the PEA-bound mTAAR9-Gs complex
分子名称: 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IWM
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BU of 8iwm by Molmil
Cryo-EM structure of the PEA-bound mTAAR9 complex
分子名称: 2-PHENYLETHYLAMINE, Trace amine-associated receptor 9
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-30
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IWE
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BU of 8iwe by Molmil
Cryo-EM structure of the SPE-mTAAR9 complex
分子名称: SPERMIDINE, Trace amine-associated receptor 9
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
8IW1
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BU of 8iw1 by Molmil
Cryo-EM structure of the PEA-bound mTAAR9-Golf complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(olf) subunit alpha, ...
著者Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K.
登録日2023-03-29
公開日2023-05-31
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
5WXB
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BU of 5wxb by Molmil
crystal structure of ZIKV MTase in complex with SAH
分子名称: MRNA cap 0-1 NS5-type MT, S-ADENOSYL-L-HOMOCYSTEINE
著者Yang, H, Wang, L, Zhou, H.
登録日2017-01-07
公開日2017-05-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.762 Å)
主引用文献The conformational changes of Zika virus methyltransferase upon converting SAM to SAH
Oncotarget, 8, 2017
7CWQ
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BU of 7cwq by Molmil
Crystal structure of a novel cutinase from Burkhoderiales bacterium RIFCSPLOWO2_02_FULL_57_36
分子名称: DLH domain-containing protein, SULFATE ION
著者Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2020-08-30
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis.
Nat Catal, 4, 2021
8DQA
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BU of 8dqa by Molmil
Structure of A. thaliana MIF/D-DT-like protein-3 (MDL3)
分子名称: LS1-like protein
著者Manjula, R, Basquin, J, Lolis, E.
登録日2022-07-18
公開日2023-07-26
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells.
Sci.Signal., 16, 2023

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