5WXB

crystal structure of ZIKV MTase in complex with SAH

Summary for 5WXB

Entry DOI	10.2210/pdb5wxb/pdb
Descriptor	MRNA cap 0-1 NS5-type MT, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywords	zika virus, methyltransferase, sah, transferase
Biological source	Zika virus (strain Mr 766) (ZIKV)
Cellular location	Virion membrane ; Multi-pass membrane protein : A0A167V0D5
Total number of polymer chains	1
Total formula weight	29746.96
Authors	Yang, H.,Wang, L.,Zhou, H. (deposition date: 2017-01-07, release date: 2017-05-17, Last modification date: 2023-11-22)
Primary citation	Zhou, H.,Wang, F.,Wang, H.,Chen, C.,Zhang, T.,Han, X.,Wang, D.,Chen, C.,Wu, C.,Xie, W.,Wang, Z.,Zhang, L.,Wang, L.,Yang, H. The conformational changes of Zika virus methyltransferase upon converting SAM to SAH Oncotarget, 8:14830-14834, 2017 Cited by PubMed: 28122329 DOI: 10.18632/oncotarget.14780 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.762 Å)

Structure validation