8HI2
 
 | |
8HHS
 | |
5YC6
 | | The crystal structure of uPA in complex with 4-Bromobenzylamirne at pH4.6 | | 分子名称: | 1-(4-BROMOPHENYL)METHANAMINE, SULFATE ION, TRIETHYLENE GLYCOL, ... | | 著者 | Jiang, L.G, Zhang, X, Huang, M.D. | | 登録日 | 2017-09-06 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Rsc Adv, 8, 2018
|
|
6GSC
 | | Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | | 著者 | Rashid, G.M.M, Zhang, X, Wilkinson, R.C, Fulop, V, Cottyn, B, Baumberger, S, Bugg, T.D.H. | | 登録日 | 2018-06-13 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Sphingobacterium sp. T2 Manganese Superoxide Dismutase Catalyzes the Oxidative Demethylation of Polymeric Lignin via Generation of Hydroxyl Radical.
ACS Chem. Biol., 13, 2018
|
|
6J7G
 | |
7DB7
 | | Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound GDI05-001 | | 分子名称: | 1-[3-[2-(1H-indol-3-yl)ethylsulfamoyl]phenyl]-3-(1,3-thiazol-2-yl)urea, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ... | | 著者 | Xu, M, Zhang, X, Xu, L, Chen, S. | | 登録日 | 2020-10-19 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis .
J.Biol.Chem., 2021
|
|
8IHP
 | | Structure of Semliki Forest virus VLP in complex with the receptor VLDLR-LA3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ... | | 著者 | Cao, D, Ma, B, Cao, Z, Zhang, X, Xiang, Y. | | 登録日 | 2023-02-23 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of Semliki Forest virus in complex with its receptor VLDLR.
Cell, 186, 2023
|
|
5YC7
 | |
8WOR
 | | Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.
Cell Discov, 10, 2024
|
|
8WOT
 | | Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.
Cell Discov, 10, 2024
|
|
8WOQ
 | | Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.
Cell Discov, 10, 2024
|
|
8WOS
 | | Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.
Cell Discov, 10, 2024
|
|
8HZN
 | |
7DAW
 | | Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase | | 分子名称: | Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, SULFATE ION | | 著者 | Xu, M, Zhang, X, Xu, L, Chen, S. | | 登録日 | 2020-10-18 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis .
J.Biol.Chem., 2021
|
|
7DB8
 | | Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound PF-3845 | | 分子名称: | N-pyridin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methyl]piperidine-1-carboxamide, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ... | | 著者 | Xu, M, Zhang, X, Xu, L, Chen, S. | | 登録日 | 2020-10-19 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis .
J.Biol.Chem., 2021
|
|
4OU1
 | | Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl)(oxiran-2-yl)methanol] | | 分子名称: | (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, BENZOIC ACID, PHOSPHATE ION, ... | | 著者 | Bhabha, G, Zhang, X, Ekiert, D.C. | | 登録日 | 2014-02-14 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4PEK
 | | Crystal structure of a computationally designed retro-aldolase, RA114.3 | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
|
|
4PEJ
 | | Crystal structure of a computationally designed retro-aldolase, RA110.4 (Cys free) | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
|
|
8OPI
 | | VHH Z70 mutant 1 in interaction with PHF6 Tau peptide | | 分子名称: | PHF6 Tau peptide, VHH Z70 mutant 1 | | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | | 登録日 | 2023-04-07 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J.Biol.Chem., 300, 2024
|
|
8OP0
 | | VHH Z70 mutant 20 in interaction with PHF6 Tau peptide | | 分子名称: | Tau PHF6 peptide, VHH Z70 mutant 20 | | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | | 登録日 | 2023-04-06 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J.Biol.Chem., 300, 2024
|
|
5ZGC
 | |
5Z1C
 | | The crystal structure of uPA in complex with 4-Iodobenzylamine at pH7.4 | | 分子名称: | 1-(4-iodophenyl)methanamine, Urokinase-type plasminogen activator | | 著者 | Jiang, L.G, Zhang, X, Luo, Z.P, Huang, M.D. | | 登録日 | 2017-12-25 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Rsc Adv, 49, 2018
|
|
6I52
 | | Yeast RPA bound to ssDNA | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ... | | 著者 | Yates, L.A, Aramayo, R.J, Zhang, X. | | 登録日 | 2018-11-12 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Nat Commun, 9, 2018
|
|
6IFU
 | | Cryo-EM structure of type III-A Csm-CTR2-dsDNA complex | | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
|
|
6IFR
 | | Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
|
|
