4OU1
Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl)(oxiran-2-yl)methanol]
Summary for 4OU1
| Entry DOI | 10.2210/pdb4ou1/pdb |
| Descriptor | Retro-aldolase, design RA114, (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, BENZOIC ACID, ... (5 entities in total) |
| Functional Keywords | tim barrel, retro-aldolase, lyase |
| Biological source | Sulfolobus solfataricus |
| Total number of polymer chains | 1 |
| Total formula weight | 30341.55 |
| Authors | Bhabha, G.,Zhang, X.,Ekiert, D.C. (deposition date: 2014-02-14, release date: 2014-03-05, Last modification date: 2023-09-20) |
| Primary citation | Liu, Y.,Tan, Y.L.,Zhang, X.,Bhabha, G.,Ekiert, D.C.,Genereux, J.C.,Cho, Y.,Kipnis, Y.,Bjelic, S.,Baker, D.,Kelly, J.W. Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts. Proc.Natl.Acad.Sci.USA, 111:4449-4454, 2014 Cited by PubMed: 24591605DOI: 10.1073/pnas.1323268111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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