7XEO
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![BU of 7xeo by Molmil](/molmil-images/mine/7xeo) | MbetaCD treated state of mTRPV2 | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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7XEV
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![BU of 7xev by Molmil](/molmil-images/mine/7xev) | Structure of mTRPV2_2-APB | 分子名称: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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7XEU
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![BU of 7xeu by Molmil](/molmil-images/mine/7xeu) | Structure of mTRPV2_E2 | 分子名称: | CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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7XEW
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![BU of 7xew by Molmil](/molmil-images/mine/7xew) | Structure of mTRPV2_Q525F | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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7XER
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![BU of 7xer by Molmil](/molmil-images/mine/7xer) | Structure of mTRPV2_Q525T | 分子名称: | CHOLESTEROL, Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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7CNN
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![BU of 7cnn by Molmil](/molmil-images/mine/7cnn) | vinorelbine in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
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7CNO
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![BU of 7cno by Molmil](/molmil-images/mine/7cno) | Phomopsin A in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wu, C.Y, Wang, Y.X. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
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7CNM
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![BU of 7cnm by Molmil](/molmil-images/mine/7cnm) | YDX in complex with tubulin | 分子名称: | (2~{S},4~{S})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-4-methyl-3-[[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-cyclohexyl-2-methyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
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1B62
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![BU of 1b62 by Molmil](/molmil-images/mine/1b62) | MUTL COMPLEXED WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (MUTL) | 著者 | Wei, Y. | 登録日 | 1999-01-11 | 公開日 | 1999-04-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell(Cambridge,Mass.), 97, 1999
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4COO
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![BU of 4coo by Molmil](/molmil-images/mine/4coo) | Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | 著者 | McCorvie, T.J, Kopec, J, Vollamar, M, Strain-Damerell, C, Bushell, S, Bradley, A, Tallant, C, Kiyani, W, Froese, D.S, Carpenter, E.S, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | 登録日 | 2014-01-29 | 公開日 | 2014-03-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation. J.Biol.Chem., 289, 2014
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7YEP
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![BU of 7yep by Molmil](/molmil-images/mine/7yep) | 2-APB bound state of mTRPV2 | 分子名称: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2 | 著者 | Su, N. | 登録日 | 2022-07-06 | 公開日 | 2022-08-17 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands. Nat.Chem.Biol., 19, 2023
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3GOX
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![BU of 3gox by Molmil](/molmil-images/mine/3gox) | Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I in the absence of EDTA | 分子名称: | 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', PENTAETHYLENE GLYCOL, ... | 著者 | Sokolowska, M, Czapinska, H, Bochtler, M. | 登録日 | 2009-03-20 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA. Nucleic Acids Res., 37, 2009
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2UZQ
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![BU of 2uzq by Molmil](/molmil-images/mine/2uzq) | |
7BZ7
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![BU of 7bz7 by Molmil](/molmil-images/mine/7bz7) | Template lasso peptide C24 mutant F15Y | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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3ARN
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![BU of 3arn by Molmil](/molmil-images/mine/3arn) | Human dUTPase in complex with novel uracil derivative | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, N-{5-[(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy]-2-methylpentan-2-yl}benzenesulfonamide | 著者 | Chong, K.T, Miyahara, S, Miyakoshi, H, Fukuoka, M. | 登録日 | 2010-12-03 | 公開日 | 2010-12-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors J.Med.Chem., 55, 2012
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7BZ9
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![BU of 7bz9 by Molmil](/molmil-images/mine/7bz9) | Template lasso peptide C24 mutant I4A | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7BZA
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![BU of 7bza by Molmil](/molmil-images/mine/7bza) | Template lasso peptide C24 | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7BZ8
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![BU of 7bz8 by Molmil](/molmil-images/mine/7bz8) | Template lasso peptide C24 mutant V3A | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7VRL
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3ARA
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![BU of 3ara by Molmil](/molmil-images/mine/3ara) | Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors | 分子名称: | 1-[3-({(2R)-2-[hydroxy(diphenyl)methyl]pyrrolidin-1-yl}sulfonyl)propyl]pyrimidine-2,4(1H,3H)-dione, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | 著者 | Chong, K.T, Miyakoshi, H, Miyahara, S, Fukuoka, M. | 登録日 | 2010-11-25 | 公開日 | 2010-12-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors J.Med.Chem., 55, 2012
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3LWV
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![BU of 3lwv by Molmil](/molmil-images/mine/3lwv) | Structure of H/ACA RNP bound to a substrate RNA containing 2'-deoxyuridine | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(du)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | 登録日 | 2010-02-24 | 公開日 | 2010-07-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase . Biochemistry, 49, 2010
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1QFW
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![BU of 1qfw by Molmil](/molmil-images/mine/1qfw) | TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ... | 著者 | Tegoni, M, Spinelli, S, Cambillau, C. | 登録日 | 1999-04-15 | 公開日 | 2000-04-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits. J.Mol.Biol., 289, 1999
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3LWR
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![BU of 3lwr by Molmil](/molmil-images/mine/3lwr) | Structure of H/ACA RNP bound to a substrate RNA containing 4SU | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(4SU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | 登録日 | 2010-02-24 | 公開日 | 2010-07-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase . Biochemistry, 49, 2010
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3LWQ
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![BU of 3lwq by Molmil](/molmil-images/mine/3lwq) | Structure of H/ACA RNP bound to a substrate RNA containing 3MU | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(UR3)P*GP*CP*GP*GP*UP*UP*U)-3, 50S ribosomal protein L7Ae, H/ACA RNA, ... | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | 登録日 | 2010-02-24 | 公開日 | 2010-07-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.678 Å) | 主引用文献 | Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase . Biochemistry, 49, 2010
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7CU6
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![BU of 7cu6 by Molmil](/molmil-images/mine/7cu6) | lasso peptide C24 mutant - A11V2C | 分子名称: | lasso peptide C24_A11V2C | 著者 | Ma, M, Liu, X.H. | 登録日 | 2020-08-21 | 公開日 | 2021-08-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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