6J4P
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6J4V
| Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications | 分子名称: | GLYCEROL, PHOSPHATE ION, Small vasohibin-binding protein, ... | 著者 | Wang, N, Bao, H, Huang, H. | 登録日 | 2019-01-10 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26, 2019
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6I0K
| Structure of quinolinate synthase in complex with 4-mercaptophthalic acid | 分子名称: | 4-mercaptoidenecyclohexa-2,5-diene-1,2-dicarboxylic acid, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C. | 登録日 | 2018-10-26 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem.Commun.(Camb.), 55, 2019
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4ZP1
| Crystal structure of Zymomonas mobilis pyruvate decarboxylase variant Glu473Ala | 分子名称: | GLYCEROL, MAGNESIUM ION, NICKEL (II) ION, ... | 著者 | Wechsler, C, Neumann, P, Tittmann, K. | 登録日 | 2015-05-07 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | 主引用文献 | Tuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot Spot. Chembiochem, 16, 2015
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3IRM
| Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH Cycloguanil | 分子名称: | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, ACETATE ION, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. | 登録日 | 2009-08-24 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase To be Published
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2Q8T
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5DU1
| Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P21 space group. | 分子名称: | Mambalgin-1 | 著者 | Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D. | 登録日 | 2015-09-18 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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2Q8R
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6R1L
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6N2X
| Anti-HIV-1 Fab 2G12 + Man9 re-refinement | 分子名称: | Fab 2G12 heavy chain, Fab 2G12 light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | 登録日 | 2018-11-14 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
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6J4U
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2QCW
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6J4Q
| Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications | 分子名称: | GLYCEROL, N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide, Small vasohibin-binding protein, ... | 著者 | Wang, N, Bao, H, Huang, H. | 登録日 | 2019-01-10 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26, 2019
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6J4O
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6J4S
| Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications | 分子名称: | GLYCEROL, PHOSPHATE ION, Small vasohibin-binding protein, ... | 著者 | Wang, N, Bao, H, Huang, H. | 登録日 | 2019-01-10 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26, 2019
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6N35
| Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement | 分子名称: | BENZOIC ACID, Fab 2G12 heavy chain, Fab 2G12 light chain, ... | 著者 | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | 登録日 | 2018-11-14 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
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3IRO
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5DZ5
| Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P41212 space group | 分子名称: | Mambalgin-1 | 著者 | Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D. | 登録日 | 2015-09-25 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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7L7K
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6N32
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4MIJ
| Crystal structure of a Trap periplasmic solute binding protein from Polaromonas sp. JS666 (Bpro_3107), target EFI-510173, with bound alpha/beta D-Galacturonate, space group P21 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, TRAP dicarboxylate transporter, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Zhao, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-08-31 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4MNI
| Crystal structure of a TRAP periplasmic solute binding protein from Polaromonas sp. JS666 (Bpro_4736), Target EFI-510156, with bound benzoyl formate, space group P6522 | 分子名称: | BENZOYL-FORMIC ACID, TRAP dicarboxylate transporter-DctP subunit | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Zhao, S, Stead, M, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-09-10 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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3INV
| Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH, dUMP AND C-448 ANTIFOLATE | 分子名称: | 1-[3-(2,3-dichlorophenoxy)propoxy]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. | 登録日 | 2009-08-13 | 公開日 | 2010-07-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase To be Published
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3IRN
| Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH AND Cycloguanil | 分子名称: | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. | 登録日 | 2009-08-24 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase To be Published
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1AUR
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