7W3Q
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![BU of 7w3q by Molmil](/molmil-images/mine/7w3q) | Crystal structure of RORgamma in complex with natural inverse agonist | 分子名称: | (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol, Nuclear receptor ROR-gamma, Peptide from Nuclear receptor coactivator 2 | 著者 | Tian, S.Y, Li, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of RORgamma in complex with natural inverse agonist To Be Published
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7W3P
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![BU of 7w3p by Molmil](/molmil-images/mine/7w3p) | Crystal structure of RORgamma in complex with natural inverse agonist | 分子名称: | (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol, Nuclear receptor ROR-gamma, Peptide from Nuclear receptor coactivator 2 | 著者 | Tian, S.Y, Li, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of RORgamma in complex with natural inverse agonist To Be Published
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7XK1
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![BU of 7xk1 by Molmil](/molmil-images/mine/7xk1) | Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase in complex with two tRNAs (both in tRNA binding states) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XK0
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![BU of 7xk0 by Molmil](/molmil-images/mine/7xk0) | Cryo-EM strucrture of Oryza sativa plastid glycyl-tRNA synthetase in complex with tRNA (tRNA locked state) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XV7
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![BU of 7xv7 by Molmil](/molmil-images/mine/7xv7) | |
7XJZ
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![BU of 7xjz by Molmil](/molmil-images/mine/7xjz) | Cryo-EM strucrture of Oryza sativa plastid glycyl-tRNA synthetase in complex with tRNA (tRNA binding state) | 分子名称: | Glycine--tRNA ligase, tRNA(gly) | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7XJY
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![BU of 7xjy by Molmil](/molmil-images/mine/7xjy) | Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase (apo form) | 分子名称: | Glycine--tRNA ligase | 著者 | Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J. | 登録日 | 2022-04-19 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase. Nucleic Acids Res., 51, 2023
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7YX6
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![BU of 7yx6 by Molmil](/molmil-images/mine/7yx6) | Crystal structure of YTHDF2 with compound YLI_DF_027 | 分子名称: | 6-ethyl-1H-pyrimidine-2,4-dione, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-02-15 | 公開日 | 2022-02-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7YXE
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![BU of 7yxe by Molmil](/molmil-images/mine/7yxe) | Crystal structure of YTHDF2 with compound ZA_143 | 分子名称: | GLYCEROL, SODIUM ION, SULFATE ION, ... | 著者 | Nai, F, Zalesak, F, Li, Y, Caflisch, A. | 登録日 | 2022-02-15 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z26
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![BU of 7z26 by Molmil](/molmil-images/mine/7z26) | Crystal structure of YTHDF2 YTH domain in complex with m6A RNA | 分子名称: | GLYCEROL, RNA (5'-R(P*(6MZ)P*CP*U)-3'), SULFATE ION, ... | 著者 | Nai, F, Nachawati, R, Li, Y, Caflisch, A. | 登録日 | 2022-02-25 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z4U
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![BU of 7z4u by Molmil](/molmil-images/mine/7z4u) | Crystal structure of YTHDF2 with compound YLI_DF_028 | 分子名称: | 6-cyclopropyl-3-methyl-1H-pyrimidine-2,4-dione, CHLORIDE ION, GLYCEROL, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-04 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7YWB
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![BU of 7ywb by Molmil](/molmil-images/mine/7ywb) | Crystal structure of YTHDF2 in complex with N6-Methyladenine | 分子名称: | CHLORIDE ION, GLYCEROL, N-METHYL-9H-PURIN-6-AMINE, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-02-12 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z7F
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![BU of 7z7f by Molmil](/molmil-images/mine/7z7f) | Crystal structure of YTHDF2 with compound YLI_DC1_005 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2022-03-15 | 公開日 | 2022-03-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z8W
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![BU of 7z8w by Molmil](/molmil-images/mine/7z8w) | Crystal structure of YTHDF2 with compound YLI_DC1_018 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-18 | 公開日 | 2022-03-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z93
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![BU of 7z93 by Molmil](/molmil-images/mine/7z93) | Crystal structure of YTHDF2 with compound YLI_DF_022 | 分子名称: | 5-azanyl-6-ethyl-1H-pyrimidine-2,4-dione, CHLORIDE ION, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-19 | 公開日 | 2022-03-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z8P
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![BU of 7z8p by Molmil](/molmil-images/mine/7z8p) | Crystal structure of YTHDF2 with compound ZA_166 | 分子名称: | 3-bromanyl-~{N}-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Zalesak, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-18 | 公開日 | 2022-03-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z92
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![BU of 7z92 by Molmil](/molmil-images/mine/7z92) | Crystal structure of YTHDF2 with compound YLI_DF_024 | 分子名称: | 5-azanyl-3,6-dimethyl-1H-pyrimidine-2,4-dione, SULFATE ION, YTH domain-containing family protein 2 | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-19 | 公開日 | 2022-03-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z8X
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![BU of 7z8x by Molmil](/molmil-images/mine/7z8x) | Crystal structure of YTHDF2 with compound YLI_DC1_017 | 分子名称: | 6-methoxy-1H-pyrimidine-2,4-dione, SULFATE ION, YTH domain-containing family protein 2 | 著者 | Nachawati, R, Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-18 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7ZG4
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![BU of 7zg4 by Molmil](/molmil-images/mine/7zg4) | Crystal structure of YTHDF2 with compound YLI_DF_042 | 分子名称: | GLYCEROL, N-methylpyrimidine-2-carboximidamide, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-04-01 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z7B
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![BU of 7z7b by Molmil](/molmil-images/mine/7z7b) | Crystal structure of YTHDF2 with compound YLI_DC1_003 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2022-03-15 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z5M
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![BU of 7z5m by Molmil](/molmil-images/mine/7z5m) | Crystal structure of YTHDF2 with compound YLI_DC1_008 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Nai, F, Li, Y, Caflisch, A. | 登録日 | 2022-03-09 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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7Z54
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![BU of 7z54 by Molmil](/molmil-images/mine/7z54) | Crystal structure of YTHDF2 with compound YLI_DC1_006 | 分子名称: | 9-cyclopropyl-~{N}-methyl-purin-6-amine, CHLORIDE ION, GLYCEROL, ... | 著者 | Nai, F, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2022-03-07 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13, 2022
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6RT5
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![BU of 6rt5 by Molmil](/molmil-images/mine/6rt5) | |
6RT4
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![BU of 6rt4 by Molmil](/molmil-images/mine/6rt4) | |
8I91
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![BU of 8i91 by Molmil](/molmil-images/mine/8i91) | ACE2-SIT1 complex bound with proline | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | 登録日 | 2023-02-06 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1. Cell Discov, 9, 2023
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