7Z5M

Crystal structure of YTHDF2 with compound YLI_DC1_008

Summary for 7Z5M

Entry DOI	10.2210/pdb7z5m/pdb
Descriptor	YTH domain-containing family protein 2, SULFATE ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	epitranscriptomic reader, m6a reader, rna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	40101.26
Authors	Nai, F.,Li, Y.,Caflisch, A. (deposition date: 2022-03-09, release date: 2022-06-22, Last modification date: 2024-01-31)
Primary citation	Nai, F.,Nachawati, R.,Zalesak, F.,Wang, X.,Li, Y.,Caflisch, A. Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13:1500-1509, 2022 Cited by PubMed: 36110386 DOI: 10.1021/acsmedchemlett.2c00303 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation