8X3S
| Crystal structure of human WDR5 in complex with PTEN | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, WD repeat-containing protein 5 | 著者 | Liu, Y, Huang, X, Shang, X. | 登録日 | 2023-11-14 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif. Cell Death Dis, 15, 2024
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8XYU
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8XYS
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8XYW
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8XYT
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8XYR
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8XYV
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8Y6U
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8HAF
| PTHrP-PTH1R-Gs complex | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | 登録日 | 2022-10-26 | 公開日 | 2022-12-21 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1. Acta Pharmacol.Sin., 44, 2023
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8HA0
| Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1 | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | 登録日 | 2022-10-26 | 公開日 | 2022-12-21 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1. Acta Pharmacol.Sin., 44, 2023
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8HAO
| Human parathyroid hormone receptor-1 dimer | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha, ... | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | 登録日 | 2022-10-26 | 公開日 | 2022-12-21 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1. Acta Pharmacol.Sin., 44, 2023
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8I6K
| Structure of hMNDA HIN with dsDNA | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ... | 著者 | Li, Y.L, Jin, T.C. | 登録日 | 2023-01-28 | 公開日 | 2023-07-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein. Int.J.Biol.Macromol., 245, 2023
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8H4U
| Cryo-EM structure of a riboendonuclease | 分子名称: | CRISPR-associated endonuclease Cas9 | 著者 | Li, Z, Wang, F. | 登録日 | 2022-10-11 | 公開日 | 2023-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola. J.Mol.Biol., 435, 2023
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8H41
| Crystal structure of a decarboxylase from Trichosporon moniliiforme in complex with o-nitrophenol | 分子名称: | MAGNESIUM ION, O-NITROPHENOL, Salicylate decarboxylase | 著者 | Gao, J, Zhao, Y.P, Li, Q, Liu, W.D, Sheng, X. | 登録日 | 2022-10-09 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | A Combined Computational-Experimental Study on the Substrate Binding and Reaction Mechanism of Salicylic Acid Decarboxylase Catalysts, 12, 2022
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7YP3
| Crystal structure of elaiophylin glycosyltransferase in complex with elaiophylin | 分子名称: | ACETATE ION, Elaiophylin, GLYCEROL, ... | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP6
| Crystal structure of elaiophylin glycosyltransferase in complex with UDP | 分子名称: | Glycosyltransferase, R-1,2-PROPANEDIOL, URIDINE-5'-DIPHOSPHATE | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP5
| Crystal structure of elaiophylin glycosyltransferase in complex with TDP | 分子名称: | CHLORIDE ION, Glycosyltransferase, R-1,2-PROPANEDIOL, ... | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP4
| Crystal structure of elaiophylin glycosyltransferase in apo-form | 分子名称: | Glycosyltransferase, R-1,2-PROPANEDIOL | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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6JPE
| Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1 | 分子名称: | Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION | 著者 | Chen, X, Dai, S, Zhou, Z, Chen, Y. | 登録日 | 2019-03-26 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma. J.Med.Chem., 63, 2020
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7DNU
| mRNA-decapping enzyme g5Rp with inhibitor insp6 complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, mRNA-decapping protein g5R | 著者 | Yang, Y, Chen, C, Li, L, Li, X.H, Su, D. | 登録日 | 2020-12-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Structural Insight into Molecular Inhibitory Mechanism of InsP 6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. J.Virol., 96, 2022
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7DNT
| mRNA-decapping enzyme g5Rp | 分子名称: | mRNA-decapping protein g5R | 著者 | Yang, Y, Chen, C, Li, L, Li, X.H, Su, D. | 登録日 | 2020-12-10 | 公開日 | 2022-03-09 | 最終更新日 | 2022-12-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Insight into Molecular Inhibitory Mechanism of InsP 6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. J.Virol., 96, 2022
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7EPT
| Structural basis for the tethered peptide activation of adhesion GPCRs | 分子名称: | Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Ping, Y.-Q, Xiao, P, Yang, F, Zhao, R.-J, Guo, S.-C, Yan, X, Wu, X, Liebscher, I, Xu, H.E, Sun, J.-P. | 登録日 | 2021-04-27 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for the tethered peptide activation of adhesion GPCRs. Nature, 604, 2022
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7EQ1
| GPR114-Gs-scFv16 complex | 分子名称: | Adhesion G-protein coupled receptor G5, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ping, Y. | 登録日 | 2021-04-28 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for the tethered peptide activation of adhesion GPCRs. Nature, 604, 2022
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7BYI
| Structure of SHMT2 in complex with CBX | 分子名称: | CARBENOXOLONE, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Li, L, Chen, Y, Lu, D, Zhang, C, Su, D. | 登録日 | 2020-04-23 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structure of SHMT2 with CBX To Be Published
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7C43
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