5I4C
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![BU of 5i4c by Molmil](/molmil-images/mine/5i4c) | Crystal structure of non-phosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli | 分子名称: | Transcriptional regulatory protein RcsB | 著者 | Filippova, E.V, Wawrzak, Z, Minasov, G, Ruan, J, Pshenychnyi, S, Wolfe, A.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-11 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of nonphosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli. Protein Sci., 25, 2016
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5I0G
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![BU of 5i0g by Molmil](/molmil-images/mine/5i0g) | Cycloalternan-degrading enzyme from Trueperella pyogenes in complex with cycloalternan | 分子名称: | Cyclic alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose, Glycoside hydrolase family 31, SUCCINIC ACID | 著者 | Light, S.H, Minasov, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-02-03 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure, 25, 2017
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4X0O
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![BU of 4x0o by Molmil](/molmil-images/mine/4x0o) | Beta-ketoacyl-(acyl carrier protein) synthase III-2 (FabH2) from Vibrio cholerae soaked with Acetyl-CoA | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, COENZYME A, MALONATE ION, ... | 著者 | Hou, J, Chruszcz, M, Zheng, H, Cooper, D.R, Chordia, M.D, Zimmerman, M.D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-11-21 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and enzymatic studies of beta-ketoacyl-(acyl carrier protein) synthase III (FabH) from Vibrio cholerae to be published
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4YGO
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![BU of 4ygo by Molmil](/molmil-images/mine/4ygo) | Dodecameric structure of spermidine N-acetyltransferase from Vibrio cholerae in intermediate state | 分子名称: | CALCIUM ION, METHANOL, Spermidine n1-acetyltransferase | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-02-26 | 公開日 | 2015-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG. J.Mol.Biol., 427, 2015
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4WK6
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![BU of 4wk6 by Molmil](/molmil-images/mine/4wk6) | Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) (G141A) from Vibrio cholerae in complex with NADPH | 分子名称: | 3-oxoacyl-[acyl-carrier protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL | 著者 | Hou, J, Zheng, H, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-10-01 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol., 198, 2015
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4WH5
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![BU of 4wh5 by Molmil](/molmil-images/mine/4wh5) | Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, lincomycin-bound | 分子名称: | CHLORIDE ION, LINCOMYCIN, Lincosamide resistance protein, ... | 著者 | Stogios, P.J, Dong, A, Minasov, G, Evdokimova, E, Egorova, O, Kudritska, M, Yim, O, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-09-20 | 公開日 | 2014-11-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | CRYSTAL STRUCTURE OF LINCOSAMIDE ANTIBIOTIC ADENYLYLTRANSFERASE LNUA, LINCOMYCIN BOUND To Be Published
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7RCA
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![BU of 7rca by Molmil](/molmil-images/mine/7rca) | Crystal structure of Aro2p chorismate synthase from Candida lusitaniae | 分子名称: | CHLORIDE ION, Chorismate synthase, SULFATE ION | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-07 | 公開日 | 2021-07-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structure of Aro2p chorismate synthase from Candida lusitaniae To Be Published
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7RGN
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![BU of 7rgn by Molmil](/molmil-images/mine/7rgn) | Crystal structure of putative fructose-1,6-bisphosphate aldolase from Candida auris | 分子名称: | Fructose-bisphosphate aldolase, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-15 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of putative fructose-1,6-bisphosphate aldolase from Candida auris To Be Published
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7REU
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![BU of 7reu by Molmil](/molmil-images/mine/7reu) | Crystal structure of Aro4p, 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase from Candida auris, L-Tyr complex | 分子名称: | 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, CHLORIDE ION, GLYCEROL, ... | 著者 | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-13 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Crystal structure of Aro4p, 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase from Candida auris, L-Tyr complex To Be Published
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7RGE
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![BU of 7rge by Molmil](/molmil-images/mine/7rge) | Crystal structure of phosphoadenylyl-sulfate (PAPS) reductase from Candida auris, phosphate complex | 分子名称: | 3'-phosphoadenylylsulfate reductase, GLYCEROL, PHOSPHATE ION | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-15 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal structure of phosphoadenylyl-sulfate (PAPS) reductase from Candida auris, phosphate complex To Be Published
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7RQG
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![BU of 7rqg by Molmil](/molmil-images/mine/7rqg) | Crystal structure of the Nsp3 Y3 domain from SARS-CoV-2 | 分子名称: | Non-structural protein 3 | 著者 | Stogios, P.J, Skarina, T, Chang, C, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-06 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal structure of the Nsp3 Y3 domain from SARS-CoV-2 To Be Published
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7RC0
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![BU of 7rc0 by Molmil](/molmil-images/mine/7rc0) | X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-091-20 | 分子名称: | 3C-like proteinase, 5-chloro-4-methylpyridin-3-yl 1H-indole-4-carboxylate, SODIUM ION | 著者 | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-06 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
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7RBS
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![BU of 7rbs by Molmil](/molmil-images/mine/7rbs) | The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with human ISG15 | 分子名称: | Papain-like protease, Ubiquitin-like protein ISG15, ZINC ION | 著者 | Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-06 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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7RC1
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![BU of 7rc1 by Molmil](/molmil-images/mine/7rc1) | X-ray Structure of SARS-CoV main protease covalently modified by compound GRL-0686 | 分子名称: | 3C-like proteinase, 5-chloropyridin-3-yl 1-(3-nitrobenzene-1-sulfonyl)-1H-indole-5-carboxylate, DIMETHYL SULFOXIDE | 著者 | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-07 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
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7RBZ
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![BU of 7rbz by Molmil](/molmil-images/mine/7rbz) | X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-017-20 | 分子名称: | 3C-like proteinase, 5-chloropyridin-3-yl 2,3-dihydro-1H-indole-4-carboxylate | 著者 | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-06 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
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7RBR
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![BU of 7rbr by Molmil](/molmil-images/mine/7rbr) | The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with a Lys48-linked di-ubiquitin | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Papain-like protease, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-06 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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7ROA
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![BU of 7roa by Molmil](/molmil-images/mine/7roa) | Crystal structure of EntV136 from Enterococcus faecalis | 分子名称: | EntV | 著者 | Stogios, P.J, Evdokimova, E, Kim, Y, Garsin, D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2021-07-30 | 公開日 | 2022-10-12 | 最終更新日 | 2023-01-25 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections. Nat Commun, 13, 2022
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6O62
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![BU of 6o62 by Molmil](/molmil-images/mine/6o62) | Crystal structure of Sec4p, a Rab family GTPase from Candida albicans | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein SEC4 | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-03-05 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | To be published To Be Published
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6OX6
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![BU of 6ox6 by Molmil](/molmil-images/mine/6ox6) | Crystal structure of the complex between the Type VI effector Tas1 and its immunity protein | 分子名称: | ACETATE ION, PA14_01140, Tas1 | 著者 | Ahmad, S, Stogios, P.J, Skarina, T, Whitney, J, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-13 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp. Nature, 575, 2019
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6OZV
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![BU of 6ozv by Molmil](/molmil-images/mine/6ozv) | The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | 著者 | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-16 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6P1J
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![BU of 6p1j by Molmil](/molmil-images/mine/6p1j) | The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module | 分子名称: | ACETATE ION, CHLORIDE ION, CITRATE ANION, ... | 著者 | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-20 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6P7U
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![BU of 6p7u by Molmil](/molmil-images/mine/6p7u) | |
6PI9
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![BU of 6pi9 by Molmil](/molmil-images/mine/6pi9) | Crystal structure of 16S rRNA methyltransferase RmtF in complex with S-Adenosyl-L-homocysteine | 分子名称: | 16S rRNA (guanine(1405)-N(7))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Stogios, P.J, Kim, Y, Evdokimova, E, Di Leo, R, Semper, C, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-06-26 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of 16S rRNA methylase RmtF in complex with S-Adenosyl-L-homocysteine To be Published
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6P3I
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![BU of 6p3i by Molmil](/molmil-images/mine/6p3i) | The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with Mg | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ... | 著者 | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-23 | 公開日 | 2019-06-05 | 最終更新日 | 2020-03-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6PLK
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![BU of 6plk by Molmil](/molmil-images/mine/6plk) | |