5FO4
 
 | | Crystal structure of the P.falciparum cytosolic leucyl-tRNA synthetase editing domain (space group P1) | | 分子名称: | LEUCYL TRNA SYNTHASE | | 著者 | Palencia, A, Sonoiki, E, Guo, D, Ahyong, V, Dong, C, Li, X, Hernandez, V.S, Gut, J, Legac, J, Cooper, R, Alley, M.R.K, Freund, Y.R, DeRisi, J, Cusack, S, Rosenthal, P.J. | | 登録日 | 2015-11-18 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Anti-Malarial Benzoxaboroles Target P. Falciparum Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
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3OBH
 | | X-ray crystal structure of protein SP_0782 (7-79) from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR104 | | 分子名称: | ACETIC ACID, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kuzin, A, Abashidze, M, Lew, S, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-08-06 | | 公開日 | 2010-09-15 | | 最終更新日 | 2012-02-22 | | 実験手法 | X-RAY DIFFRACTION (1.891 Å) | | 主引用文献 | X-ray crystal structure of protein SP_0782 (7-79) from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR104
To be Published
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5FLH
 | | Free state of Ni-quercetinase | | 分子名称: | DIMETHYL SULFOXIDE, NICKEL (II) ION, NITRATE ION, ... | | 著者 | Jeoung, J.-H, Nianios, D, Fetzner, S, Dobbek, H. | | 登録日 | 2015-10-26 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Quercetin 2,4-Dioxygenase Activates Dioxygen in a Side-on O2 -Ni Complex.
Angew.Chem.Int.Ed.Engl., 55, 2016
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5FP0
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, N-cyclopentyl-2-[4-(trifluoromethyl)phenyl]-3H-benzimidazole-4-sulfonamide | | 著者 | Xue, Y, Olsson, T, Johansson, C.A, Oster, L, Beisel, H.G, Rohman, M, Karis, D, Backstrom, S. | | 登録日 | 2015-11-26 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration.
Chemmedchem, 11, 2016
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7NQA
 | | Crystal structure of Nucleoporin-98 nanobody MS98-6 complex solved at 2.2A resolution | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Nup98 Nanobody MS98-6, Nuclear pore complex protein Nup98-Nup96, ... | | 著者 | Sola-Colom, M, Trakhanov, S, Goerlich, D. | | 登録日 | 2021-03-01 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 2024
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5G4K
 | | Phloroglucinol reductase from Clostridium sp. apo-form | | 分子名称: | OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY PROTEIN | | 著者 | Conradt, D, Hermann, B, Gerhardt, S, Einsle, O, Mueller, M. | | 登録日 | 2016-05-13 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Biocatalytic Properties and Structural Analysis of Phloroglucinol Reductases.
Angew.Chem.Int.Ed.Engl., 55, 2016
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3O8Z
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5GAG
 | | RNC in complex with SRP-SR in the closed state | | 分子名称: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | | 著者 | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | 登録日 | 2015-11-26 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
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3SFV
 | | Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ... | | 著者 | Yin, K, Lu, D, Zhu, D, Zhang, H, Li, B, Xu, S, Gu, L. | | 登録日 | 2011-06-14 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
Plos Pathog., 8, 2012
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3O0A
 | | Crystal structure of the wild type CP1 hydrolitic domain from Aquifex Aeolicus leucyl-trna | | 分子名称: | Leucyl-tRNA synthetase subunit alpha | | 著者 | Cura, V, Olieric, N, Wang, E.-D, Moras, D, Eriani, G, Cavarelli, J. | | 登録日 | 2010-07-19 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal Structure of the Wild Type and Two Mutants of the Cp1 Hydrolytic Domain from Aquifex Aeolicus Leucyl-tRNA Synthetase
To be Published
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5GP7
 | | Structural basis for the binding between Tankyrase-1 and USP25 | | 分子名称: | GLYCEROL, Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25 | | 著者 | Liu, J, Xu, D, Fu, T, Pan, L. | | 登録日 | 2016-08-01 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
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2HZ7
 | | Crystal structure of the Glutaminyl-tRNA synthetase from Deinococcus radiodurans | | 分子名称: | Glutaminyl-tRNA synthetase | | 著者 | Deniziak, M, Sauter, C, Becker, H.D, Paulus, C, Giege, R, Kern, D. | | 登録日 | 2006-08-08 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation
Nucleic Acids Res., 35, 2007
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5FQU
 | | Orthorhombic crystal structure of of PlpD (selenomethionine derivative) | | 分子名称: | AZIDE ION, PATATIN-LIKE PROTEIN, PLPD, ... | | 著者 | Vinicius da Mata Madeira, P, Zouhir, S, Basso, P, Neves, D, Laubier, A, Salacha, R, Bleves, S, Faudry, E, Contreras-Martel, C, Dessen, A. | | 登録日 | 2015-12-14 | | 公開日 | 2016-04-06 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas Aeruginosa.
J.Mol.Biol., 428, 2016
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5FVM
 | | Cryo electron microscopy of a complex of Tor and Lst8 | | 分子名称: | SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 | | 著者 | Baretic, D, Berndt, A, Ohashi, Y, Johnson, C.M, Williams, R.L. | | 登録日 | 2016-02-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Tor Forms a Dimer Through an N-Terminal Helical Solenoid with a Complex Topology
Nat.Commun., 7, 2016
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5FWB
 | | Human Spectrin SH3 domain D48G, E7F, K60F | | 分子名称: | SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 | | 著者 | Gallego, P, Navarro, S, Ventura, S, Reverter, D. | | 登録日 | 2016-02-12 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
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5F81
 | | Acoustic injectors for drop-on-demand serial femtosecond crystallography | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Roessler, C.G, Agarwal, R, Allaire, M, Alonso-Mori, R, Andi, B, Bachega, J.F.R, Bommer, M, Brewster, A.S, Browne, M.C, Chatterjee, R, Cho, E, Cohen, A.E, Cowan, M, Datwani, S, Davidson, V.L, Defever, J, Eaton, B, Ellson, R, Feng, Y, Ghislain, L.P, Glownia, J.M, Han, G, Hattne, J, Hellmich, J, Heroux, A, Ibrahim, M, Kern, J, Kuczewski, A, Lemke, H.T, Liu, P, Majlof, L, McClintock, W.M, Myers, S, Nelsen, S, Olechno, J, Orville, A.M, Sauter, N.K, Soares, A.S, Soltis, M.S, Song, H, Stearns, R.G, Tran, R, Tsai, Y, Uervirojnangkoorn, M, Wilmot, C.M, Yachandra, V, Yano, J, Yukl, E.T, Zhu, D, Zouni, A. | | 登録日 | 2015-12-08 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.
Structure, 24, 2016
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5FLJ
 | | enzyme-substrate-dioxygen complex of Ni-quercetinase | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, NICKEL (II) ION, ... | | 著者 | Jeoung, J.-H, Nianios, D, Fetzner, S, Dobbek, H. | | 登録日 | 2015-10-26 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.818 Å) | | 主引用文献 | Quercetin 2,4-Dioxygenase Activates Dioxygen in a Side-on O2 -Ni Complex.
Angew.Chem.Int.Ed.Engl., 55, 2016
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5G05
 | | Cryo-EM structure of combined apo phosphorylated APC | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | 著者 | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | 登録日 | 2016-03-16 | | 公開日 | 2016-05-25 | | 最終更新日 | 2019-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
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5FW4
 | | Structure of Thermobifida fusca DyP-type Peroxidase and Activity towards Kraft Lignin and Lignin Model Compounds | | 分子名称: | DYE-DECOLORIZING PEROXIDASE TFU_3078, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Rahmanpour, R, Rea, D, Jamshidi, S, Fulop, V, Bugg, T.D.H. | | 登録日 | 2016-02-11 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Thermobifida Fusca Dyp-Type Peroxidase and Activity Towards Kraft Lignin and Lignin Model Compounds.
Arch.Biochem.Biophys., 594, 2016
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1C9Y
 | | HUMAN ORNITHINE TRANSCARBAMYLASE: CRYSTALLOGRAPHIC INSIGHTS INTO SUBSTRATE RECOGNITION AND CATALYTIC MECHANISM | | 分子名称: | NORVALINE, ORNITHINE CARBAMOYLTRANSFERASE, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER | | 著者 | Shi, D, Yu, X, Morizono, H, Tuchman, M, Allewell, N.M. | | 登録日 | 1999-08-03 | | 公開日 | 2000-06-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution.
Proteins, 39, 2000
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5FLE
 | | High resolution NI,FE-CODH-320 mV with CN state | | 分子名称: | CARBON MONOXIDE DEHYDROGENASE 2, FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Ciaccafava, A, Tombolelli, D, Domnik, L, Fesseler, J, Jeoung, J.-H, Dobbek, H, Mroginski, M.A, Hildebrandt, P, Zebger, I. | | 登録日 | 2015-10-26 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | When the inhibitor tells more than the substrate: the cyanide-bound state of a carbon monoxide dehydrogenase.
Chem Sci, 7, 2016
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5FBL
 | | PI4KB in complex with Rab11 and the MI356 Inhibitor | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.372 Å) | | 主引用文献 | PI4KB in complex with Rab11 and the MI356 Inhibitor
To Be Published
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5FBV
 | | PI4KB in complex with Rab11 and the MI364 Inhibitor | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.285 Å) | | 主引用文献 | PI4KB in complex with Rab11 and the MI364 Inhibitor
To Be Published
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5FNU
 | | Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor. | | 分子名称: | (3S)-3-(7-methoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((R)-4-methyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)phenyl)propanoic acid, CHLORIDE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | | 著者 | Davies, T.G, Wixted, W.E, Coyle, J.E, Griffiths-Jones, C, Hearn, K, McMenamin, R, Norton, D, Rich, S.J, Richardson, C, Saxty, G, Willems, H.M.G, Woolford, A.J, Cottom, J.E, Kou, J, Yonchuk, J.G, Feldser, H.G, Sanchez, Y, Foley, J.P, Bolognese, B.J, Logan, G, Podolin, P.L, Yan, H, Callahan, J.F, Heightman, T.D, Kerns, J.K. | | 登録日 | 2015-11-16 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Mono-Acidic Inhibitors of the Kelch-Like Ech-Associated Protein 1 : Nuclear Factor Erythroid 2-Related Factor 2 (Keap1:Nrf2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
J.Med.Chem., 59, 2016
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1CDQ
 | | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | | 分子名称: | CD59 | | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | | 登録日 | 1994-06-01 | | 公開日 | 1994-09-30 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
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