5FP0

ligand complex structure of soluble epoxide hydrolase

Summary for 5FP0

Entry DOI	10.2210/pdb5fp0/pdb
Descriptor	BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, N-cyclopentyl-2-[4-(trifluoromethyl)phenyl]-3H-benzimidazole-4-sulfonamide, ... (4 entities in total)
Functional Keywords	hydrolase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P34913
Total number of polymer chains	1
Total formula weight	62490.27
Authors	Xue, Y.,Olsson, T.,Johansson, C.A.,Oster, L.,Beisel, H.G.,Rohman, M.,Karis, D.,Backstrom, S. (deposition date: 2015-11-26, release date: 2016-03-02, Last modification date: 2016-03-16)
Primary citation	Xue, Y.,Olsson, T.,Johansson, C.A.,Oster, L.,Beisel, H.,Rohman, M.,Karis, D.,Backstrom, S. Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration. Chemmedchem, 11:497-, 2016 Cited by PubMed: 26845235 DOI: 10.1002/CMDC.201500575 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation