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7CI1
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BU of 7ci1 by Molmil
Crystal structure of AcrVA2
分子名称: 1,2-ETHANEDIOL, AcrVA2, SPERMIDINE
著者Chen, P, Cheng, Z, Wang, Y.
登録日2020-07-07
公開日2020-10-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Study on Anti-CRISPR Protein AcrVA2
Prog.Biochem.Biophys., 2021
7CI2
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BU of 7ci2 by Molmil
Crystal structure of AcrVA2 in complex with partial MbCpf1
分子名称: AcrVA2, MbCpf1
著者Chen, P, Cheng, Z, Wang, Y.
登録日2020-07-07
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Study on Anti-CRISPR Protein AcrVA2
Prog.Biochem.Biophys., 2021
7DO4
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BU of 7do4 by Molmil
Crystal structure of CD97-CD55 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Niu, M, Song, G.
登録日2020-12-11
公開日2021-09-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs.
J.Biol.Chem., 296, 2021
7BVP
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BU of 7bvp by Molmil
AdhE spirosome in extended conformation
分子名称: Aldehyde-alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Kim, G.J, Song, J.J.
登録日2020-04-11
公開日2020-06-24
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Aldehyde-alcohol dehydrogenase undergoes structural transition to form extended spirosomes for substrate channeling.
Commun Biol, 3, 2020
7DCL
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BU of 7dcl by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96I/A38S AB5
分子名称: CHLORIDE ION, HEME C, ZINC ION, ...
著者Song, W.J, Yu, J.
登録日2020-10-26
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
6BAN
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BU of 6ban by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain R11 Heavy chain, Variable domain of R11 Light Chain
著者Park, H, Rader, C.
登録日2017-10-14
公開日2018-06-13
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7DEK
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BU of 7dek by Molmil
Pseudomonas aeruginosa FK506-binding protein PaFkbA
分子名称: Peptidyl-prolyl cis-trans isomerase
著者Ynag, J, Huang, Q, Bao, R.
登録日2020-11-04
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural characterization of PaFkbA: A periplasmic chaperone from Pseudomonas aeruginosa .
Comput Struct Biotechnol J, 19, 2021
5XBL
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BU of 5xbl by Molmil
Structure of nuclease in complex with associated protein
分子名称: Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER)
著者Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z.
登録日2017-03-20
公開日2017-06-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.052 Å)
主引用文献Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature, 546, 2017
8I4S
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BU of 8i4s by Molmil
the complex structure of SARS-CoV-2 Mpro with D8
分子名称: 3-(4-fluoranyl-3-methyl-phenyl)-2-(2-methylpropyl)-5,6,7-tris(oxidanyl)quinazolin-4-one, ORF1a polyprotein
著者Lu, M.
登録日2023-01-21
公開日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of quinazolin-4-one-based non-covalent inhibitors targeting the severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2 M pro ).
Eur.J.Med.Chem., 257, 2023
8IOO
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BU of 8ioo by Molmil
Crystal structure of Deinococcus radiodurans RecJ-like protein in complex with Mg2+
分子名称: MAGNESIUM ION, RecJ-like protein, SULFATE ION
著者Cheng, K.
登録日2023-03-13
公開日2024-03-20
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional investigation of the DHH/DHHA1 family proteins in Deinococcus radiodurans.
Nucleic Acids Res., 52, 2024
7YGV
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BU of 7ygv by Molmil
Crystal structure of the Ca2+-bound EFhd1/Swiprosin-2
分子名称: CALCIUM ION, EF-hand domain-containing protein D1, GLYCEROL, ...
著者Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Ynag, J, Eom, S.H.
登録日2022-07-12
公開日2023-03-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2.
Iucrj, 10, 2023
8K14
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BU of 8k14 by Molmil
X-ray crystal structure of 18a in BRD4(1)
分子名称: 4-[8-methoxy-2-methyl-1-(1-phenylethyl)imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole, Bromodomain-containing protein 4
著者Xu, H, Shen, H, Zhang, Y, Xu, Y, Li, R.
登録日2023-07-10
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.
Eur.J.Med.Chem., 263, 2024
8K31
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BU of 8k31 by Molmil
The complex of WRKY33 C terminal DBD and SIB1
分子名称: Probable WRKY transcription factor 33, Sigma factor binding protein 1, chloroplastic, ...
著者Dong, X, Gong, Z, Hu, Y.F.
登録日2023-07-14
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis for the regulation of plant transcription factor WRKY33 by the VQ protein SIB1.
Commun Biol, 7, 2024
8JAT
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BU of 8jat by Molmil
Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans
分子名称: 3-ketodihydrosphingosine reductase TSC10, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, P, Kuang, Z.
登録日2023-05-07
公開日2023-06-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans.
Biochem.Biophys.Res.Commun., 670, 2023
6JB6
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BU of 6jb6 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
To Be Published
6JB7
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BU of 6jb7 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution
To Be Published
7CSW
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BU of 7csw by Molmil
Pseudomonas aeruginosa antitoxin HigA with pa2440 promoter
分子名称: HTH cro/C1-type domain-containing protein, pa2440
著者Song, Y.J, Luo, G.H, Bao, R.
登録日2020-08-17
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs.
Environ.Microbiol., 23, 2021
7CM5
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BU of 7cm5 by Molmil
Full-length Sarm1 in a self-inhibited state
分子名称: NAD(+) hydrolase SARM1
著者Zhang, Z, Jiang, Y.
登録日2020-07-24
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Nature, 588, 2020
7CSV
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BU of 7csv by Molmil
Pseudomonas aeruginosa antitoxin HigA
分子名称: HTH cro/C1-type domain-containing protein
著者Song, Y.J, Luo, G.H, Bao, R.
登録日2020-08-17
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs.
Environ.Microbiol., 23, 2021
7CM7
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BU of 7cm7 by Molmil
NAD+-bound Sarm1 E642A in the self-inhibited state
分子名称: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, Z, Jiang, Y.
登録日2020-07-25
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Nature, 588, 2020
7CSY
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BU of 7csy by Molmil
Pseudomonas aeruginosa antitoxin HigA with higBA promoter
分子名称: DNA (28-MER), DNA (29-MER), HTH cro/C1-type domain-containing protein, ...
著者Song, Y.J, Luo, G.H, Bao, R.
登録日2020-08-17
公開日2021-01-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs.
Environ.Microbiol., 23, 2021
7CM6
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BU of 7cm6 by Molmil
NAD+-bound Sarm1 in the self-inhibited state
分子名称: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, Z, Jiang, Y.
登録日2020-07-25
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Nature, 588, 2020
7Y56
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BU of 7y56 by Molmil
Crystal structure of NS1 nuclease domain in P41212 space group
分子名称: GLYCEROL, NS1 protein
著者Zhang, X.Y, Gan, J.H.
登録日2022-06-16
公開日2023-07-05
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7Y57
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BU of 7y57 by Molmil
Crystal structure of NS1 nuclease domain in P21 space group
分子名称: NS1 protein, PHOSPHATE ION
著者Zhang, X.Y, Gan, J.H.
登録日2022-06-16
公開日2023-07-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.183 Å)
主引用文献Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7CL8
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BU of 7cl8 by Molmil
Testosterone-bound structure of CYP154C2 from Streptomyces avermitilis in an closed conformation
分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Xu, L.H, Fushinobu, S.
登録日2020-07-20
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Improved 2 alpha-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design.
Appl.Environ.Microbiol., 89, 2023

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