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8XOO
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BU of 8xoo by Molmil
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease proteolytic subunit, ...
著者Xu, X, Long, F.
登録日2024-01-01
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (1.84 Å)
主引用文献Structural insights into the Clp protein degradation machinery.
Mbio, 15, 2024
8XN4
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BU of 8xn4 by Molmil
Cryo-EM structure of the ClpP degradation system in Streptomyces hawaiiensis
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Xu, X, Long, F.
登録日2023-12-29
公開日2024-03-27
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Structural insights into the Clp protein degradation machinery.
Mbio, 15, 2024
8Y5W
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BU of 8y5w by Molmil
human NaS1 intermediate state 2
分子名称: SODIUM ION, SULFATE ION, Solute carrier family 13 member 1
著者Zhang, S.S.
登録日2024-02-01
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
8Y5Z
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BU of 8y5z by Molmil
human NaS1 inward state
分子名称: SODIUM ION, SULFATE ION, Solute carrier family 13 member 1
著者Zhang, S.S.
登録日2024-02-01
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
8Y5Y
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BU of 8y5y by Molmil
human NaS1 outward state
分子名称: SULFATE ION, Solute carrier family 13 member 1
著者Zhang, S.S.
登録日2024-02-01
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
8Y5X
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BU of 8y5x by Molmil
human NaS1 intermediate state 3
分子名称: SODIUM ION, SULFATE ION, Solute carrier family 13 member 1
著者Zhang, S.S.
登録日2024-02-01
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for the reaction cycle and transport mechanism of human Na + -sulfate cotransporter NaS1 (SLC13A1).
Sci Adv, 10, 2024
7XYD
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BU of 7xyd by Molmil
Crystal structure of TMPRSS2 in complex with Nafamostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0F
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BU of 7y0f by Molmil
Crystal structure of TMPRSS2 in complex with UK-371804
分子名称: 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0E
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Crystal structure of TMPRSS2 in complex with Camostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8Z7M
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BU of 8z7m by Molmil
The crystal structure of AFM-1
分子名称: Metallo-beta-lactamase type 2, ZINC ION
著者Xiao, Y.J, Wang, Z.F.
登録日2024-04-20
公開日2025-02-26
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insight into the subclass B1 metallo-beta-lactamase AFM-1.
Biochem.Biophys.Res.Commun., 720, 2024
8XH7
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BU of 8xh7 by Molmil
Structure of EBV LMP1 oligomer
分子名称: Latent membrane protein 1
著者Gao, P, Huang, J.F.
登録日2023-12-17
公開日2024-06-26
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Assembly and activation of EBV latent membrane protein 1.
Cell, 187, 2024
8XH6
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BU of 8xh6 by Molmil
Structure of EBV LMP1 dimer
分子名称: Latent membrane protein 1
著者Gao, P, Huang, J.F.
登録日2023-12-17
公開日2024-06-26
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Assembly and activation of EBV latent membrane protein 1.
Cell, 187, 2024
8ZFZ
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BU of 8zfz by Molmil
cryo-EM structure of Gs-coupled zebrafish GPR4 at pH 6.5
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Ma, Y, Tang, M, Ru, H, Song, G.
登録日2024-05-08
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of an activated GPR4-Gs signaling complex.
Nat Commun, 16, 2025
7VCP
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BU of 7vcp by Molmil
Frischella perrara beta-fructofuranosidase in complex with fructose
分子名称: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Sucrose-6-phosphate hydrolase, ...
著者Tonozuka, T.
登録日2021-09-03
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enzymatic and structural characterization of beta-fructofuranosidase from the honeybee gut bacterium Frischella perrara.
Appl.Microbiol.Biotechnol., 106, 2022
7VCO
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BU of 7vco by Molmil
Frischella perrara beta-fructofuranosidase
分子名称: DI(HYDROXYETHYL)ETHER, Sucrose-6-phosphate hydrolase, TRIETHYLENE GLYCOL
著者Tonozuka, T.
登録日2021-09-03
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Enzymatic and structural characterization of beta-fructofuranosidase from the honeybee gut bacterium Frischella perrara.
Appl.Microbiol.Biotechnol., 106, 2022
7UN5
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BU of 7un5 by Molmil
Structure of Type II Prion filaments from Gerstmann-Straussler-Scheinker disease
分子名称: Major prion protein
著者Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
登録日2022-04-08
公開日2022-07-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7UMQ
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BU of 7umq by Molmil
Structure of Type I Prion filaments from Gerstmann-Straussler-Scheinker disease
分子名称: Major prion protein
著者Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
登録日2022-04-07
公開日2022-07-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7V48
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BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V47
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BU of 7v47 by Molmil
Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V49
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Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7CKI
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BU of 7cki by Molmil
Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP
分子名称: (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lyu, G, Fan, S, Jin, Y, Liu, J, Zou, S, Wu, G, Yang, Z.
登録日2020-07-17
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP
To Be Published
7DRK
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BU of 7drk by Molmil
Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ...
著者Yang, B.W, Liu, Z.F.
登録日2020-12-28
公開日2021-12-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.
Curr Res Struct Biol, 3, 2021
7DRJ
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Crystal structure of phosphatidylglycerol phosphate synthase in complex with phosphatidylglycerol phosphate
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, ACETIC ACID, ...
著者Yang, B.W, Liu, Z.F.
登録日2020-12-28
公開日2021-12-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.
Curr Res Struct Biol, 3, 2021
7C1D
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BU of 7c1d by Molmil
Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Zhao, K, Liu, C.
登録日2020-05-03
公開日2021-05-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EG4
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Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex
分子名称: MAGNESIUM ION, Parvine, Schlafen family member 12, ...
著者Liu, N, Chen, J, Wang, X.D, Wang, H.W.
登録日2021-03-24
公開日2021-09-29
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells.
Nat Commun, 12, 2021

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