Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8W2Q
DownloadVisualize
BU of 8w2q by Molmil
BsaXI-DNA complex II
分子名称: DNA (41-MER), RM.BsaXI, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Shen, B.W, Stoddard, B.L, Xu, S.
登録日2024-02-21
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural and biochemical analysis of subunit assembly, DNA recognition and cleavage by a Type IIB restriction-modification enzyme: BsaXI
To Be Published
5BYO
DownloadVisualize
BU of 5byo by Molmil
Computationally designed left-handed alpha/alpha toroid with 12 repeats
分子名称: dTor_12x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-06-10
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
299D
DownloadVisualize
BU of 299d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: THE HAMMERHEAD RIBOZYME
分子名称: RNA HAMMERHEAD RIBOZYME
著者Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
登録日1996-12-14
公開日1997-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
1QVJ
DownloadVisualize
BU of 1qvj by Molmil
structure of NUDT9 complexed with ribose-5-phosphate
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-O-phosphono-beta-D-ribofuranose, ADP-ribose pyrophosphatase, ...
著者Shen, B.W, Perraud, A.-L, Scharenberg, A.S, Stoddard, B.L.
登録日2003-08-27
公開日2003-09-16
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The crystal structure and mutational analysis of human NUDT9
J.Mol.Biol., 332, 2003
6UVW
DownloadVisualize
BU of 6uvw by Molmil
Engineered variant of I-OnuI meganuclease with improved thermostability
分子名称: CALCIUM ION, DNA (27-MER), I-OnuI-e-Therm
著者Werther, R, Stoddard, B.L.
登録日2019-11-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
6UWK
DownloadVisualize
BU of 6uwk by Molmil
Engineered variant of I-OnuI meganuclease with improved stability and fully altered specificity targeting human chromosome 11 trans integration site
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (27-MER), ...
著者Werther, R, Stoddard, B.L.
登録日2019-11-05
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.533 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
6UWH
DownloadVisualize
BU of 6uwh by Molmil
Intermediate engineered variant of I-OnuI meganuclease with improved thermostability and partially altered specificity
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (26-MER), ...
著者Werther, R, Stoddard, B.L.
登録日2019-11-05
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
6UW0
DownloadVisualize
BU of 6uw0 by Molmil
Engineered variant of I-OnuI meganuclease with improved thermostability and fully altered specificity targeting cholera toxin A subunit
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (27-MER), ...
著者Werther, R, Stoddard, B.L.
登録日2019-11-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
6UWG
DownloadVisualize
BU of 6uwg by Molmil
Engineered variant of I-OnuI meganuclease with improved thermostability and E178D mutation at catalytic site
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (26-MER), ...
著者Werther, R, Stoddard, B.L.
登録日2019-11-05
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
6UWJ
DownloadVisualize
BU of 6uwj by Molmil
Intermediate engineered variant of I-OnuI meganuclease with improved thermostability and partially altered specificity
分子名称: CALCIUM ION, DNA (27-MER), I-OnuI-e-Therm-hChr11v2
著者Werther, R, Stoddard, B.L.
登録日2019-11-05
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Structure, 28, 2020
301D
DownloadVisualize
BU of 301d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED
分子名称: MAGNESIUM ION, RNA HAMMERHEAD RIBOZYME
著者Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
登録日1996-12-14
公開日1997-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
2ERH
DownloadVisualize
BU of 2erh by Molmil
Crystal Structure of the E7_G/Im7_G complex; a designed interface between the colicin E7 DNAse and the Im7 immunity protein
分子名称: Colicin E7, Colicin E7 immunity protein
著者Joachimiak, L.A, Kortemme, T, Stoddard, B.L, Baker, D.
登録日2005-10-24
公開日2006-07-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein-Protein Interface.
J.Mol.Biol., 361, 2006
5ESP
DownloadVisualize
BU of 5esp by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-PanMI with coordinated Calcium ions
分子名称: CALCIUM ION, DNA (27-MER), GLYCEROL, ...
著者Hallinan, J.P, Stoddard, B.L.
登録日2015-11-16
公開日2016-03-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.995 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
300D
DownloadVisualize
BU of 300d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MN(II)-SOAKED
分子名称: MANGANESE (II) ION, RNA HAMMERHEAD RIBOZYME
著者Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
登録日1996-12-14
公開日1997-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
3BVQ
DownloadVisualize
BU of 3bvq by Molmil
Crystal Structure of Apo NotI Restriction Endonuclease
分子名称: FE (III) ION, NotI restriction endonuclease, SULFATE ION
著者Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L.
登録日2008-01-07
公開日2008-01-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Structure, 16, 2008
3C25
DownloadVisualize
BU of 3c25 by Molmil
Crystal Structure of NotI Restriction Endonuclease Bound to Cognate DNA
分子名称: CALCIUM ION, DNA (5'-D(*DCP*DGP*DGP*DAP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DTP*DCP*DCP*DG)-3'), ...
著者Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L.
登録日2008-01-24
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Structure, 16, 2008
2EX5
DownloadVisualize
BU of 2ex5 by Molmil
Group I Intron-encoded Homing Endonuclease I-CeuI Complexed With DNA
分子名称: CALCIUM ION, DNA endonuclease I-CeuI, I-CeuI DNA target site, ...
著者Spiegel, P.C, Stoddard, B.L.
登録日2005-11-07
公開日2006-05-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold.
Structure, 14, 2006
2FLD
DownloadVisualize
BU of 2fld by Molmil
I-MsoI Re-Designed for Altered DNA Cleavage Specificity
分子名称: 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ...
著者Ashworth, J, Duarte, C.M, Havranek, J.J, Sussman, D, Monnat, R.J, Stoddard, B.L, Baker, D.
登録日2006-01-05
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006
6MAF
DownloadVisualize
BU of 6maf by Molmil
native BbvCI A2B2 tetramer at low resolution
分子名称: BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-27
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
2OST
DownloadVisualize
BU of 2ost by Molmil
The structure of a bacterial homing endonuclease : I-Ssp6803I
分子名称: CALCIUM ION, Putative endonuclease, Synthetic DNA 29 MER
著者Zhao, L, Bonocora, R.P, Shub, D.A, Stoddard, B.L.
登録日2007-02-06
公開日2007-03-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The restriction fold turns to the dark side: a bacterial homing endonuclease with a PD-(D/E)-XK motif.
Embo J., 26, 2007
1IDE
DownloadVisualize
BU of 1ide by Molmil
ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)
分子名称: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION, ...
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
6M9G
DownloadVisualize
BU of 6m9g by Molmil
BbvCI B2 dimer with Ta6Br14 clusters
分子名称: 1,2-ETHANEDIOL, ACETATE ION, BROMIDE ION, ...
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-23
公開日2018-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
6MAG
DownloadVisualize
BU of 6mag by Molmil
native BbvCI B2 dimer in space group C222
分子名称: ACETATE ION, BbvCI endonuclease subunit 2, GLYCEROL, ...
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-27
公開日2018-11-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
2O6M
DownloadVisualize
BU of 2o6m by Molmil
H98Q mutant of the homing endonuclease I-PPOI complexed with DNA
分子名称: 5'-D(*DTP*DTP*DGP*DAP*DCP*DTP*DCP*DTP*DCP*DTP*DTP*DAP*DAP*DGP*DAP*DGP*DAP*DGP*DTP*DCP*DA)-3', Intron-encoded endonuclease I-PpoI, MAGNESIUM ION, ...
著者Eastberg, J.H, Stoddard, B.L.
登録日2006-12-07
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutability of an HNH nuclease imidazole general base and exchange of a deprotonation mechanism.
Biochemistry, 46, 2007
7RDR
DownloadVisualize
BU of 7rdr by Molmil
Circular tandem repeat protein with novel repeat topology and enhanced subunit contact surfaces
分子名称: Circular tendon repeat protein
著者Shen, B.W, Stoddard, B.L.
登録日2021-07-10
公開日2021-09-01
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon