2ERH

Crystal Structure of the E7_G/Im7_G complex; a designed interface between the colicin E7 DNAse and the Im7 immunity protein

Summary for 2ERH

Entry DOI	10.2210/pdb2erh/pdb
Related	7CEI
Descriptor	Colicin E7 immunity protein, Colicin E7 (3 entities in total)
Functional Keywords	computational design, redesigned protein-protein interface, hydrogen bond network, specificity, molecular recognition, protein complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	24626.58
Authors	Joachimiak, L.A.,Kortemme, T.,Stoddard, B.L.,Baker, D. (deposition date: 2005-10-24, release date: 2006-07-25, Last modification date: 2023-08-23)
Primary citation	Joachimiak, L.A.,Kortemme, T.,Stoddard, B.L.,Baker, D. Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein-Protein Interface. J.Mol.Biol., 361:195-208, 2006 Cited by PubMed: 16831445 DOI: 10.1016/j.jmb.2006.05.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation