4PQK
 
 | | C-Terminal domain of DNA binding protein | | 分子名称: | Maltose ABC transporter periplasmic protein, Truncated replication protein RepA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Schumacher, M.A, Chinnam, N, Tonthat, N.K. | | 登録日 | 2014-03-03 | | 公開日 | 2014-06-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | | 主引用文献 | Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4PT7
 | | Structure of initiator | | 分子名称: | Replication initiator A family protein, SULFATE ION | | 著者 | Schumacher, M.A. | | 登録日 | 2014-03-10 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4PQL
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4LSD
 | | Myokine structure | | 分子名称: | Fibronectin type III domain-containing protein 5 | | 著者 | Schumacher, M.A, Ohashi, T, Shah, R.S, Chinnam, N, Erickson, H. | | 登録日 | 2013-07-22 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | The structure of irisin reveals a novel intersubunit beta-sheet fibronectin type III (FNIII) dimer: implications for receptor activation.
J.Biol.Chem., 288, 2013
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6U9X
 | | Structure of T. brucei MERS1-RNA complex | | 分子名称: | Mitochondrial edited mRNA stability factor 1, RNA (5'-R(*GP*AP*GP*AP*GP*GP*GP*GP*GP*UP*U)-3') | | 著者 | Schumacher, M.A. | | 登録日 | 2019-09-09 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei.
Rna, 26, 2020
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6UMK
 | | Structure of E. coli FtsZ(L178E)-GDP complex | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Schumacher, M.A. | | 登録日 | 2019-10-09 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP.
Acta Crystallogr.,Sect.F, 76, 2020
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6UNX
 | | Structure of E. coli FtsZ(L178E)-GTP complex | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Schumacher, M.A. | | 登録日 | 2019-10-13 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP.
Acta Crystallogr.,Sect.F, 76, 2020
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3HZI
 | | Structure of mdt protein | | 分子名称: | 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ... | | 著者 | Schumacher, M.A. | | 登録日 | 2009-06-23 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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5TZF
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1 | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | 著者 | Schumacher, M.A. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5TZG
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2 | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION | | 著者 | Schumacher, M.A. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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7U3A
 | | Structure of the Streptomyces venezuelae GlgX-c-di-GMP complex | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | | 著者 | Schumacher, M.A. | | 登録日 | 2022-02-26 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | | 主引用文献 | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
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7U3D
 | | Structure of S. venezuelae GlgX-c-di-GMP-acarbose complex (4.6) | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | | 著者 | Schumacher, M.A. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
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7U3B
 | | Structure of S. venezuelae GlgX bound to c-di-GMP and acarbose (pH 8.5) | | 分子名称: | 4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranosyl)-beta-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX, ... | | 著者 | Schumacher, M.A, Tschowri, N. | | 登録日 | 2022-02-26 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
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7U39
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2G66
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2GIA
 | | Crystal structures of trypanosoma bruciei MRP1/MRP2 | | 分子名称: | ACETIC ACID, mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 | | 著者 | Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. | | 登録日 | 2006-03-28 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
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2GID
 | | Crystal structures of trypanosoma bruciei MRP1/MRP2 | | 分子名称: | mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 | | 著者 | Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. | | 登録日 | 2006-03-28 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
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2GJE
 | | Structure of a guideRNA-binding protein complex bound to a gRNA | | 分子名称: | RNA tetramer, guide RNA 40-mer, mitochondrial RNA-binding protein 1, ... | | 著者 | Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. | | 登録日 | 2006-03-30 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
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1UPF
 | | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL | | 分子名称: | 5-FLUOROURACIL, SULFATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE | | 著者 | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | | 登録日 | 1998-06-17 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
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1LII
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE 2 AND AMP-PCP | | 分子名称: | ADENOSINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIJ
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP | | 分子名称: | 2-RIBOFURANOSYL-3-IODO-2,3-DIHYDRO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIK
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE | | 分子名称: | ADENOSINE, CHLORIDE ION, SULFATE ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIO
 | | STRUCTURE OF APO T. GONDII ADENOSINE KINASE | | 分子名称: | adenosine kinase | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-06-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1KQ2
 | | Crystal Structure of an Hfq-RNA Complex | | 分子名称: | 5'-R(*AP*UP*UP*UP*UP*UP*G)-3', Host factor for Q beta | | 著者 | Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G. | | 登録日 | 2002-01-03 | | 公開日 | 2002-07-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
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1UPU
 | | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP) | | 分子名称: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE | | 著者 | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | | 登録日 | 1998-04-16 | | 公開日 | 1999-05-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
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