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6DDY
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BU of 6ddy by Molmil
Crystal structure of the double mutant (D52N/K359Q) of NT5C2-537X in the active state, Northeast Structural Genomics Target
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2018-05-10
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018
6DDX
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BU of 6ddx by Molmil
Crystal structure of the double mutant (D52N/L375F) of NT5C2-537X in the active state, Northeast Structural Genomics Target
分子名称: Cytosolic purine 5'-nucleotidase, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2018-05-10
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018
6DDB
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BU of 6ddb by Molmil
Crystal structure of the double mutant (D52N/R367Q) of NT5C2-537X in the basal state, Northeast Structural Genomics Consortium Target
分子名称: Cytosolic purine 5'-nucleotidase, MANGANESE (II) ION, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2018-05-09
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018
6DDQ
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BU of 6ddq by Molmil
Crystal structure of the double mutant (R39Q/D52N) of the full-length NT5C2 in the basal state
分子名称: 1,2-ETHANEDIOL, Cytosolic purine 5'-nucleotidase, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L.
登録日2018-05-10
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018
2LVH
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BU of 2lvh by Molmil
Solution structure of the zinc finger AFV1p06 protein from the hyperthermophilic archaeal virus AFV1
分子名称: Putative zinc finger protein ORF59a, ZINC ION
著者Guilliere, F, Sezonov, G, Prangishvili, D, Delepierre, M, Guijarro, J.
登録日2012-07-05
公開日2013-01-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold.
Plos One, 8, 2013
2KEL
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BU of 2kel by Molmil
Structure of the transcription regulator SvtR from the hyperthermophilic archaeal virus SIRV1
分子名称: Uncharacterized protein 56B
著者Guilliere, F, Kessler, A, Peixeiro, N, Sezonov, G, Prangishvili, D, Delepierre, M, Guijarro, J.I.
登録日2009-01-30
公開日2009-06-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1.
J.Biol.Chem., 284, 2009
6WO9
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BU of 6wo9 by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 1-diphosphoinositol pentakisphosphate (1-IP7) and Mg
分子名称: (1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOI
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BU of 6woi by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 1-Diphosphoinositol pentakisphosphate, Mg, and Fluoride ion, presoaked with 1,5-IP8, Mg and Fluoride for 30 seconds
分子名称: (1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOG
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BU of 6wog by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-methylenebisphosphonate inositol pentakisphosphate (5-PCP-IP5)
分子名称: Diphosphoinositol polyphosphate phosphohydrolase 1, Methylenebisphosphonate inositol pentakisphosphate, SULFATE ION
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOE
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BU of 6woe by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with inositol hexakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 10min in the absence of Fluoride.
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WO7
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BU of 6wo7 by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-Diphosphoinositol pentakisphosphate (5-IP7), Mg, and Fluoride ion
分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WO8
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BU of 6wo8 by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5-PP-IP4), Mg, and Fluoride ion
分子名称: (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOA
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BU of 6woa by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 2-Diphosphoinositol pentakisphosphate (2-IP7), Mg, and Fluoride ion
分子名称: (1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOD
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BU of 6wod by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with inositol hexakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 2min in the absence of Fluoride.
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOF
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BU of 6wof by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with inositol hexakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 20min in the absence of Fluoride.
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOB
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BU of 6wob by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 4-diphosphoinositol pentakisphosphate (4-IP7), Mg, and Fluoride ion
分子名称: (1S,2R,3S,4S,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, B.S.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOC
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BU of 6woc by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol pentakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 1min in the absence of Fluoride.
分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
6WOH
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BU of 6woh by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 1,5-di-methylenebisphosphonate inositol tetrakisphosphate (1,5-PCP-IP4)
分子名称: Diphosphoinositol polyphosphate phosphohydrolase 1, SULFATE ION, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid)
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
1D78
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BU of 1d78 by Molmil
HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION
分子名称: DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3')
著者Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M.
登録日1992-06-12
公開日1993-04-15
最終更新日2023-03-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A.
Acta Crystallogr.,Sect.D, 49, 1993
1D42
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BU of 1d42 by Molmil
SOLUTION STRUCTURE OF [D(GTATATAC)]2 VIA RESTRAINED MOLECULAR DYNAMICS SIMULATIONS WITH NUCLEAR MAGNETIC RESONANCE CONSTRAINTS DERIVED FROM RELAXATION MATRIX ANALYSIS OF TWO-DIMENSIONAL NUCLEAR OVERHAUSER EFFECT EXPERIMENTS
分子名称: DNA (5'-D(*GP*TP*AP*TP*AP*TP*AP*C)-3')
著者Schmitz, U, James, T.L.
登録日1991-05-15
公開日1993-04-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of [d(GTATATAC)]2 via restrained molecular dynamics simulations with nuclear magnetic resonance constraints derived from relaxation matrix analysis of two-dimensional nuclear Overhauser effect experiments.
J.Mol.Biol., 221, 1991
1D79
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BU of 1d79 by Molmil
HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION
分子名称: DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3')
著者Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M.
登録日1992-06-12
公開日1993-04-15
最終更新日2023-03-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A.
Acta Crystallogr.,Sect.D, 49, 1993
1XKM
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BU of 1xkm by Molmil
NMR structure of antimicrobial peptide distinctin in water
分子名称: Distinctin chain A, Distinctin chain B
著者Amodeo, P, Raimondo, D, Andreotti, G, Motta, A, Scaloni, A.
登録日2004-09-29
公開日2005-04-05
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin.
Proc.Natl.Acad.Sci.Usa, 102, 2005
8G9E
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BU of 8g9e by Molmil
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMP-PNP and 5-(PCF2P)-IP5, an analog of 5-IP7
分子名称: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wang, H, Shears, S.B.
登録日2023-02-21
公開日2024-01-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs.
Chemistry, 29, 2023
6X5H
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Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP
分子名称: 1,2-ETHANEDIOL, Alpha-(1,6)-fucosyltransferase, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
6X5S
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Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3'-Asn
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A3'-Asn, Alpha-(1,6)-fucosyltransferase, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020

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