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6MDW
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BU of 6mdw by Molmil
Mechanism of protease dependent DPC repair
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ...
著者Li, F, Raczynska, J, Chen, Z, Yu, H.
登録日2018-09-05
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
6WG3
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BU of 6wg3 by Molmil
Cryo-EM structure of human Cohesin-NIPBL-DNA complex
分子名称: Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ...
著者Shi, Z.B, Gao, H, Bai, X.C, Yu, H.
登録日2020-04-04
公開日2020-05-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WGE
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BU of 6wge by Molmil
Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1
分子名称: DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ...
著者Shi, Z.B, Gao, H, Bai, X.C, Yu, H.
登録日2020-04-05
公開日2020-05-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WG4
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BU of 6wg4 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation
分子名称: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3
著者Shi, Z.B, Yu, H.
登録日2020-04-04
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WSL
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BU of 6wsl by Molmil
Cryo-EM structure of VASH1-SVBP bound to microtubules
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Small vasohibin-binding protein, ...
著者Li, F, Li, Y, Yu, H.
登録日2020-05-01
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of VASH1-SVBP bound to microtubules.
Elife, 9, 2020
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Kikuchi, S, Choi, E, Yu, H.
登録日2017-11-17
公開日2018-11-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
6WG6
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BU of 6wg6 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in north-open conformation
分子名称: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3, poly(dT)
著者Shi, Z.B, Yu, H.
登録日2020-04-04
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
5T8V
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BU of 5t8v by Molmil
Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment
分子名称: CITRIC ACID, Putative uncharacterized protein
著者Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z.
登録日2016-09-08
公開日2016-10-19
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
Proc.Natl.Acad.Sci.USA, 113, 2016
4K6J
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BU of 4k6j by Molmil
Human cohesin inhibitor WapL
分子名称: ACETATE ION, SULFATE ION, Wings apart-like protein homolog
著者Tomchick, D.R, Yu, H, Ouyang, Z.
登録日2013-04-16
公開日2013-06-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6205 Å)
主引用文献Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013
3SHU
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BU of 3shu by Molmil
Crystal structure of ZO-1 PDZ3
分子名称: Tight junction protein ZO-1
著者Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
登録日2011-06-17
公開日2011-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3SHW
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BU of 3shw by Molmil
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
分子名称: Gap junction gamma-1 protein, Tight junction protein ZO-1
著者Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
登録日2011-06-17
公開日2011-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3GMH
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BU of 3gmh by Molmil
Crystal Structure of the Mad2 Dimer
分子名称: Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION
著者Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J.
登録日2009-03-13
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
Proc.Natl.Acad.Sci.USA, 112, 2015
1DUJ
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BU of 1duj by Molmil
SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2
分子名称: SPINDLE ASSEMBLY CHECKPOINT PROTEIN
著者Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H.
登録日2000-01-17
公開日2000-03-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
5UN0
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BU of 5un0 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125
分子名称: proteasome assembly chaperone 2 (PAC2) homologue Rv2125
著者Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H.
登録日2017-01-30
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).
J. Bacteriol., 199, 2017
3Q6S
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BU of 3q6s by Molmil
The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
分子名称: Chromobox protein homolog 1, Shugoshin-like 1
著者Brautigam, C.A, Chaudhary, J, Yu, H.
登録日2011-01-03
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
6OCF
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BU of 6ocf by Molmil
The crystal structure of VASH1-SVBP complex
分子名称: CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
6OCH
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BU of 6och by Molmil
Crystal structure of VASH1-SVBP complex bound with parthenolide
分子名称: GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
4FTW
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BU of 4ftw by Molmil
Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution
分子名称: 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ...
著者Wu, L, Ma, J, Zhou, J, Yu, H.
登録日2012-06-28
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
1KLQ
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BU of 1klq by Molmil
The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20
分子名称: MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide
著者Luo, X, Tang, Z, Rizo, J, Yu, H.
登録日2001-12-12
公開日2002-01-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.
Mol.Cell, 9, 2002
3DWA
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BU of 3dwa by Molmil
Crystal structure of the B-subunit of the AB5 toxin from E. coli
分子名称: PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B
著者Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
登録日2008-07-22
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.084 Å)
主引用文献Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWP
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BU of 3dwp by Molmil
Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc
分子名称: N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ...
著者Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
登録日2008-07-22
公開日2008-11-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWQ
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BU of 3dwq by Molmil
Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc
分子名称: AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ...
著者Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
登録日2008-07-22
公開日2008-11-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
6OCG
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BU of 6ocg by Molmil
Crystal structure of VASH1-SVBP complex bound with EpoY
分子名称: CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.833 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
6MDX
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BU of 6mdx by Molmil
Mechanism of protease dependent DPC repair
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, DNA (5'-D(P*CP*C)-3'), ...
著者Li, F, Raczynska, J, Chen, Z, Yu, H.
登録日2018-09-05
公開日2019-04-10
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
4PJW
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BU of 4pjw by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
著者Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
登録日2014-05-12
公開日2014-08-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014

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