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2VFX
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BU of 2vfx by Molmil
Structure of the Symmetric Mad2 Dimer
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
著者Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X.
登録日2007-11-05
公開日2008-03-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
2UXN
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BU of 2uxn by Molmil
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
分子名称: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H.
登録日2007-03-28
公開日2007-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
2UXX
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BU of 2uxx by Molmil
Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct
分子名称: CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ...
著者Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H.
登録日2007-03-30
公開日2007-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
3SHW
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BU of 3shw by Molmil
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
分子名称: Gap junction gamma-1 protein, Tight junction protein ZO-1
著者Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
登録日2011-06-17
公開日2011-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
1PKT
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BU of 1pkt by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
著者Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
登録日1994-03-07
公開日1994-05-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
3SHU
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BU of 3shu by Molmil
Crystal structure of ZO-1 PDZ3
分子名称: Tight junction protein ZO-1
著者Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
登録日2011-06-17
公開日2011-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3Q6S
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BU of 3q6s by Molmil
The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
分子名称: Chromobox protein homolog 1, Shugoshin-like 1
著者Brautigam, C.A, Chaudhary, J, Yu, H.
登録日2011-01-03
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
1PKS
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BU of 1pks by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
著者Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
登録日1994-03-07
公開日1994-05-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
3GMH
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BU of 3gmh by Molmil
Crystal Structure of the Mad2 Dimer
分子名称: Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION
著者Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J.
登録日2009-03-13
公開日2010-11-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
Proc.Natl.Acad.Sci.USA, 112, 2015
4K6J
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BU of 4k6j by Molmil
Human cohesin inhibitor WapL
分子名称: ACETATE ION, SULFATE ION, Wings apart-like protein homolog
著者Tomchick, D.R, Yu, H, Ouyang, Z.
登録日2013-04-16
公開日2013-06-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6205 Å)
主引用文献Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013
1DUJ
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BU of 1duj by Molmil
SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2
分子名称: SPINDLE ASSEMBLY CHECKPOINT PROTEIN
著者Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H.
登録日2000-01-17
公開日2000-03-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
4PJW
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BU of 4pjw by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
著者Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
登録日2014-05-12
公開日2014-08-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
6OCF
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BU of 6ocf by Molmil
The crystal structure of VASH1-SVBP complex
分子名称: CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
6OCH
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BU of 6och by Molmil
Crystal structure of VASH1-SVBP complex bound with parthenolide
分子名称: GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
6OCG
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BU of 6ocg by Molmil
Crystal structure of VASH1-SVBP complex bound with EpoY
分子名称: CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ...
著者Li, F, Luo, X, Yu, H.
登録日2019-03-23
公開日2019-06-26
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.833 Å)
主引用文献Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
5UN0
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BU of 5un0 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125
分子名称: proteasome assembly chaperone 2 (PAC2) homologue Rv2125
著者Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H.
登録日2017-01-30
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).
J. Bacteriol., 199, 2017
4PJU
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BU of 4pju by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1)
分子名称: Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
著者Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
登録日2014-05-12
公開日2014-08-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
4PK7
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BU of 4pk7 by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
著者Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
登録日2014-05-13
公開日2014-09-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Kikuchi, S, Choi, E, Yu, H.
登録日2017-11-17
公開日2018-11-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
1KLQ
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BU of 1klq by Molmil
The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20
分子名称: MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide
著者Luo, X, Tang, Z, Rizo, J, Yu, H.
登録日2001-12-12
公開日2002-01-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.
Mol.Cell, 9, 2002
4N14
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BU of 4n14 by Molmil
Crystal structure of Cdc20 and apcin complex
分子名称: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog
著者Luo, X, Tian, W, Yu, H.
登録日2013-10-03
公開日2014-08-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
Nature, 514, 2014
5JB1
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BU of 5jb1 by Molmil
Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle
分子名称: Major capsid protein L1
著者Li, Z.H, Yan, X.D, Yu, H, Zheng, Q.B, Gu, Y, Li, S.W.
登録日2016-04-13
公開日2016-05-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
7VCU
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BU of 7vcu by Molmil
Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCT
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BU of 7vct by Molmil
Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCX
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BU of 7vcx by Molmil
Human p97 single hexamer conformer II with ATPgammaS bound
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022

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