7YIM
 
 | | Cryo-EM structure of human Alpha-fetoprotein | | 分子名称: | Alpha-fetoprotein | | 著者 | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
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8HRU
 | | Cryo-EM structure of ACE2 | | 分子名称: | Angiotensin-converting enzyme 2 | | 著者 | Xu, J, Liu, N, Wang, H.W. | | 登録日 | 2022-12-16 | | 公開日 | 2023-12-20 | | 最終更新日 | 2025-01-01 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRI
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8HRM
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8HRK
 | | SARS-CoV-2 Delta S-RBD-ACE2 complex | | 分子名称: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Xu, J, Meng, F, Liu, N, Wang, H.W. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-20 | | 最終更新日 | 2025-01-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRN
 | | Cryo-EM structure of ACE2 | | 分子名称: | Angiotensin-converting enzyme 2 | | 著者 | Xu, J, Liu, N, Wang, H.W. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-20 | | 最終更新日 | 2025-01-01 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRL
 | | SARS-CoV-2 Delta S-RBD-ACE2 | | 分子名称: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Xu, J, Meng, F, Liu, N, Wang, H.W. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-20 | | 最終更新日 | 2025-01-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRJ
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7EJE
 | | human RAD51 post-synaptic complex | | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, ... | | 著者 | Zhao, L.Y, Xu, J.F, Wang, H.W. | | 登録日 | 2021-04-02 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination.
Nucleic Acids Res., 49, 2021
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8JWH
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6K41
 | | cryo-EM structure of alpha2BAR-GoA complex | | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | | 登録日 | 2019-05-23 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine.
Nat.Chem.Biol., 16, 2020
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7XGY
 | | cryo-EM structure of hemoglobin | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Liu, N, Wang, H.W. | | 登録日 | 2022-04-07 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
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6K42
 | | cryo-EM structure of alpha2BAR-Gi1 complex | | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | | 登録日 | 2019-05-23 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine.
Nat.Chem.Biol., 16, 2020
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5GRS
 | | Complex structure of the fission yeast SREBP-SCAP binding domains | | 分子名称: | Sterol regulatory element-binding protein 1, Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Gong, X, Qian, H.W, Wu, J.P, Yan, N. | | 登録日 | 2016-08-12 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Cell Res., 26, 2016
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5GPD
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5XMI
 | | Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4 | | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | | 登録日 | 2017-05-15 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
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4Z0C
 | | Crystal structure of TLR13-ssRNA13 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-R(P*AP*CP*GP*GP*AP*AP*AP*GP*AP*CP*CP*CP*C)-3'), ... | | 著者 | Song, W, Han, Z, Chai, J. | | 登録日 | 2015-03-26 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13
Nat.Struct.Mol.Biol., 22, 2015
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5G2X
 | | Structure a of Group II Intron Complexed with its Reverse Transcriptase | | 分子名称: | 5'-R(*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*CP)-3', GROUP II INTRON, GROUP II INTRON-ENCODED PROTEIN LTRA | | 著者 | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | | 登録日 | 2016-04-16 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of a Group II Intron in Complex with its Reverse Transcriptase.
Nat.Struct.Mol.Biol., 23, 2016
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5G2Y
 | | Structure a of Group II Intron Complexed with its Reverse Transcriptase | | 分子名称: | GROUP II INTRON | | 著者 | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | | 登録日 | 2016-04-16 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of a Group II Intron in Complex with its Reverse Transcriptase.
Nat.Struct.Mol.Biol., 23, 2016
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5H64
 | | Cryo-EM structure of mTORC1 | | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | | 登録日 | 2016-11-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
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7C8D
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7CZP
 | | S protein of SARS-CoV-2 in complex bound with P2B-1A1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c181_light_IGLV2-14_IGLJ3,IGL@ protein, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZQ
 | | S protein of SARS-CoV-2 in complex bound with P2B-1A10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c642_heavy_IGHV3-53_IGHD1-26_IGHJ6,Chain H of P2B-1A10,Immunoglobulin gamma-1 heavy chain, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZR
 | | S protein of SARS-CoV-2 in complex bound with P5A-1B8_2B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c542_heavy_IGHV3-53_IGHD3-10_IGHJ6,IGH@ protein, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZT
 | | S protein of SARS-CoV-2 in complex bound with P5A-2G9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c689_light_IGLV5-37_IGLJ3,IGL@ protein, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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