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6A3L
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BU of 6a3l by Molmil
Crystal structure of cytochrome c' from Shewanella violacea DSS12
分子名称: Cytochrome c, HEME C
著者Suka, A, Oki, H, Kato, Y, Kawahara, K, Ohkubo, T, Maruno, T, Kobayashi, Y, Fujii, S, Wakai, S, Sambongi, Y.
登録日2018-06-15
公開日2019-06-12
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure.
Extremophiles, 23, 2019
6A3K
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BU of 6a3k by Molmil
Crystal structure of cytochrome c' from Shewanella benthica DB6705
分子名称: Cytochrome c, HEME C, PENTAETHYLENE GLYCOL
著者Suka, A, Oki, H, Kato, Y, Kawahara, K, Ohkubo, T, Maruno, T, Kobayashi, Y, Fujii, S, Wakai, S, Sambongi, Y.
登録日2018-06-15
公開日2019-06-12
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure.
Extremophiles, 23, 2019
1HNR
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BU of 1hnr by Molmil
H-NS (DNA-BINDING DOMAIN)
分子名称: H-NS
著者Shindo, H, Iwaki, T, Ieda, R, Kurumizaka, H, Ueguchi, C, Mizuno, T, Morikawa, S, Nakamura, H, Kuboniwa, H.
登録日1995-04-06
公開日1995-07-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli.
FEBS Lett., 360, 1995
1IRZ
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BU of 1irz by Molmil
Solution structure of ARR10-B belonging to the GARP family of plant Myb-related DNA binding motifs of the Arabidopsis response regulators
分子名称: ARR10-B
著者Yamazaki, T, Katoh, E, Hosoda, K, Mizuno, T.
登録日2001-10-25
公開日2003-02-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular structure of the GARP family of plant Myb-related DNA binding motifs of the Arabidopsis response regulators
PLANT CELL, 14, 2003
1HNS
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BU of 1hns by Molmil
H-NS (DNA-BINDING DOMAIN)
分子名称: H-NS
著者Shindo, H, Iwaki, T, Ieda, R, Kurumizaka, H, Ueguchi, C, Mizuno, T, Morikawa, S, Nakamura, H, Kuboniwa, H.
登録日1995-04-06
公開日1995-07-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli.
FEBS Lett., 360, 1995
4PX6
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BU of 4px6 by Molmil
SYK catalytic domain in complex with a potent pyridopyrimidinone inhibitor
分子名称: 7-{[(1R,2S)-2-aminocyclohexyl]amino}-5-(1H-indol-7-ylamino)pyrido[4,3-d]pyrimidin-4(3H)-one, Tyrosine-protein kinase SYK
著者Lee, C.C.
登録日2014-03-21
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Syk inhibitors with high potency in presence of blood.
Bioorg.Med.Chem.Lett., 24, 2014
4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
分子名称: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
著者Lee, C.C, Spraggon, G.
登録日2015-04-02
公開日2016-02-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
6BI2
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BU of 6bi2 by Molmil
Trastuzumab Fab D185A (Light Chain) Mutant Biotin Conjugation.
分子名称: 1,2-ETHANEDIOL, BIOTIN, Trastuzumab Anti-HER2 Fab Heavy Chain, ...
著者DiDonato, M, Spraggon, G.
登録日2017-10-31
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation.
Chembiochem, 19, 2018
6BHZ
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BU of 6bhz by Molmil
Trastuzumab Fab D185A (Light Chain) Mutant.
分子名称: 1,2-ETHANEDIOL, Trastuzumab Anti-HER2 Fab Heavy Chain, Trastuzumab Anti-HER2 Fab Light Chain D185A
著者DiDonato, M, Spraggon, G.
登録日2017-10-31
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation.
Chembiochem, 19, 2018
6BI0
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BU of 6bi0 by Molmil
Trastuzumab Fab N158A, D185A, K190A (Light Chain) Triple Mutant.
分子名称: 1,2-ETHANEDIOL, Trastuzumab anti-HER2 Fab Heavy Chain, Trastuzumab anti-HER2 Fab Light Chain
著者DiDonato, M, Spraggon, G.
登録日2017-10-31
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation.
Chembiochem, 19, 2018
3UNP
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BU of 3unp by Molmil
Structure of human SUN2 SUN domain
分子名称: ACETYL GROUP, SUN domain-containing protein 2
著者Zhou, Z.C, Greene, M.I.
登録日2011-11-16
公開日2011-12-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope
J.Biol.Chem., 287, 2012
6LFE
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BU of 6lfe by Molmil
Rat-COMT, Nitecapone,SAM and Mg bond
分子名称: 3-(3,4-dihydroxy-5-nitrobenzylidene)pentane-2,4-dione, Catechol O-methyltransferase, DI(HYDROXYETHYL)ETHER, ...
著者Takebe, K, Iijima, H, Suzuki, M.
登録日2019-12-02
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Catechol O-Methyltransferase Complexed with Nitecapone.
Chem Pharm Bull (Tokyo), 68, 2020
4ZY3
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BU of 4zy3 by Molmil
Crystal Structure of Keap1 in Complex with a small chemical compound, K67
分子名称: FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide)
著者Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M.
登録日2015-05-21
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Nat Commun, 7, 2016
8K2N
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BU of 8k2n by Molmil
Crystal structure of Group 4 Monosaccharide-releasing beta-N-acetylgalactosaminidase NgaLy from Lacticaseibacillus yichunensis, apo form
分子名称: Monosaccharide-releasing beta-N-acetylgalactosaminidase
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2J
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BU of 8k2j by Molmil
Crystal structure of Group 3 Oligosaccharide/Monosaccharide-releasing beta-N-acetylgalactosaminidase NgaDssm, apo form
分子名称: Oligosaccharide/Monosaccharide-releasing beta-N-acetylgalactosaminidase, SULFATE ION
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2K
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BU of 8k2k by Molmil
Crystal structure of Group 3 Oligosaccharide/Monosaccharide-releasing beta-N-acetylgalactosaminidase NgaDssm in complex with GalNAc-thiazoline
分子名称: (3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, CHLORIDE ION, GLYCEROL, ...
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2H
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BU of 8k2h by Molmil
Crystal structure of Group 2Oligosaccharide/Monosaccharide-releasing beta-N-acetylhexosaminidase NgaAt from Arabidopsis thaliana in complex with GalNAc-thiazoline
分子名称: (3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2F
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BU of 8k2f by Molmil
Crystal structure of Group 1 oligosaccharide-releasing beta-N-acetylgalactosaminidase NgaCa from Cohnella abietis, apo 1 form
分子名称: MAGNESIUM ION, Oligosaccharide-releasing beta-N-acetylgalactosaminidase
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2I
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BU of 8k2i by Molmil
Crystal structure of Group 2 Oligosaccharide/Monosaccharide-releasing beta-N-acetylhexosaminidase NgaAt from Arabidopsis thaliana in complex with GlcNAc-thiazoline
分子名称: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2M
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BU of 8k2m by Molmil
Crystal structure of Group 4 Monosaccharide-releasing beta-N-acetylgalactosaminidase NgaP2 from Paenibacillus sp. TS12 in complex with GalNAc-thiazoline
分子名称: (3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, BROMIDE ION, Monosaccharide-releasing beta-N-acetylgalactosaminidase
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2L
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BU of 8k2l by Molmil
Crystal structure of Group 4 Monosaccharide-releasing beta-N-acetylgalactosaminidase NgaP2 from Paenibacillus sp. TS12, apo form
分子名称: BROMIDE ION, Monosaccharide-releasing beta-N-acetylgalactosaminidase
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
8K2G
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BU of 8k2g by Molmil
Crystal structure of Group 1 Oligosaccharide-releasing beta-N-acetylgalactosaminidase NgaCa from Cohnella abietis, apo 2 form
分子名称: MAGNESIUM ION, Oligosaccharide-releasing beta-N-acetylgalactosaminidase
著者Sumida, T, Fushinobu, S.
登録日2023-07-12
公開日2024-04-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.
Nat Commun, 15, 2024
2RQR
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BU of 2rqr by Molmil
The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex
分子名称: Engulfment and cell motility protein 1,Dedicator of cytokinesis protein 2
著者Yokoyama, S, Tochio, N, Koshiba, S, Kigawa, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-10-21
公開日2010-10-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
7B7V
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BU of 7b7v by Molmil
Structure of NUDT15 in complex with Acyclovir monophosphate
分子名称: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate, CHLORIDE ION, MAGNESIUM ION, ...
著者Rehling, D, Stenmark, P.
登録日2020-12-11
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir.
Nat Commun, 12, 2021
7BTV
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BU of 7btv by Molmil
Crystal structure of EHMT2 SET domain in complex with compound 5.
分子名称: Histone-lysine N-methyltransferase EHMT2, N~2~-{4-methoxy-3-[3-(pyrrolidin-1-yl)propoxy]phenyl}-N~4~,6-dimethylpyrimidine-2,4-diamine, S-ADENOSYLMETHIONINE, ...
著者Suzuki, M, Mizuno, T, Katayama, K.
登録日2020-04-03
公開日2020-11-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines.
Bioorg.Med.Chem.Lett., 30, 2020

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