6BI2

Trastuzumab Fab D185A (Light Chain) Mutant Biotin Conjugation.

Summary for 6BI2

• Entry DOI: 10.2210/pdb6bi2/pdb
• Related: 6BHZ 6BI0
• Descriptor: Trastuzumab Anti-HER2 Fab Heavy Chain, Trastuzumab Anti-HER2 Fab Light Chain, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: fab, immunoglobulin, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 95744.84

Authors

DiDonato, M.,Spraggon, G. (deposition date: 2017-10-31, release date: 2018-02-14, Last modification date: 2023-10-04)

• Primary citation: Pham, G.H.,Ou, W.,Bursulaya, B.,DiDonato, M.,Herath, A.,Jin, Y.,Hao, X.,Loren, J.,Spraggon, G.,Brock, A.,Uno, T.,Geierstanger, B.H.,Cellitti, S.E.; Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation.; Chembiochem, 19:799-804, 2018; PubMed: 29388367; DOI: 10.1002/cbic.201700611

Experimental method

X-RAY DIFFRACTION (1.801 Å)