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6BI2

Trastuzumab Fab D185A (Light Chain) Mutant Biotin Conjugation.

Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue EDO H 301
ChainResidue
HLEU148
HVAL176
HSER184
HLEU185
HSER186
HHOH425
LTHR178
LHOH433

site_idAC2
Number of Residues7
Detailsbinding site for residue EDO H 302
ChainResidue
HPRO156
HVAL157
HALA175
HLEU185
HHOH452
HHOH474
HGLU155

site_idAC3
Number of Residues9
Detailsbinding site for residue BTN L 301
ChainResidue
HPHE104
LLEU54
LTYR55
LSER56
LASP151
LLYS188
LHIS189
LLYS190
LHOH502

site_idAC4
Number of Residues7
Detailsbinding site for residue EDO L 302
ChainResidue
LPRO119
LTYR186
LASN210
LARG211
LGLY212
LGLU213
LHOH405

site_idAC5
Number of Residues6
Detailsbinding site for residue EDO L 303
ChainResidue
HTYR95
LGLN38
LLYS39
LGLY41
LLYS42
LHOH540

site_idAC6
Number of Residues9
Detailsbinding site for residue EDO I 301
ChainResidue
ILEU148
IVAL176
ISER184
ILEU185
ISER186
IHOH416
IHOH473
MTHR178
MHOH533

site_idAC7
Number of Residues5
Detailsbinding site for residue EDO I 302
ChainResidue
ITRP110
IGLY111
IGLN112
MALA43
MHOH561

site_idAC8
Number of Residues6
Detailsbinding site for residue EDO I 303
ChainResidue
IGLU155
IPRO156
IVAL157
IALA175
ILEU185
IHOH404

site_idAC9
Number of Residues15
Detailsbinding site for Di-peptide BTN M 400 and LYS M 188
ChainResidue
IGLY100
IASP102
IPHE104
IASP108
MLEU54
MTYR55
MSER56
MASP151
MALA184
MALA185
MTYR186
MGLU187
MHIS189
MLYS190
MHOH514

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
HTYR201-HIS207
LTYR192-HIS198

227344

PDB entries from 2024-11-13

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