5YVB
| Structure of CaMKK2 in complex with CKI-011 | 分子名称: | (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
|
|
5YV9
| Structure of CaMKK2 in complex with CKI-009 | 分子名称: | 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
|
|
5YVA
| Structure of CaMKK2 in complex with CKI-010 | 分子名称: | 3-(1H-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2020-06-10 | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
|
|
5YV8
| Structure of CaMKK2 in complex with CKI-002 | 分子名称: | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.927 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
|
|
5YVC
| Structure of CaMKK2 in complex with CKI-012 | 分子名称: | 3-{2,4-dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
|
|
2EH9
| |
4EIW
| Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Yoshida, M, Morikawa, K. | 登録日 | 2012-04-06 | 公開日 | 2012-06-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of the whole cytosolic region of ATP-dependent protease FtsH Mol.Cell, 22, 2006
|
|
5WRK
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
|
|
3CA0
| Sambucus nigra agglutinin II (SNA-II), hexagonal crystal form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Agglutinin II, ... | 著者 | Maveyraud, L, Niwa, H, Guillet, V, Palmer, R.A, Reynolds, C.D, Mourey, L. | 登録日 | 2008-02-19 | 公開日 | 2008-11-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra Proteins, 75, 2009
|
|
5WRM
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
|
|
5WRL
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | 登録日 | 2016-12-02 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.095 Å) | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
|
|
2DHR
| Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FtsH | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | 登録日 | 2006-03-24 | 公開日 | 2006-06-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
|
|
2DI4
| Crystal structure of the FtsH protease domain | 分子名称: | Cell division protein ftsH homolog, MERCURY (II) ION | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | 登録日 | 2006-03-28 | 公開日 | 2006-06-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
|
|
5YLT
| Crystal structure of SET7/9 in complex with a cyproheptadine derivative | 分子名称: | 2-(1-methylpiperidin-4-ylidene)tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-6-ol, GLYCEROL, Histone-lysine N-methyltransferase SETD7, ... | 著者 | Hirano, T, Fujiwara, T, Niwa, H, Hirano, M, Ohira, K, Okazaki, Y, Sato, S, Umehara, T, Maemoto, Y, Ito, A, Yoshida, M, Kagechika, H. | 登録日 | 2017-10-19 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine. ChemMedChem, 13, 2018
|
|
2CXY
| |
2C96
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
|
|
2BJW
| PspF AAA domain | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | 登録日 | 2005-02-08 | 公開日 | 2005-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins Science, 307, 2005
|
|
2C98
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
|
|
2C99
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
|
|
2C9C
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
|
|
2EFL
| Crystal structure of the EFC domain of formin-binding protein 17 | 分子名称: | Formin-binding protein 1 | 著者 | Shimada, A, Niwa, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-23 | 公開日 | 2007-05-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis Cell(Cambridge,Mass.), 129, 2007
|
|
2BJV
| Crystal Structure of PspF(1-275) R168A mutant | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | 登録日 | 2005-02-08 | 公開日 | 2005-03-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins Science, 307, 2005
|
|
2EGR
| |
2EFK
| Crystal structure of the EFC domain of Cdc42-interacting protein 4 | 分子名称: | Cdc42-interacting protein 4 | 著者 | Shimada, A, Niwa, H, Chen, L, Liu, Z.-J, Wang, B.-C, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-23 | 公開日 | 2007-05-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis Cell(Cambridge,Mass.), 129, 2007
|
|
2EGJ
| |