4DM4
 
 | | The conserved domain of yeast Cdc73 | | 分子名称: | Cell division control protein 73 | | 著者 | Chen, H, Shi, N, Gao, Y, Li, X, Niu, L, Teng, M. | | 登録日 | 2012-02-06 | | 公開日 | 2012-08-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold.
Acta Crystallogr.,Sect.D, 68, 2012
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4DT1
 | | Crystal structure of the Psy3-Csm2 complex | | 分子名称: | Chromosome segregation in meiosis protein 2, ETHANOL, Platinum sensitivity protein 3 | | 著者 | Tao, Y, Niu, L, Teng, M. | | 登録日 | 2012-02-20 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Structural analysis of Shu proteins reveals a DNA binding role essential for resisting damage
J.Biol.Chem., 287, 2012
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4FD3
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4OU6
 | | Crystal structure of DnaT84-153-dT10 ssDNA complex form 1 | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1 | | 著者 | Liu, Z, Chen, P, Niu, L, Teng, M, Li, X. | | 登録日 | 2014-02-15 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
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3LKX
 | | Human nac dimerization domain | | 分子名称: | Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3 | | 著者 | Liu, Y, Hu, Y, Li, X, Niu, L, Teng, M. | | 登録日 | 2010-01-28 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of the human nascent polypeptide-associated complex domain reveals a nucleic acid-binding region on the NACA subunit
Biochemistry, 49, 2010
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4N4X
 | | Crystal Structure of the MBP fused human SPLUNC1 (native form) | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein | | 著者 | Ning, F, Wang, C, Niu, L, Chu, H.W, Zhang, G. | | 登録日 | 2013-10-08 | | 公開日 | 2014-09-17 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Lipid ligands of human SPLUNC1
To be Published
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4FMM
 | | Dimeric Sec14 family homolog 3 from Saccharomyces cerevisiae presents some novel features of structure that lead to a surprising "dimer-monomer" state change induced by substrate binding | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphatidylinositol transfer protein PDR16 | | 著者 | Yuan, Y, Zhao, W, Wang, X, Gao, Y, Niu, L, Teng, M. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Dimeric Sfh3 has structural changes in its binding pocket that are associated with a dimer-monomer state transformation induced by substrate binding.
Acta Crystallogr.,Sect.D, 69, 2013
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4OU7
 | | Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1 | | 著者 | Liu, Z, Chen, P, Niu, L, Teng, M, Li, X. | | 登録日 | 2014-02-15 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
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5H4Z
 | | Crystal structure of S202G mutant of human SYT-5 C2A domain | | 分子名称: | CALCIUM ION, CHLORIDE ION, Synaptotagmin-5 | | 著者 | Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L. | | 登録日 | 2016-11-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
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5H4Y
 | | Crystal structure of human synaptotagmin 5 C2A domain | | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-5 | | 著者 | Qiu, X, Gao, Y, Teng, M, Niu, L. | | 登録日 | 2016-11-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
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6J3O
 | | Crystal structure of the human PCAF bromodomain in complex with compound 12 | | 分子名称: | 3-methyl-2-[[(3~{R})-1-methylpiperidin-3-yl]amino]-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2B | | 著者 | Huang, L.Y, Li, H, Li, L.L, Niu, L, Seupel, R, Wu, C.Y, Li, G.B, Yu, Y.M, Brennan, P.E, Yang, S.Y. | | 登録日 | 2019-01-05 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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6J3P
 | | Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n | | 分子名称: | 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A | | 著者 | Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. | | 登録日 | 2019-01-05 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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3P6Y
 | | CF Im25-CF Im68-UGUAA complex | | 分子名称: | 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | 著者 | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | | 登録日 | 2010-10-11 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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3ONJ
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7EWF
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7EWM
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3P5T
 | | CFIm25-CFIm68 complex | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | 著者 | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | | 登録日 | 2010-10-11 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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3MD1
 | | Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1) | | 分子名称: | GLYCEROL, Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 | | 著者 | Li, H, Shi, H, Li, Y, Cui, Y, Niu, L, Teng, M. | | 登録日 | 2010-03-29 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)
To be published
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3OJB
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3ONL
 | | yeast Ent3_ENTH-Vti1p_Habc complex structure | | 分子名称: | Epsin-3, t-SNARE VTI1 | | 著者 | Wang, J, Fang, P, Niu, L, Teng, M. | | 登録日 | 2010-08-29 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
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3ONK
 | | yeast Ent3_ENTH domain | | 分子名称: | Epsin-3 | | 著者 | Wang, J, Fang, P, Niu, L, Teng, M. | | 登録日 | 2010-08-29 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
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3EHR
 | | Crystal Structure of Human Osteoclast Stimulating Factor | | 分子名称: | Osteoclast-stimulating factor 1 | | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | | 登録日 | 2008-09-14 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
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3EHQ
 | | Crystal Structure of Human Osteoclast Stimulating Factor | | 分子名称: | 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 | | 著者 | Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. | | 登録日 | 2008-09-14 | | 公開日 | 2009-08-04 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
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6J71
 | | HuA21-scFv in complex with the extracellular domain(ECD) of HER2 | | 分子名称: | Receptor tyrosine-protein kinase erbB-2, anti-HER2 humanized antibody HuA21, beta-D-mannopyranose, ... | | 著者 | Wang, Z, Guo, G, Cheng, B, Zhu, Z, Niu, L, Zhang, H. | | 登録日 | 2019-01-16 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.918 Å) | | 主引用文献 | Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells.
Acta Crystallogr D Struct Biol, 75, 2019
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8JKA
 | | SP1746 in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, FE (III) ION, SULFATE ION, ... | | 著者 | Jin, Y, Niu, L, Ke, J. | | 登録日 | 2023-06-01 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia.
Structure, 2024
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