3APM
 
 | | Crystal structure of the human SNP PAD4 protein | | 分子名称: | Protein-arginine deiminase type-4 | | 著者 | Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H. | | 登録日 | 2010-10-19 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene
Acta Crystallogr.,Sect.D, 67, 2011
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7YV1
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | | 登録日 | 2022-08-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
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7YUZ
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | | 分子名称: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2022-08-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
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1ODD
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7TQG
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7KDE
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2CUJ
 | | Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like | | 分子名称: | transcriptional adaptor 2-like | | 著者 | Yoneyama, M, Umehara, T, Sato, M, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-26 | | 公開日 | 2005-11-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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2CU7
 | | Solution structure of the SANT domain of human KIAA1915 protein | | 分子名称: | KIAA1915 protein | | 著者 | Yoneyama, M, Umehara, T, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-25 | | 公開日 | 2005-11-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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6LYC
 | | Crystal structure of the NOD SIRPa complex with D4-2 | | 分子名称: | ACETIC ACID, D4-2, SIRPa of the NOD mouse strain | | 著者 | Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. | | 登録日 | 2020-02-14 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy.
Cell Chem Biol, 27, 2020
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6LM0
 | | The crystal structure of cyanorhodopsin (CyR) N2098R from cyanobacteria Calothrix sp. NIES-2098 | | 分子名称: | DECANE, HEXANE, N-OCTANE, ... | | 著者 | Hosaka, T, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2019-12-24 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A unique clade of light-driven proton-pumping rhodopsins evolved in the cyanobacterial lineage.
Sci Rep, 10, 2020
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6LM1
 | | The crystal structure of cyanorhodopsin (CyR) N4075R from cyanobacteria Tolypothrix sp. NIES-4075 | | 分子名称: | DECANE, DODECANE, HEXADECANE, ... | | 著者 | Hosaka, T, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2019-12-24 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A unique clade of light-driven proton-pumping rhodopsins evolved in the cyanobacterial lineage.
Sci Rep, 10, 2020
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8JJS
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2023-05-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
J.Am.Chem.Soc., 145, 2023
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5XS0
 | | Structure of a ssDNA bound to the outer DNA binding site of RAD52 | | 分子名称: | DNA repair protein RAD52 homolog, ssDNA (5'-D(*CP*CP*CP*CP*CP*C)-3'), ssDNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*C)-3'), ... | | 著者 | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | | 登録日 | 2017-06-11 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
iScience, 3, 2018
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8H79
 | | The crystal structure of cyanorhodopsin-II (CyR-II) P7104R from Nodosilinea nodulosa PCC 7104 | | 分子名称: | CHLORIDE ION, HEXADECANE, HEXANE, ... | | 著者 | Hosaka, T, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2022-10-19 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Cyanorhodopsin-II represents a yellow-absorbing proton-pumping rhodopsin clade within cyanobacteria.
Isme J, 18, 2024
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1IDZ
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1IDY
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4J6R
 | | Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ... | | 著者 | Zhou, T, Moquin, S, Kwong, P.D. | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
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4JB9
 | | Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ... | | 著者 | Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D. | | 登録日 | 2013-02-19 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
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2DCE
 | | Solution structure of the SWIRM domain of human KIAA1915 protein | | 分子名称: | KIAA1915 protein | | 著者 | Yoneyama, M, Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-01-06 | | 公開日 | 2006-07-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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3WEX
 | | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | | 著者 | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | 登録日 | 2013-07-16 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
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5GSE
 | | Crystal structure of unusual nucleosome | | 分子名称: | DNA (250-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Kato, D, Osakabe, A, Arimura, Y, Park, S.Y, Kurumizaka, H. | | 登録日 | 2016-08-16 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Science, 356, 2017
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5XRZ
 | | Structure of a ssDNA bound to the inner DNA binding site of RAD52 | | 分子名称: | DNA repair protein RAD52 homolog, POTASSIUM ION, ssDNA (40-MER) | | 著者 | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | | 登録日 | 2017-06-11 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
iScience, 3, 2018
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2RLT
 | | phosphorylated CPI-17 (22-120) | | 分子名称: | Protein phosphatase 1 regulatory subunit 14A | | 著者 | Eto, M. | | 登録日 | 2007-08-11 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor.
Structure, 15, 2007
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