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7U9E
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Pfs230 D1 domain in complex with 230AL-26
分子名称: 230AL-26, Gametocyte surface protein P230, LMIV230-01
著者Tang, W.K, Tolia, N.H.
登録日2022-03-10
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UNB
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BU of 7unb by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ...
著者Hailemariam, S, McLeod, B, Julien, J.-P.
登録日2022-04-10
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
Immunity, 55, 2022
3VJR
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BU of 3vjr by Molmil
Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA
分子名称: Peptidyl-tRNA hydrolase, tRNA CCA-acceptor
著者Ito, K, Murakami, R, Mochizuki, M, Qi, H, Shimizu, Y, Miura, K.I, Ueda, T, Uchiumi, T.
登録日2011-10-28
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase.
Nucleic Acids Res., 40, 2012
7ZXF
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BU of 7zxf by Molmil
Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1
分子名称: 10D8 heavy chain, 10D8 light chain, 85RF45.1 heavy chain, ...
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-20
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.72 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWM
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Pfs48/45 central and C-terminal domains bound to Fab fragments of monoclonal antibody 10D8 and 32F3
分子名称: 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-19
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWF
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Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3
分子名称: 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-19
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.132 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZXG
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Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8
分子名称: 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-20
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWI
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Pfs48/45 C-terminal domain bound to fab fragment of monoclonal antibody 32F3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 32F3 heavy chain, 32F3 light chain, ...
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-19
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
8DFH
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Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
分子名称: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
分子名称: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
分子名称: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8EZL
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BU of 8ezl by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-50
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZM
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BU of 8ezm by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-63
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZK
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BU of 8ezk by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-04
分子名称: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
6AZZ
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BU of 6azz by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
分子名称: 1190 antibody, heavy chain, light chain, ...
著者Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-13
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0E
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BU of 6b0e by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260
分子名称: 1260 antibody, heavy chain, light chain, ...
著者Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-14
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0G
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BU of 6b0g by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
分子名称: 1245 Antibody, Heavy Chain, Light Chain, ...
著者McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-14
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0A
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BU of 6b0a by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269
分子名称: 1269 antibody, heavy chain, light chain, ...
著者Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-14
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B08
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Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276
分子名称: 1276 antibody, heavy chain, light chain, ...
著者Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-14
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0H
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BU of 6b0h by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262
分子名称: 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ...
著者McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
登録日2017-09-14
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
3SIC
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BU of 3sic by Molmil
MOLECULAR RECOGNITION AT THE ACTIVE SITE OF SUBTILISIN BPN': CRYSTALLOGRAPHIC STUDIES USING GENETICALLY ENGINEERED PROTEINACEOUS INHIBITOR SSI (STREPTOMYCES SUBTILISIN INHIBITOR)
分子名称: CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN'
著者Mitsui, Y, Takeuchi, Y, Nakamura, K.T.
登録日1991-08-30
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor).
Protein Eng., 4, 1991
6PHF
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BU of 6phf by Molmil
Pfs25 in complex with the human transmission blocking antibody 2587
分子名称: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ...
著者McLeod, B.R, Julien, J.P.
登録日2019-06-25
公開日2019-10-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHH
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BU of 6phh by Molmil
Unliganded human transmission blocking antibody 2544
分子名称: 2544 Antibody Fab, Heavy Chain, Light Chain, ...
著者McLeod, B.R, Julien, J.P.
登録日2019-06-25
公開日2019-10-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHC
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BU of 6phc by Molmil
Pfs25 in complex with the human transmission blocking antibody 2544
分子名称: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ...
著者McLeod, B.R, Julien, J.P.
登録日2019-06-25
公開日2019-10-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHB
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Pfs25 in complex with the human transmission blocking antibody 2530
分子名称: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ...
著者McLeod, B.R, Julien, J.P.
登録日2019-06-25
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019

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