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4F0Q
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MspJI Restriction Endonuclease - P21 Form
分子名称: MAGNESIUM ION, Restriction endonuclease
著者Horton, J.R, Mabuchi, M, Cohen-Karni, D, Zhang, X, Griggs, R, Samaranayake, M, Roberts, R.J, Zheng, Y, Cheng, X.
登録日2012-05-04
公開日2012-08-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.046 Å)
主引用文献Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
Nucleic Acids Res., 40, 2012
4F0P
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BU of 4f0p by Molmil
MspJI Restriction Endonuclease - P31 Form
分子名称: MAGNESIUM ION, Restriction endonuclease
著者Horton, J.R, Mabuchi, M, Cohen-Karni, D, Zhang, X, Griggs, R, Samaranayake, M, Roberts, R.J, Zheng, Y, Cheng, X.
登録日2012-05-04
公開日2012-08-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
Nucleic Acids Res., 40, 2012
9E6R
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BU of 9e6r by Molmil
BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma/leukemia 11A, DNA Strand I, ...
著者Horton, J.R, Cheng, X.
登録日2024-10-30
公開日2025-04-09
最終更新日2025-04-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs.
Nat Commun, 16, 2025
9E6S
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BU of 9e6s by Molmil
BCL11A ZF4-6 with K784T Mutation in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma/leukemia 11A, DNA Strand I, ...
著者Horton, J.R, Cheng, X.
登録日2024-10-30
公開日2025-04-09
最終更新日2025-04-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs.
Nat Commun, 16, 2025
9E6T
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BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGCCCA
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma/leukemia 11A, DNA Strand I, ...
著者Horton, J.R, Cheng, X.
登録日2024-10-30
公開日2025-04-09
最終更新日2025-04-30
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs.
Nat Commun, 16, 2025
8F8Y
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BU of 8f8y by Molmil
PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8F8Z
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PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
2NOG
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BU of 2nog by Molmil
SANT Domain Structure of Xenopus Remodeling Factor ISWI
分子名称: ISWI protein, MAGNESIUM ION
著者Horton, J.R, Cheng, X.
登録日2006-10-25
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI
Proteins, 67, 2007
1JQD
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Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine
分子名称: HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X.
登録日2001-08-06
公開日2002-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1JQE
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BU of 1jqe by Molmil
Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine
分子名称: Histamine N-Methyltransferase, QUINACRINE, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X.
登録日2001-08-06
公開日2002-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
3KV5
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BU of 3kv5 by Molmil
Structure of KIAA1718, human Jumonji demethylase, in complex with N-oxalylglycine
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV9
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BU of 3kv9 by Molmil
Structure of KIAA1718 Jumonji domain
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1D, OXYGEN MOLECULE
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KVB
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Structure of KIAA1718 Jumonji domain in complex with N-oxalylglycine
分子名称: JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV4
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Structure of PHF8 in complex with histone H3
分子名称: 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KVA
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BU of 3kva by Molmil
Structure of KIAA1718 Jumonji domain in complex with alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV6
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BU of 3kv6 by Molmil
Structure of KIAA1718, human Jumonji demethylase, in complex with alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ...
著者Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
登録日2009-11-29
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
6UKG
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BU of 6ukg by Molmil
HhaI endonuclease in Complex With DNA in space group P21 (pH 4.2)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKF
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HhaI endonuclease in Complex with DNA at 1 Angstrom Resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKI
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BU of 6uki by Molmil
HhaI endonuclease in Complex with DNA in space group P212121 (pH 6.0)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKE
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HhaI endonuclease in Complex with Iodine-Labelled DNA
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKH
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HhaI endonuclease in Complex with DNA in space group P41212 (pH 6.0)
分子名称: CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*G)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
4R28
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BU of 4r28 by Molmil
MspJI Restriction Endonuclease in Complex with 27-mer Oligonucleotide
分子名称: DNA (25-MER), DNA (26-MER), Restriction endonuclease
著者Horton, J.R, Cheng, X.
登録日2014-08-10
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.055 Å)
主引用文献Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
Nucleic Acids Res., 42, 2014
3PTR
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BU of 3ptr by Molmil
PHF2 Jumonji domain
分子名称: 1,2-ETHANEDIOL, PHD finger protein 2
著者Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X.
登録日2010-12-03
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
3PUA
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PHF2 Jumonji-NOG-Ni(II)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, N-OXALYLGLYCINE, ...
著者Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X.
登録日2010-12-03
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
3PVI
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D34G MUTANT OF PVUII ENDONUCLEASE COMPLEXED WITH COGNATE DNA SHOWS THAT ASP34 IS DIRECTLY INVOLVED IN DNA RECOGNITION AND INDIRECTLY INVOLVED IN CATALYSIS
分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII ENDONUCLEASE)
著者Horton, J.R, Cheng, X.
登録日1998-10-09
公開日1998-10-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis.
J.Mol.Biol., 284, 1998

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