1JQE
Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine
Summary for 1JQE
Entry DOI | 10.2210/pdb1jqe/pdb |
Related | 1JQD |
Descriptor | Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, QUINACRINE, ... (5 entities in total) |
Functional Keywords | classic methyltransferase fold, protein-substrate-cofactor complex, polymorphic variant, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P50135 |
Total number of polymer chains | 2 |
Total formula weight | 67858.92 |
Authors | Horton, J.R.,Sawada, K.,Nishibori, M.,Zhang, X.,Cheng, X. (deposition date: 2001-08-06, release date: 2002-08-06, Last modification date: 2024-04-03) |
Primary citation | Horton, J.R.,Sawada, K.,Nishibori, M.,Zhang, X.,Cheng, X. Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9:837-849, 2001 Cited by PubMed: 11566133DOI: 10.1016/S0969-2126(01)00643-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
Download full validation report