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3LWW
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BU of 3lww by Molmil
Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit
分子名称: Importin subunit beta-1, Snurportin-1
著者Bhardwaj, A, Cingolani, G.
登録日2010-02-24
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta.
Biochemistry, 49, 2010
4DKW
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BU of 4dkw by Molmil
Structure of P22 Large terminase nuclease domain
分子名称: Large terminase protein, MAGNESIUM ION, SULFATE ION
著者Roy, A, Cingolani, G.
登録日2012-02-04
公開日2012-06-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure of p22 headful packaging nuclease.
J.Biol.Chem., 287, 2012
4EI2
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BU of 4ei2 by Molmil
Crystal Structures of MthK RCK gating ring bound to Barium
分子名称: BARIUM ION, Calcium-gated potassium channel mthK
著者Smith, F.J, Cingolani, G, Rothberg, B.S.
登録日2012-04-04
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Crystal Structure of a Ba(2+)-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation.
Structure, 20, 2012
7JXT
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BU of 7jxt by Molmil
Ovine COX-1 in complex with the subtype-selective derivative 2a
分子名称: 2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ko, Y, Iaselli, M, Miciaccia, M, Friedrich, L, Schneider, G, Scilimati, A, Cingolani, G.
登録日2020-08-27
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design.
Adv Sci, 8, 2021
9BGN
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BU of 9bgn by Molmil
Pseudomonas phage DEV 5-fold vertex (major coat protein)
分子名称: gp77 major coat protein
著者Iglesias, S.M, Hou, C.F.D, Li, F, Cingolani, G.
登録日2024-04-19
公開日2024-09-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor.
Nat Commun, 15, 2024
9BGM
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BU of 9bgm by Molmil
Pseudomonas phage DEV neck and tail (portal, head-to-tail and tail tube proteins)
分子名称: gp75 tail tube, gp80 portal protein, gp83 head-to-tail
著者Iglesias, S.M, Hou, C.-F.D, Li, F, Cingolani, G.
登録日2024-04-19
公開日2024-09-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor.
Nat Commun, 15, 2024
9BGO
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BU of 9bgo by Molmil
Pseudomonas phage DEV gp72 ejection protein (pre-ejection conformation)
分子名称: gp72
著者Iglesias, S.M, Hou, C.F.D, Li, F, Cingolani, G.
登録日2024-04-19
公開日2024-09-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor.
Nat Commun, 15, 2024
3RWN
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BU of 3rwn by Molmil
Atomic structure of bacteriophage sf6 tail needle knob
分子名称: GLUTAMIC ACID, Gene 9 protein, PHOSPHATE ION
著者Bhardwaj, A, Cingolani, G.
登録日2011-05-09
公開日2011-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic structure of bacteriophage Sf6 tail needle knob.
J.Biol.Chem., 286, 2011
3TJ3
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BU of 3tj3 by Molmil
Structure of importin a5 bound to the N-terminus of Nup50
分子名称: Importin subunit alpha-1, Nuclear pore complex protein Nup50
著者Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G.
登録日2011-08-23
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.
J.Biol.Chem., 287, 2012
2Q5D
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BU of 2q5d by Molmil
Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form
分子名称: Importin beta-1 subunit, Snurportin-1
著者Mitrousis, G, Cingolani, G.
登録日2007-05-31
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
2P8Q
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BU of 2p8q by Molmil
Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain
分子名称: Importin beta-1 subunit, Snurportin-1
著者Mitrousis, G, Cingolani, G.
登録日2007-03-22
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
4HRF
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BU of 4hrf by Molmil
Atomic structure of DUSP26
分子名称: Dual specificity protein phosphatase 26
著者Lokareddy, R.K, Bhardwaj, A, Cingolani, G.
登録日2012-10-27
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
5JJ1
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BU of 5jj1 by Molmil
Structure of the Immature Procapsid Conformation of P22 Portal Protein
分子名称: Portal protein
著者Lokareddy, R.K, Cingolani, G.
登録日2016-04-22
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
5JJ3
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BU of 5jj3 by Molmil
Refined Structure of the Mature Virion Conformation of P22 Portal Protein
分子名称: Portal protein
著者Lokareddy, R.K, Sankhala, R.S, Cingolani, G.
登録日2016-04-22
公開日2017-02-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
3P9A
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BU of 3p9a by Molmil
An atomic view of the nonameric small terminase subunit of Bacteriophage P22
分子名称: DNA-packaging protein gp3
著者Bhardwaj, A, Roy, A, Cingolani, G.
登録日2010-10-17
公開日2012-05-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.755 Å)
主引用文献Small terminase couples viral DNA binding to genome-packaging ATPase activity.
Structure, 20, 2012
3Q5U
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BU of 3q5u by Molmil
A minimal NLS from human scramblase 4 complexed with importin alpha
分子名称: Importin subunit alpha-2, Phospholipid scramblase 4
著者Bhardwaj, A, Cingolani, G.
登録日2010-12-29
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1.
J.Biol.Chem., 286, 2011
4KEE
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BU of 4kee by Molmil
Crystal Structure of Cofilin Mutant (cof1-158p)
分子名称: Cofilin
著者Kish-Trier, E, Haarer, B, Cingolani, G, Amberg, D.C.
登録日2013-04-25
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.448 Å)
主引用文献Crystal Structure of Cofilin Mutant (cof1-158p)
To be Published
4K6B
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BU of 4k6b by Molmil
Atomic structure of bacteriophage HS1 tail needle knob
分子名称: GLUTAMIC ACID, HS1 knob domain, PHOSPHATE ION
著者Bhardwaj, A, Cingolani, G.
登録日2013-04-15
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.101 Å)
主引用文献The tip of the tail needle affects the rate of DNA delivery by bacteriophage p22.
Plos One, 8, 2013
5BU5
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BU of 5bu5 by Molmil
HK620 Tail Needle crystallized at pH 9 (crystal form I)
分子名称: CALCIUM ION, CHLORIDE ION, DNA stabilization protein
著者Bhardwaj, A, Cingolani, G.
登録日2015-06-03
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4R30
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BU of 4r30 by Molmil
Structure of human laforin dual specificity phosphatase domain
分子名称: BETA-MERCAPTOETHANOL, Laforin, SULFATE ION
著者Sankhala, R.S, Koksal, A.C, Cingolani, G.
登録日2014-08-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dimeric quaternary structure of human laforin.
J.Biol.Chem., 290, 2015
5BVZ
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BU of 5bvz by Molmil
HK620 Tail Needle crystallized at pH 9 (Crystal form II)
分子名称: CALCIUM ION, CHLORIDE ION, DNA stabilization protein
著者Bhardwaj, A, Cingolani, G.
登録日2015-06-05
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
5D5K
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BU of 5d5k by Molmil
Crystal Structure NLS from human PARP-2 complexed with Importin alpha delta IBB
分子名称: Importin subunit alpha-1, Poly [ADP-ribose] polymerase 2
著者Riccio, A.A, Cingolani, G, Pascal, J.M.
登録日2015-08-10
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage.
Nucleic Acids Res., 44, 2016
5BU8
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BU of 5bu8 by Molmil
HK620 Tail Needle crystallized at pH 7.5 and derivatized with Xenon
分子名称: CALCIUM ION, DNA stabilization protein, XENON
著者Sankhala, R.S, Cingolani, G.
登録日2015-06-03
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4UAF
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BU of 4uaf by Molmil
Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain
分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2
著者Pumroy, R.A, Cingolani, G.
登録日2014-08-08
公開日2015-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Structure, 23, 2015
7LF4
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BU of 7lf4 by Molmil
Structure of importin a3 bound to the p50- and p65-NLSs
分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022

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