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6CCF
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BU of 6ccf by Molmil
Crystal Structure of the Human CAMKK1A in complex with Hesperadin
分子名称: 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase kinase 1, N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE, ...
著者Santiago, A.S, Counago, R.M, dos Reis, C.V, Ramos, P.Z, Silva, P.N.B, Drewry, D, Elkins, J.M, Massirer, K.B, Arruda, P, Edwards, A.M, Structural Genomics Consortium (SGC)
登録日2018-02-07
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Human CAMKK1A in complex with Hesperadin
To be Published
6BQL
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BU of 6bql by Molmil
Crystal Structure of the Human CAMKK2B in complex with TAE-226
分子名称: 1,2-ETHANEDIOL, 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE, ACETATE ION, ...
著者Counago, R.M, de Souza, G.P, dos Reis, C.V, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC)
登録日2017-11-28
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Human CAMKK2B in complex with TAE-226
To Be Published
6CD6
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BU of 6cd6 by Molmil
Crystal Structure of the Human CAMKK1A in complex with GSK650394
分子名称: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 1
著者Santiago, A.S, Counago, R.M, Righetto, G.L, Ramos, P.Z, Silva, P.N.B, Drewry, D, Elkins, J.M, Massirer, K.B, Arruda, P, Edwards, A.M, Structural Genomics Consortium (SGC)
登録日2018-02-08
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human CAMKK1A in complex with GSK650394
To be Published
7RR0
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BU of 7rr0 by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 222
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ...
著者Pymm, P, Glukhova, A, Black, K.A, Tham, W.H.
登録日2021-08-08
公開日2021-10-06
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
8HRX
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BU of 8hrx by Molmil
Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
8HRY
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BU of 8hry by Molmil
Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex
分子名称: Fab heavy chain from antibody IgG clone number YN9016, Fab light chain from antibody IgG clone number YN9016, Large S protein (Fragment), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-12-16
公開日2024-01-17
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
8THI
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BU of 8thi by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THJ
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BU of 8thj by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8RQ4
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BU of 8rq4 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid
分子名称: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE
著者Mazza, T, Beis, K.
登録日2024-01-17
公開日2024-02-14
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RQ3
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BU of 8rq3 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
分子名称: ATP-binding cassette sub-family C member 2
著者Mazza, T, Beis, K.
登録日2024-01-17
公開日2024-02-14
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
7QHA
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BU of 7qha by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol
分子名称: Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ...
著者North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J.
登録日2021-12-11
公開日2022-12-21
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
7VAF
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BU of 7vaf by Molmil
Cryo-EM structure of Rat NTCP complexed with YN69202Fab
分子名称: Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter
著者Asami, J, Shimizu, T, Ohto, U.
登録日2021-08-29
公開日2022-05-25
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
7VAG
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BU of 7vag by Molmil
Cryo-EM structure of human NTCP complexed with YN69202Fab in the presence of myristoylated preS1 peptide
分子名称: Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter
著者Asami, J, Shimizu, T, Ohto, U.
登録日2021-08-29
公開日2022-05-25
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
7VAD
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BU of 7vad by Molmil
Cryo-EM structure of human NTCP complexed with YN69202Fab
分子名称: Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter
著者Asami, J, Shimizu, T, Ohto, U.
登録日2021-08-29
公開日2022-05-25
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
7VAE
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BU of 7vae by Molmil
Cryo-EM structure of bovine NTCP complexed with YN69202Fab
分子名称: Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Solute carrier family 10 (Sodium/bile acid cotransporter family), ...
著者Asami, J, Shimizu, T, Ohto, U.
登録日2021-08-29
公開日2022-05-25
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
3AI5
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BU of 3ai5 by Molmil
Crystal structure of yeast enhanced green fluorescent protein-ubiquitin fusion protein
分子名称: 1,2-ETHANEDIOL, yeast enhanced green fluorescent protein,Ubiquitin
著者Suzuki, N, Wakatsuki, S, Kawasaki, M.
登録日2010-05-10
公開日2010-09-29
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
7WSI
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BU of 7wsi by Molmil
Cryo-EM structure of human NTCP (wild-type) complexed with YN69202Fab
分子名称: Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter
著者Asami, J, Shimizu, T, Ohto, U.
登録日2022-01-29
公開日2022-05-25
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structure of the bile acid transporter and HBV receptor NTCP.
Nature, 606, 2022
3AI4
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BU of 3ai4 by Molmil
Crystal structure of yeast enhanced green fluorescent protein - mouse polymerase iota ubiquitin binding motif fusion protein
分子名称: SULFATE ION, yeast enhanced green fluorescent protein,DNA polymerase iota
著者Suzuki, N, Wakatsuki, S, Kawasaki, M.
登録日2010-05-10
公開日2010-09-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
8B01
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BU of 8b01 by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc
分子名称: DECANE, DOCOSANE, HEXANE, ...
著者Davies, J.S, North, R.A, Dobson, R.C.J.
登録日2022-09-06
公開日2023-03-15
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
7T3E
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BU of 7t3e by Molmil
Structure of the sialic acid bound Tripartite ATP-independent Periplasmic (TRAP) periplasmic component SiaP from Photobacterium profundum
分子名称: N-acetyl-beta-neuraminic acid, SULFATE ION, TRAP-type C4-dicarboxylate transport system, ...
著者Davies, J.S, Currie, M.J, North, R.A, Dobson, R.C.J.
登録日2021-12-07
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
4GKP
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BU of 4gkp by Molmil
Structure of the truncated neck and C-terminal motor homology domain of ViK1 from Candida glabrata
分子名称: Spindle pole body-associated protein VIK1
著者Duan, D, Allingham, J.S.
登録日2012-08-13
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
4GKQ
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BU of 4gkq by Molmil
Structure of the neck and C-terminal motor homology domain of ViK1 from Candida glabrata
分子名称: SPINDLE POLE BODY-ASSOCIATED PROTEIN VIK1
著者Duan, D, Allingham, J.S.
登録日2012-08-13
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
4GKR
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BU of 4gkr by Molmil
Structure of the C-terminal motor domain of Kar3 from Candida glabrata
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Duan, D, Allingham, J.S.
登録日2012-08-13
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
4YBQ
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BU of 4ybq by Molmil
Rat GLUT5 with Fv in the outward-open form
分子名称: Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ...
著者Nomura, N, Shimamura, T, Iwata, S.
登録日2015-02-19
公開日2015-10-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
7LX5
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BU of 7lx5 by Molmil
The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
分子名称: Spike glycoprotein, WNb 10, WNb 2
著者Pymm, P, Glukhova, A, Tham, W.-H.
登録日2021-03-03
公開日2021-05-05
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.
Proc.Natl.Acad.Sci.USA, 118, 2021

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件を2025-07-09に公開中

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