6CD6

Crystal Structure of the Human CAMKK1A in complex with GSK650394

Summary for 6CD6

Entry DOI	10.2210/pdb6cd6/pdb
Descriptor	Calcium/calmodulin-dependent protein kinase kinase 1, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	132482.45
Authors	Santiago, A.S.,Counago, R.M.,Righetto, G.L.,Ramos, P.Z.,Silva, P.N.B.,Drewry, D.,Elkins, J.M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Structural Genomics Consortium (SGC) (deposition date: 2018-02-08, release date: 2018-03-07, Last modification date: 2023-10-04)
Primary citation	Santiago, A.S.,Counago, R.M.,Righetto, G.L.,Ramos, P.Z.,Silva, P.N.B.,Drewry, D.,Elkins, J.M.,Massirer, K.B.,Arruda, P.,Edwards, A.M. Crystal Structure of the Human CAMKK1A in complex with GSK650394 To be Published,
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation