6CD6
Crystal Structure of the Human CAMKK1A in complex with GSK650394
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Calcium/calmodulin-dependent protein kinase kinase 1 | polymer | 290 | 32702.7 | 4 | UniProt (Q8N5S9) Pfam (PF00069) In PDB | Homo sapiens (Human) | CaMKK 1, CaM-kinase IV kinase, Calcium/calmodulin-dependent protein kinase kinase alpha, CaMKK alpha |
2 | A, B, C, D | 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | non-polymer | 382.5 | 4 | Chemie (DXV) | |||
3 | A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 124 - 411 (UniProt: Q8N5S9)
PDB | External Database | Details |
---|---|---|
Ser 122 | - | expression tag |
Met 123 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130810.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1671.6 | |
All* | Total formula weight | 132482.4 |