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4QXB
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BU of 4qxb by Molmil
crystal structure of histone demethylase KDM2A-H3K36ME3 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QWN
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BU of 4qwn by Molmil
Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-16
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QX8
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BU of 4qx8 by Molmil
Crystal structure of histone demethylase kdm2a-h3k36me3 complex with alpha-kg
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
6OP6
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BU of 6op6 by Molmil
Structure of VIM-20 in the reduced state
分子名称: Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION
著者Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
登録日2019-04-24
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
6OP7
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BU of 6op7 by Molmil
Structure of oxidized VIM-20
分子名称: ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION
著者Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
登録日2019-04-24
公開日2019-10-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
1T2L
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BU of 1t2l by Molmil
Three Crystal Structures of Human Coactosin-like Protein
分子名称: Coactosin-like protein
著者Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W.
登録日2004-04-22
公開日2004-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Coactosin-like Protein
J.Mol.Biol., 344, 2004
2XUE
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BU of 2xue by Molmil
CRYSTAL STRUCTURE OF JMJD3
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
著者Chung, C, Rowland, P, Mosley, J, Thomas, P.J.
登録日2010-10-19
公開日2011-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488, 2012
6J6M
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BU of 6j6m by Molmil
Co-crystal structure of BTK kinase domain with Zanubrutinib
分子名称: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK
著者Zhou, X, Hong, Y.
登録日2019-01-15
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
2O0F
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BU of 2o0f by Molmil
Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3
分子名称: Peptide chain release factor 3
著者Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H.
登録日2006-11-27
公開日2007-07-24
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (15.5 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
1RZ4
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BU of 1rz4 by Molmil
Crystal Structure of Human eIF3k
分子名称: Eukaryotic translation initiation factor 3 subunit 11, SULFATE ION
著者Wei, Z, Zhang, P, Zhou, Z, Gong, W.
登録日2003-12-23
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human eIF3k, the first structure of eIF3 subunits
J.Biol.Chem., 279, 2004
4EYU
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BU of 4eyu by Molmil
The free structure of the mouse C-terminal domain of KDM6B
分子名称: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Cheng, Z.J, Patel, D.J.
登録日2012-05-01
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
4EZ4
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BU of 4ez4 by Molmil
free KDM6B structure
分子名称: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Cheng, Z.J, Patel, D.J.
登録日2012-05-02
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
4EZH
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BU of 4ezh by Molmil
the crystal structure of KDM6B bound with H3K27me3 peptide
分子名称: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Cheng, Z.J, Patel, D.J.
登録日2012-05-02
公開日2012-08-08
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
4ASK
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BU of 4ask by Molmil
CRYSTAL STRUCTURE OF JMJD3 WITH GSK-J1
分子名称: 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, COBALT (II) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
著者Chung, C, Mosley, J, Liddle, J.
登録日2012-05-01
公開日2012-07-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488, 2012
4A3N
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BU of 4a3n by Molmil
Crystal Structure of HMG-BOX of Human SOX17
分子名称: TRANSCRIPTION FACTOR SOX-17, ZINC ION
著者Gao, N, Gao, H, Qian, H, Si, S, Xie, Y.
登録日2011-10-01
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
1YJX
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BU of 1yjx by Molmil
Crystal structure of human B type phosphoglycerate mutase
分子名称: CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1
著者Wang, Y, Wei, Z, Liu, L, Gong, W.
登録日2005-01-16
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human B-type phosphoglycerate mutase bound with citrate.
Biochem.Biophys.Res.Commun., 331, 2005
1YFK
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BU of 1yfk by Molmil
Crystal structure of human B type phosphoglycerate mutase
分子名称: CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1
著者Wang, Y, Wei, Z, Liu, L, Gong, W.
登録日2005-01-02
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human B-type phosphoglycerate mutase bound with citrate.
Biochem.Biophys.Res.Commun., 331, 2005
2KBE
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BU of 2kbe by Molmil
solution structure of amino-terminal domain of Dbp5p
分子名称: ATP-dependent RNA helicase DBP5
著者Fan, J.S, Zhang, J, Yang, D.
登録日2008-11-27
公開日2009-10-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
2KBF
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BU of 2kbf by Molmil
solution structure of carboxyl-terminal domain of Dbp5p
分子名称: ATP-dependent RNA helicase DBP5
著者Fan, J.S, Zhang, J, Yang, D.
登録日2008-11-28
公開日2009-10-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
2A9J
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BU of 2a9j by Molmil
Human bisphosphoglycerate mutase complexed with 3-phosphoglycerate (17 days)
分子名称: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase
著者Wang, Y, Gong, W.
登録日2005-07-11
公開日2006-10-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
4XT9
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BU of 4xt9 by Molmil
RORgamma (263-509) complexed with GSK2435341A and SRC2
分子名称: LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ...
著者Wang, Y, Ma, Y.
登録日2015-01-23
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
2F90
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BU of 2f90 by Molmil
Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4-
分子名称: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION
著者Wang, Y, Liu, L, Wei, Z, Gong, W.
登録日2005-12-05
公開日2006-10-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
5K7X
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BU of 5k7x by Molmil
Fully ligated Adenylosuccinate Synthetase from Pyrococcus horikoshii OT3 with GTP, IMP and Hadacidin
分子名称: Adenylosuccinate synthetase, GUANOSINE-5'-TRIPHOSPHATE, HADACIDIN, ...
著者Xie, Y, Cheng, Z.
登録日2016-05-27
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Crystal structure of hypothetical adenylosuccinate synthetase, PH0438 from Pyrococcus horikoshii OT3
To Be Published
5CM4
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BU of 5cm4 by Molmil
Crystal structure of human Frizzled 4 Cysteine-Rich Domain (CRD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4
著者Ke, J, Parker, N, Gu, X, Zhang, C, Melcher, K, Xu, H.E.
登録日2015-07-16
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
2H4Z
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BU of 2h4z by Molmil
Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate
分子名称: (2R)-2,3-diphosphoglyceric acid, Bisphosphoglycerate mutase
著者Wang, Y, Gong, W.
登録日2006-05-25
公開日2006-10-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase.
J.Biol.Chem., 281, 2006

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