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3U9G
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BU of 3u9g by Molmil
Crystal structure of the Zinc finger antiviral protein
分子名称: ZINC ION, Zinc finger CCCH-type antiviral protein 1
著者Chen, S, Xu, Y, Zhang, K, Wang, X, Sun, J, Gao, G, Liu, Y.
登録日2011-10-18
公開日2012-03-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
4OS7
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BU of 4os7 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK607 (bicyclic)
分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4OS5
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BU of 4os5 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK603 (bicyclic 2)
分子名称: SULFATE ION, Urokinase-type plasminogen activator, bicyclic peptide UK603 (bicyclic 2)
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4OS1
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BU of 4os1 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK601 (bicyclic 1)
分子名称: ACETATE ION, SULFATE ION, Urokinase-type plasminogen activator, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4OS6
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BU of 4os6 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK604 (bicyclic 2)
分子名称: ACETATE ION, SULFATE ION, Urokinase-type plasminogen activator, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4OS4
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BU of 4os4 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK603 (bicyclic 1)
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4MNX
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BU of 4mnx by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK811
分子名称: 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, GLYCEROL, SULFATE ION, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2013-09-11
公開日2014-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Peptide ligands stabilized by small molecules.
Angew.Chem.Int.Ed.Engl., 53, 2014
4OS2
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BU of 4os2 by Molmil
Crystal structure of urokinase-type plasminogen activator (uPA) complexed with bicyclic peptide UK602 (bicyclic 1)
分子名称: ACETATE ION, SULFATE ION, Urokinase-type plasminogen activator, ...
著者Chen, S, Pojer, F, Heinis, C.
登録日2014-02-12
公開日2014-09-24
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
5DAG
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BU of 5dag by Molmil
Crystal structure of PZP domain of human AF10 protein
分子名称: Protein AF-10, ZINC ION
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
分子名称: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
6NQ3
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BU of 6nq3 by Molmil
Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex
分子名称: Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ...
著者Chen, S, Jiao, L, Liu, X.
登録日2019-01-19
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
Mol.Cell, 77, 2020
3ZDP
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BU of 3zdp by Molmil
R416A Monomeric nucleoprotein of influenza A virus
分子名称: NUCLEOCAPSID PROTEIN, POTASSIUM ION
著者Chenavas, S, Ruigrok, R.W.H, Crepin, T.
登録日2012-11-29
公開日2013-04-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Monomeric Nucleoprotein of Influenza a Virus.
Plos Pathog., 9, 2013
6J20
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BU of 6j20 by Molmil
Crystal structure of the human NK1 substance P receptor
分子名称: 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin
著者Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q.
登録日2018-12-30
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
6J21
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BU of 6j21 by Molmil
Crystal structure of the human NK1 substance P receptor
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin
著者Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q.
登録日2018-12-30
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
3O5Z
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BU of 3o5z by Molmil
Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphatidylinositol 3-kinase regulatory subunit beta
著者Chen, S, Xiao, Y, Ponnusamy, R, Tan, J, Lei, J, Hilgenfeld, R.
登録日2010-07-28
公開日2011-08-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit
Acta Crystallogr.,Sect.F, 67, 2011
3P38
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BU of 3p38 by Molmil
Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1
著者Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P31
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BU of 3p31 by Molmil
Crystal structure of the NS1 effector domain from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1, THIOCYANATE ION
著者Chen, S, Xiao, Y.B, Ponnusamy, R, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P39
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BU of 3p39 by Molmil
Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1
著者Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
7DHY
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BU of 7dhy by Molmil
Arsenic-bound p53 DNA-binding domain mutant G245S
分子名称: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
著者Chen, S, Lu, M.
登録日2020-11-18
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
7DHZ
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BU of 7dhz by Molmil
Arsenic-bound p53 DNA-binding domain mutant R249S
分子名称: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
著者Chen, S, Lu, M.
登録日2020-11-18
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
1EJD
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BU of 1ejd by Molmil
Crystal structure of unliganded mura (type1)
分子名称: CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE
著者Eschenburg, S, Schonbrunn, E.
登録日2000-03-02
公開日2000-10-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1EJC
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BU of 1ejc by Molmil
Crystal structure of unliganded mura (type2)
分子名称: GLYCEROL, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE
著者Eschenburg, S, Schonbrunn, E.
登録日2000-03-02
公開日2000-10-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1I6U
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BU of 1i6u by Molmil
RNA-PROTEIN INTERACTIONS: THE CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN S8/RRNA COMPLEX FROM METHANOCOCCUS JANNASCHII
分子名称: 16S RRNA FRAGMENT, 30S RIBOSOMAL PROTEIN S8P, SULFATE ION
著者Tishchenko, S, Nikulin, A, Fomenkova, N, Nevskaya, N, Nikonov, O, Dumas, P, Moine, H, Ehresmann, B, Ehresmann, C, Piendl, W, Lamzin, V, Garber, M, Nikonov, S.
登録日2001-03-05
公開日2001-08-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii.
J.Mol.Biol., 311, 2001
1BH6
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BU of 1bh6 by Molmil
SUBTILISIN DY IN COMPLEX WITH THE SYNTHETIC INHIBITOR N-BENZYLOXYCARBONYL-ALA-PRO-PHE-CHLOROMETHYL KETONE
分子名称: CALCIUM ION, N-BENZYLOXYCARBONYL-ALA-PRO-3-AMINO-4-PHENYL-BUTAN-2-OL, SODIUM ION, ...
著者Eschenburg, S, Genov, N, Wilson, K.S, Betzel, C.
登録日1998-06-15
公開日1998-11-04
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg.
Eur.J.Biochem., 257, 1998
1R8O
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BU of 1r8o by Molmil
Crystal structure of an unusual Kunitz-type trypsin inhibitor from Copaifera langsdorffii seeds
分子名称: Kunitz trypsin inhibitor
著者Krauchenco, S, Nagem, R.A.P, da Silva, J.A, Marangoni, S, Polikarpov, I.
登録日2003-10-27
公開日2004-05-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Three-dimensional structure of an unusual Kunitz (STI) type trypsin inhibitor from Copaifera langsdorffii.
Biochimie, 86, 2004

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