7ZBG
| Human Topoisomerase II Beta ATPase ADP | 分子名称: | 4-[(2S,3R)-3-[3,5-bis(oxidanylidene)piperazin-1-ium-1-yl]butan-2-yl]piperazin-4-ium-2,6-dione, ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase 2-beta, ... | 著者 | Ling, E.M, Basle, A, Cowell, I.G, Blower, T.R, Austin, C.A. | 登録日 | 2022-03-23 | 公開日 | 2022-05-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193. Structure, 30, 2022
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7Z3V
| Escherichia coli periplasmic phytase AppA D304E mutant, complex with myo-inositol hexakissulfate | 分子名称: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, POTASSIUM ION | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | 登録日 | 2022-03-02 | 公開日 | 2022-06-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. Int J Mol Sci, 23, 2022
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7PCY
| THE CRYSTAL STRUCTURE OF PLASTOCYANIN FROM A GREEN ALGA, ENTEROMORPHA PROLIFERA | 分子名称: | COPPER (II) ION, PLASTOCYANIN | 著者 | Collyer, C.A, Guss, J.M, Freeman, H.C. | 登録日 | 1989-09-22 | 公開日 | 1990-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of plastocyanin from a green alga, Enteromorpha prolifera. J.Mol.Biol., 211, 1990
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7Z2A
| P. berghei kinesin-8B motor domain in no nucleotide state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-10-19 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7Z2C
| P. falciparum kinesin-8B motor domain in no nucleotide bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-10-19 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7Z2B
| P. berghei kinesin-8B motor domain in AMPPNP state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-11-16 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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1WA3
| Mechanism of the Class I KDPG aldolase | 分子名称: | 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE, PYRUVIC ACID, SULFATE ION | 著者 | Fullerton, S.W.B, Griffiths, J.S, Merkel, A.B, Wymer, N.J, Hutchins, M.J, Fierke, C.A, Toone, E.J, Naismith, J.H. | 登録日 | 2004-10-22 | 公開日 | 2005-01-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of the Class I Kdpg Aldolase. Bioorg.Med.Chem., 14, 2006
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1W9L
| Myosin II Dictyostelium discoideum motor domain S456E bound with MgADP-AlF4 | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. | 登録日 | 2004-10-13 | 公開日 | 2006-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Function Analysis of Myosin II Backdoor Mutants To be Published
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1W9J
| Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-AlF4 | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. | 登録日 | 2004-10-13 | 公開日 | 2006-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-Function Analysis of Myosin II Backdoor Mutants To be Published
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1W9K
| Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. | 登録日 | 2004-10-13 | 公開日 | 2006-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure-Function Analysis of Myosin II Backdoor Mutants To be Published
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1W9I
| Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. | 登録日 | 2004-10-13 | 公開日 | 2006-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-Function Analysis of Myosin II Backdoor Mutants To be Published
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1WCI
| Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-BUTYL-THIAMIN, ... | 著者 | Machius, M, Wynn, R.M, Chuang, J.L, Tomchick, D.R, Brautigam, C.A, Chuang, D.T. | 登録日 | 2004-11-16 | 公開日 | 2006-02-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure, 14, 2006
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1WKX
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1WNH
| Crystal structure of mouse Latexin (tissue carboxypeptidase inhibitor) | 分子名称: | Latexin | 著者 | Aagaard, A, Listwan, P, Cowieson, N, Huber, T, Ravasi, T, Wells, C.A, Flanagan, J.U, Hume, D.A, Kobe, B, Martin, J.L. | 登録日 | 2004-08-04 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | An Inflammatory Role for the Mammalian Carboxypeptidase Inhibitor Latexin: Relationship to Cystatins and the Tumor Suppressor TIG1 Structure, 13, 2005
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2FNS
| Crystal structure of wild-type inactive (D25N) HIV-1 protease complexed with wild-type HIV-1 NC-p1 substrate. | 分子名称: | ACETATE ION, NC-P1 SUBSTRATE PEPTIDE, PHOSPHATE ION, ... | 著者 | Prabu-Jeyabalan, M, Nalivaika, E.A, Schiffer, C.A. | 登録日 | 2006-01-11 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate. J.Virol., 80, 2006
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2FNT
| Crystal structure of a drug-resistant (V82A) inactive (D25N) HIV-1 protease complexed with AP2V variant of HIV-1 NC-p1 substrate. | 分子名称: | ACETATE ION, NC-p1 substrate PEPTIDE, PHOSPHATE ION, ... | 著者 | Prabu-Jeyabaln, M, Nalivaika, E.A, Schiffer, C.A. | 登録日 | 2006-01-11 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate. J.Virol., 80, 2006
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3UMS
| Crystal structure of the G202A mutant of human G-alpha-i1 | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Lambert, N.A, Johnston, C.A, Cappell, S.D, Kuravi, S, Kimple, A.J, Willard, F.S, Siderovski, D.P. | 登録日 | 2011-11-14 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | 主引用文献 | Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity Proc.Natl.Acad.Sci.USA, 2012
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3KDF
| X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression | 分子名称: | 1,2-ETHANEDIOL, Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Fox, B.G, Makino, S.-I, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-10-22 | 公開日 | 2009-12-01 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression To be Published
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2QI3
| Crystal structure of protease inhibitor, MIT-2-AD94 in complex with wild type HIV-1 protease | 分子名称: | (2S)-N-[(1S,2R)-3-{(1,3-BENZOTHIAZOL-6-YLSULFONYL)[(2S)-2-METHYLBUTYL]AMINO}-1-BENZYL-2-HYDROXYPROPYL]-2-HYDROXY-3-METHYLBUTANAMIDE, PHOSPHATE ION, Protease | 著者 | Nalam, M.N.L, Schiffer, C.A. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
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2QI1
| Crystal structure of protease inhibitor, MIT-1-KK81 in complex with wild type HIV-1 protease | 分子名称: | N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(3-METHOXYPHENYL)SULFONYL](2-THIENYLMETHYL)AMINO}PROPYL]-3,4-DIHYDROXYBENZAMIDE, PHOSPHATE ION, Protease | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
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2R2X
| Ricin A-chain (recombinant) complex with Urea | 分子名称: | Ricin A chain, SULFATE ION, UREA | 著者 | Carra, J.H, McHugh, C.A, Mulligan, S, Machiesky, L.M, Soares, A.S, Millard, C.B. | 登録日 | 2007-08-28 | 公開日 | 2007-11-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site. Bmc Struct.Biol., 7, 2007
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2QHY
| Crystal Structure of protease inhibitor, MIT-1-AC86 in complex with wild type HIV-1 protease | 分子名称: | ACETATE ION, N~2~-ACETYL-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{(2-THIENYLMETHYL)[(2,4,5-TRIFLUOROPHENYL)SULFONYL]AMINO}PROPYL]-L-ALANINAMIDE, PHOSPHATE ION, ... | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
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2QHZ
| Crystal structure of protease inhibitor, MIT-1-AC87 in complex with wild type HIV-1 protease | 分子名称: | (2E)-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{(2-THIENYLMETHYL)[(2,4,5-TRIFLUOROPHENYL)SULFONYL]AMINO}PROPYL]-4,4,4-TRIFLUORO-3-METHYLBUT-2-ENAMIDE, PHOSPHATE ION, Protease | 著者 | Schiffer, C.A, Nalam, M.N.L. | 登録日 | 2007-07-03 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
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3KUY
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2QH4
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