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8UQ8
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BU of 8uq8 by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 2-residue linker
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ...
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQD
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BU of 8uqd by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (condition 2. RING not modeled in density)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.893 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8UQC
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BU of 8uqc by Molmil
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 2)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8V9U
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BU of 8v9u by Molmil
Solution NMR structure of human DNMT1 N-terminal alpha-helical domain
分子名称: DNA (cytosine-5)-methyltransferase 1
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-12-09
公開日2024-02-28
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献Identification of a conserved alpha-helical domain at the N terminus of human DNA methyltransferase 1.
J.Biol.Chem., 300, 2024
8SMX
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BU of 8smx by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SMW
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BU of 8smw by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN6
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BU of 8sn6 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 4)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN7
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BU of 8sn7 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 5)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN4
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BU of 8sn4 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SMY
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BU of 8smy by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN2
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BU of 8sn2 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN5
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BU of 8sn5 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SNA
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BU of 8sna by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SMZ
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BU of 8smz by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (Class 4)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN3
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BU of 8sn3 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN8
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BU of 8sn8 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN9
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BU of 8sn9 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN0
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BU of 8sn0 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 5)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
8SN1
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BU of 8sn1 by Molmil
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6)
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ...
著者Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G.
登録日2023-04-26
公開日2024-01-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
2IG0
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BU of 2ig0 by Molmil
Structure of 53BP1/methylated histone peptide complex
分子名称: Dimethylated Histone H4-K20 peptide, SULFATE ION, Tumor suppressor p53-binding protein 1
著者Mer, G.
登録日2006-09-22
公開日2007-01-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair.
Cell(Cambridge,Mass.), 127, 2006
3FSS
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BU of 3fss by Molmil
Structure of the tandem PH domains of Rtt106
分子名称: GLYCEROL, Histone chaperone RTT106, MALONIC ACID
著者Su, D, Thompson, J.R, Mer, G.
登録日2009-01-11
公開日2009-12-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.432 Å)
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
2LVM
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BU of 2lvm by Molmil
Solution structure of human 53BP1 tandem Tudor domains in complex with a histone H4K20me2 peptide
分子名称: Histone H4, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M, Mer, G.
登録日2012-07-07
公開日2012-12-12
最終更新日2013-04-03
実験手法SOLUTION NMR
主引用文献Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.
Nat.Struct.Mol.Biol., 20, 2013
3SZM
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BU of 3szm by Molmil
STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE
分子名称: Histone H2A.x, Microcephalin
著者Singh, N, Thompson, J.R, Mer, G.
登録日2011-07-19
公開日2011-11-30
最終更新日2012-09-19
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TW1
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BU of 3tw1 by Molmil
Structure of Rtt106-AHN
分子名称: GLYCEROL, Histone chaperone RTT106, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE
著者Su, D, Thompson, J.R, Mer, G.
登録日2011-09-21
公開日2012-02-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
3TVV
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BU of 3tvv by Molmil
Structure of the tandem PH domains of Rtt106 (residues 68-315)
分子名称: Histone chaperone RTT106
著者Su, D, Thompson, J.R, Mer, G.
登録日2011-09-20
公開日2012-02-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.589 Å)
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012

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件を2024-07-03に公開中

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