3UTZ
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![BU of 3utz by Molmil](/molmil-images/mine/3utz) | Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential | 分子名称: | Metalloproteinase, heavy chain, light chain, ... | 著者 | Sela-Passwell, N, Kikkeri, R, Dym, O, Rozenberg, H, Margalit, R, Arad-Yellin, R, Eisenstein, M, Brenner, O, Shoham, T, Danon, T, Shanzer, A, Sagi, I, Israel Structural Proteomics Center (ISPC) | 登録日 | 2011-11-27 | 公開日 | 2011-12-14 | 最終更新日 | 2017-03-15 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. NAT.MED. (N.Y.), 18, 2012
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6RV5
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![BU of 6rv5 by Molmil](/molmil-images/mine/6rv5) | X-ray structure of the levansucrase from Erwinia tasmaniensis in complex with levanbiose | 分子名称: | GLYCEROL, Levansucrase (Beta-D-fructofuranosyl transferase), ZINC ION, ... | 著者 | Polsinelli, I, Caliandro, R, Demitri, N, Benini, S. | 登録日 | 2019-05-31 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | The Structure of Sucrose-Soaked Levansucrase Crystals fromErwinia tasmaniensisreveals a Binding Pocket for Levanbiose. Int J Mol Sci, 21, 2019
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6MRC
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![BU of 6mrc by Molmil](/molmil-images/mine/6mrc) | ADP-bound human mitochondrial Hsp60-Hsp10 football complex | 分子名称: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | 著者 | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | 登録日 | 2018-10-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin. Nat Commun, 11, 2020
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6MRD
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![BU of 6mrd by Molmil](/molmil-images/mine/6mrd) | ADP-bound human mitochondrial Hsp60-Hsp10 half-football complex | 分子名称: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | 著者 | Gomez-Llorente, Y, Jebara, F, Patra, M, Malik, R, Nissemblat, S, Azem, A, Hirsch, J.A, Ubarretxena-Belandia, I. | 登録日 | 2018-10-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin. Nat Commun, 11, 2020
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8FYG
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![BU of 8fyg by Molmil](/molmil-images/mine/8fyg) | Crystal structure of Hyaluronate lyase A from Cutibacterium acnes | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Hyaluronate lyase | 著者 | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | 登録日 | 2023-01-26 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8FNX
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![BU of 8fnx by Molmil](/molmil-images/mine/8fnx) | Crystal structure of Hyaluronate lyase B from Cutibacterium acnes | 分子名称: | GLYCEROL, Hyaluronate lyase, PHOSPHATE ION | 著者 | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | 登録日 | 2022-12-28 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8G0O
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![BU of 8g0o by Molmil](/molmil-images/mine/8g0o) | Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes | 分子名称: | Hyaluronate lyase | 著者 | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | 登録日 | 2023-02-01 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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3N30
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![BU of 3n30 by Molmil](/molmil-images/mine/3n30) | Crystal Structure of cubic Zn3-hUb (human ubiquitin) adduct | 分子名称: | Ubiquitin, ZINC ION | 著者 | Siliqi, D, Caliandro, R, Arnesano, F, Natile, G, Falini, G, Fermani, S, Belviso, B.D. | 登録日 | 2010-05-19 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystallographic analysis of metal-ion binding to human ubiquitin. Chemistry, 17, 2011
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3N32
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![BU of 3n32 by Molmil](/molmil-images/mine/3n32) | The crystal structure of human Ubiquitin adduct with Zeise's salt | 分子名称: | PLATINUM (II) ION, Ubiquitin | 著者 | Siliqi, D, Caliandro, R, Falini, G, Fermani, S, Natile, G, Arnesano, F, Belviso, B.D. | 登録日 | 2010-05-19 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | 主引用文献 | Crystallographic analysis of metal-ion binding to human ubiquitin. Chemistry, 17, 2011
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5H6Z
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![BU of 5h6z by Molmil](/molmil-images/mine/5h6z) | Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe | 分子名称: | AMMONIUM ION, DI(HYDROXYETHYL)ETHER, SET domain-containing protein 7, ... | 著者 | Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E. | 登録日 | 2016-11-15 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis. Structure, 27, 2019
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6EO8
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![BU of 6eo8 by Molmil](/molmil-images/mine/6eo8) | Crystal structure of thrombin in complex with a novel glucose-conjugated potent inhibitor | 分子名称: | DIMETHYL SULFOXIDE, Hirudin variant-2, N-(2-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methoxy}-6-[3-(beta-D-glucopyranosyloxy)propoxy]phenyl)-1-(propan-2-yl)piperidine-4-carboxamide, ... | 著者 | Belviso, B.D, Caliandro, R, Aresta, B.M, De Candia, M, Altomare, C.D. | 登録日 | 2017-10-09 | 公開日 | 2017-12-13 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | How a beta-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties. J. Med. Chem., 57, 2014
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6EO9
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![BU of 6eo9 by Molmil](/molmil-images/mine/6eo9) | Crystal structure of thrombin in complex with a novel glucose-conjugated potent inhibitor | 分子名称: | DIMETHYL SULFOXIDE, Hirudin variant-2, N-(2-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methoxy}-6-{3-[(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy]propoxy}phenyl)-1-(propan-2-yl)piperidine-4-carboxamide, ... | 著者 | Belviso, B.D, Caliandro, R, Aresta, B.M, De Candia, M, Altomare, C.D. | 登録日 | 2017-10-09 | 公開日 | 2017-12-13 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | How a beta-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties. J. Med. Chem., 57, 2014
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6FRW
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![BU of 6frw by Molmil](/molmil-images/mine/6frw) | X-ray structure of the levansucrase from Erwinia tasmaniensis | 分子名称: | GLYCEROL, Levansucrase (Beta-D-fructofuranosyl transferase), ZINC ION | 著者 | Polsinelli, I, Salomone-Stagni, M, Caliandro, R, Demitri, N, Benini, S. | 登録日 | 2018-02-16 | 公開日 | 2019-02-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Comparison of the Levansucrase from the epiphyte Erwinia tasmaniensis vs its homologue from the phytopathogen Erwinia amylovora. Int. J. Biol. Macromol., 127, 2019
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4GJH
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![BU of 4gjh by Molmil](/molmil-images/mine/4gjh) | Crystal Structure of the TRAF domain of TRAF5 | 分子名称: | TNF receptor-associated factor 5 | 著者 | Zhang, P, Reichardt, A, Liang, H, Wang, Y, Cheng, D, Aliyari, R, Cheng, G, Liu, Y. | 登録日 | 2012-08-09 | 公開日 | 2012-11-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | 主引用文献 | Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5 Sci.Signal., 5, 2012
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4G9L
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![BU of 4g9l by Molmil](/molmil-images/mine/4g9l) | Structure of MMP3 complexed with NNGH inhibitor. | 分子名称: | CALCIUM ION, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, Stromelysin-1, ... | 著者 | Belviso, B.D, Arnesano, F, Calderone, V, Caliandro, R, Natile, G, Siliqi, D. | 登録日 | 2012-07-24 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structure of matrix metalloproteinase-3 with a platinum-based inhibitor. Chem.Commun.(Camb.), 49, 2013
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6U4B
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![BU of 6u4b by Molmil](/molmil-images/mine/6u4b) | WbbM bifunctional glycosytransferase apo structure | 分子名称: | MAGNESIUM ION, WbbM protein | 著者 | Kimber, M.S, Mallette, E, Kamski-Hennekam, E.R, Gitalis, R. | 登録日 | 2019-08-25 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family. Nat.Chem.Biol., 16, 2020
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5WW0
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![BU of 5ww0 by Molmil](/molmil-images/mine/5ww0) | Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe | 分子名称: | SET domain-containing protein 7, SULFATE ION | 著者 | Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E. | 登録日 | 2016-12-30 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis. Structure, 27, 2019
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8FBZ
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![BU of 8fbz by Molmil](/molmil-images/mine/8fbz) | Crystal Structure of apo human Glutathione Synthetase Y270E | 分子名称: | GLYCEROL, Glutathione synthetase, SULFATE ION | 著者 | Stanford, S.M, Santelli, E, Sankaran, B, Murali, R, Bottini, N. | 登録日 | 2022-11-30 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy. Sci Adv, 10, 2024
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7BB1
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![BU of 7bb1 by Molmil](/molmil-images/mine/7bb1) | Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Glutamic acid 2:1 | 分子名称: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | 著者 | Belviso, B.D, Caliandro, R, Carrozzini, B. | 登録日 | 2020-12-16 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
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7B9J
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![BU of 7b9j by Molmil](/molmil-images/mine/7b9j) | Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Urea 1:2 | 分子名称: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | 著者 | Belviso, B.D, Caliandro, R, Carrozzini, B. | 登録日 | 2020-12-14 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
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7BAZ
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![BU of 7baz by Molmil](/molmil-images/mine/7baz) | Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Glycerol 1:2 | 分子名称: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | 著者 | Belviso, B.D, Caliandro, R, Carrozzini, B. | 登録日 | 2020-12-16 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
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4P7E
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![BU of 4p7e by Molmil](/molmil-images/mine/4p7e) | Triazolopyridine compounds as selective JAK1 inhibitors: from hit identification to GLPG0634 | 分子名称: | N-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, Tyrosine-protein kinase JAK2 | 著者 | Menet, C.C.J, Fletcher, S, Van Lommen, G, Geney, R, Blanc, J, Smits, K, Jouannigot, N, van der Aar, E.M, Clement-Lacroix, P, Lepescheux, L, Galien, R, Vayssiere, B, Nelles, L, Christophe, T, Brys, R, Uhring, M, Ciesielski, F, Van Rompaey, L. | 登録日 | 2014-03-27 | 公開日 | 2014-11-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J.Med.Chem., 57, 2014
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2Y3M
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![BU of 2y3m by Molmil](/molmil-images/mine/2y3m) | Structure of the extra-membranous domain of the secretin HofQ from Actinobacillus actinomycetemcomitans | 分子名称: | FORMIC ACID, GLYCEROL, PROTEIN TRANSPORT PROTEIN HOFQ | 著者 | Tarry, M, Jaaskelainen, M, Tuominen, H, Ihalin, R, Hogbom, M. | 登録日 | 2010-12-21 | 公開日 | 2011-04-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Extra-Membranous Domains of the Competence Protein Hofq Show DNA Binding, Flexibility and a Shared Fold with Type I Kh Domains. J.Mol.Biol., 409, 2011
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7ZC3
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![BU of 7zc3 by Molmil](/molmil-images/mine/7zc3) | Crystal structure of human copper chaperone Atox1 bound to zinc ion by CxxC motif | 分子名称: | Copper transport protein ATOX1, SULFATE ION, ZINC ION | 著者 | Mangini, V, Belviso, B.D, Arnesano, F, Caliandro, R. | 登録日 | 2022-03-25 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion. Biomolecules, 12, 2022
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4JA1
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![BU of 4ja1 by Molmil](/molmil-images/mine/4ja1) | Structure of MMP3 complexed with a platinum-based inhibitor | 分子名称: | CALCIUM ION, CHLORIDE ION, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ... | 著者 | Belviso, B.D, Arnesano, F, Calderone, V, Caliandro, R, Natile, G, Siliqi, D. | 登録日 | 2013-02-18 | 公開日 | 2013-02-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of matrix metalloproteinase-3 with a platinum-based inhibitor. Chem.Commun.(Camb.), 49, 2013
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