8FBZ

Crystal Structure of apo human Glutathione Synthetase Y270E

Summary for 8FBZ

Entry DOI	10.2210/pdb8fbz/pdb
Descriptor	Glutathione synthetase, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	glutathione synthesis atpase, biosynthetic protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	106052.14
Authors	Stanford, S.M.,Santelli, E.,Sankaran, B.,Murali, R.,Bottini, N. (deposition date: 2022-11-30, release date: 2024-05-08)
Primary citation	Stanford, S.M.,Nguyen, T.P.,Chang, J.,Zhao, Z.,Hackman, G.L.,Santelli, E.,Sanders, C.M.,Katiki, M.,Dondossola, E.,Brauer, B.L.,Diaz, M.A.,Zhan, Y.,Ramsey, S.H.,Watson, P.A.,Sankaran, B.,Paindelli, C.,Parietti, V.,Mikos, A.G.,Lodi, A.,Bagrodia, A.,Elliott, A.,McKay, R.R.,Murali, R.,Tiziani, S.,Kettenbach, A.N.,Bottini, N. Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy. Sci Adv, 10:eadg7887-eadg7887, 2024 Cited by PubMed: 38295166 DOI: 10.1126/sciadv.adg7887 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation