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Crystal structure of a H2N2 influenza virus hemagglutinin, avian like
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Xu, R, Wilson, I.A.
登録日	2009-11-26
公開日	2010-01-19
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010

3KU5

Crystal structure of a H2N2 influenza virus hemagglutinin, human like
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Xu, R, Wilson, I.A.
登録日	2009-11-26
公開日	2010-01-19
最終更新日	2021-10-13
実験手法	X-RAY DIFFRACTION (1.73 Å)
主引用文献	Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010

3KU6

Crystal structure of a H2N2 influenza virus hemagglutinin, 226L/228G
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Xu, R, Wilson, I.A.
登録日	2009-11-26
公開日	2010-01-19
最終更新日	2021-10-13
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010

2FX9

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
分子名称:	Fab 4E10, Fragment of HIV glycoprotein gp41
著者	Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日	2006-02-03
公開日	2006-12-19
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J.Mol.Biol., 365, 2007

2FX8

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
分子名称:	Fab 4E10, Fragment of HIV glycoprotein (GP41)
著者	Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日	2006-02-03
公開日	2006-12-19
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J.Mol.Biol., 365, 2007

2FX7

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
分子名称:	Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
著者	Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日	2006-02-03
公開日	2006-12-19
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.76 Å)
主引用文献	Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J.Mol.Biol., 365, 2007

2QGC

Human transthyretin (TTR) complexed with 2-(3,5-Dimethyl-4-hydroxyphenyl)benzoxazole
分子名称:	4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL, Transthyretin
著者	Connelly, S, Wilson, I.A.
登録日	2007-06-28
公開日	2008-02-05
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. J.Med.Chem., 51, 2008

2QSC

Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide
分子名称:	CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ...
著者	Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A.
登録日	2007-07-30
公開日	2008-01-15
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J.Mol.Biol., 375, 2008

2R6Q

Crystal Structure of BclA-island Construct
分子名称:	BclA protein
著者	Han, B.W, Herrin, B.R, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
登録日	2007-09-06
公開日	2009-03-10
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.43 Å)
主引用文献	Crystal structure of BclA-island Construct To be Published

2R9U

Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain
分子名称:	Variable lymphocyte receptor
著者	Han, B.W, Herrin, B.R, Choe, J, Cooper, M.D, Wilson, I.A.
登録日	2007-09-13
公開日	2009-03-10
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain. To be Published

6DID

HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者	Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B.
登録日	2018-05-23
公開日	2018-09-05
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.71 Å)
主引用文献	Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018

6DCW

Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
分子名称:	Heavy chain of CBTAU27.1 Fab, Light chain of CBTAU27.1 Fab, tau peptide
著者	Zhu, X, Zhang, H, Wilson, I.A.
登録日	2018-05-08
公開日	2018-06-06
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018

5XRS

Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin in complex with LSTc
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ...
著者	Zhang, H, Wilson, I.A.
登録日	2017-06-09
公開日	2018-07-25
最終更新日	2022-10-12
実験手法	X-RAY DIFFRACTION (2.907 Å)
主引用文献	A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018

5XRT

Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Zhang, H, Wilson, I.A.
登録日	2017-06-09
公開日	2018-07-25
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.15 Å)
主引用文献	A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018

6E3H

Crystal structure of S9-3-37 bound to H5 influenza hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者	Wu, N.C, Wilson, I.A.
登録日	2018-07-14
公開日	2018-09-26
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	The D3-9 gene segment encodes for recurring and adaptable binding motifs in broadly neutralizing antibodies to influenza virus Cell Host Microbe, 2018

5YL9

1.86 Angstrom crystal structure of human Coronavirus 229E fusion core
分子名称:	Spike glycoprotein
著者	Yang, B, Yan, L, Meng, B, WIlson, I.A.
登録日	2017-10-17
公開日	2018-09-26
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.861 Å)
主引用文献	Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 angstrom resolution Acta Crystallogr D Struct Biol, 74, 2018

5ZIA

Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide
分子名称:	Heavy chain of CBTAU-24.1 antibody, Light chain (kappa) of CBTAU-24.1 antibody, phosphorylated tau peptide
著者	Zhang, H, Wilson, I.A.
登録日	2018-03-14
公開日	2018-10-31
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.603 Å)
主引用文献	Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody. Structure, 26, 2018

5ZUV

Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称:	CHLORIDE ION, Spike glycoprotein,Spike glycoprotein,inhibitor EK1
著者	Yan, L, Yang, B, Wilson, I.A.
登録日	2018-05-08
公開日	2019-04-10
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.21 Å)
主引用文献	A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019

5ZVM

Crystal Structure of the Human Coronavirus SARS HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称:	Spike glycoprotein, pan-CoV inhibitory peptide EK1
著者	Yan, L, Yang, B, Wilson, I.A.
登録日	2018-05-11
公開日	2019-04-10
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019

5ZVK

Crystal Structure of the Human Coronavirus MERS HR1 motif in complex with pan-CoVs inhibitor EK1
分子名称:	Human Coronavirus MERS HR1 motif, pan-CoV inhibitory peptide EK1
著者	Yan, L, Yang, B, Wilson, I.A.
登録日	2018-05-11
公開日	2019-04-10
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (3.31 Å)
主引用文献	A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019

5ZV3

Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide
分子名称:	Heavy chain of antibody CBTAU28.1, Light chain (kappa) of antibody CBTAU28.1, Peptide from Microtubule-associated protein tau
著者	Zhang, H, Wilson, I.A.
登録日	2018-05-09
公開日	2018-06-20
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.093 Å)
主引用文献	A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018

7RA7

Crystal structure of rabbit anti-HIV Fab 11A
分子名称:	11A Fab heavy chain, 11A Fab light chain, PENTAETHYLENE GLYCOL, ...
著者	Oyen, D, Wilson, I.A.
登録日	2021-06-30
公開日	2022-07-06
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions To Be Published

2VAB

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
分子名称:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, SENDAI VIRUS NUCLEOPROTEIN
著者	Fremont, D.H, Wilson, I.A.
登録日	1994-11-01
公開日	1996-06-20
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

2VAA

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
著者	Fremont, D.H, Wilson, I.A.
登録日	1994-11-01
公開日	1996-06-20
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

2B1G

Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
分子名称:	7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE, Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, ...
著者	Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A.
登録日	2005-09-15
公開日	2006-11-21
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase. J.Biol.Chem., 282, 2007

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