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9GHG
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BU of 9ghg by Molmil
Staphylococcus aureus FusB bound to the small subunit of the S. aureus 70S ribosome (FusB-Sa70S:SSU)
分子名称: 1,4-DIAMINOBUTANE, 23S rRNA, 30S ribosomal protein S11, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2024-08-15
公開日2025-03-26
最終更新日2025-04-30
実験手法ELECTRON MICROSCOPY (2.22 Å)
主引用文献Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis.
Nat Commun, 16, 2025
9GHE
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BU of 9ghe by Molmil
Staphylococcus aureus FusB bound to the small subunit of the Escherichia coli 70S ribosome (FusB-70S:SSU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2024-08-15
公開日2025-03-26
最終更新日2025-04-30
実験手法ELECTRON MICROSCOPY (1.87 Å)
主引用文献Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis.
Nat Commun, 16, 2025
9GHA
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BU of 9gha by Molmil
Fusidic acid-locked Escherichia coli 70S ribosome with Staphylococcus aureus EF-G and a tRNA in pe/E chimeric state (CHI)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2024-08-15
公開日2025-03-26
最終更新日2025-04-30
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis.
Nat Commun, 16, 2025
9GHB
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BU of 9ghb by Molmil
Fusidic acid-locked Escherichia coli 70S ribosome with Staphylococcus aureus EF-G in post-translocational state (POST)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2024-08-15
公開日2025-03-26
最終更新日2025-04-30
実験手法ELECTRON MICROSCOPY (2.21 Å)
主引用文献Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis.
Nat Commun, 16, 2025
9H0L
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BU of 9h0l by Molmil
70S ribosome with cognate tRNASer3 bound to A-site AGC codon
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Akbar, S, Larsson, D.S.D, Selmer, M.
登録日2024-10-08
公開日2025-05-28
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Doublet decoding of tRNA Ser3 demonstrates plasticity of ribosomal decoding center.
Nat Commun, 16, 2025
9GXX
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BU of 9gxx by Molmil
70S ribosome with doublet-decoding tRNASer3 bound to A-site GCA codon
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Krishnaswamy, S, Larsson, D.S.D, Selmer, M.
登録日2024-10-01
公開日2025-05-28
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Doublet decoding of tRNA Ser3 demonstrates plasticity of ribosomal decoding center.
Nat Commun, 16, 2025
2XEX
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BU of 2xex by Molmil
crystal structure of Staphylococcus aureus elongation factor G
分子名称: CHLORIDE ION, ELONGATION FACTOR G, POTASSIUM ION
著者Chen, Y, Koripella, R.K, Sanyal, S, Selmer, M.
登録日2010-05-19
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Staphylococcus Aureus Elongation Factor G - Structure and Analysis of a Target for Fusidic Acid.
FEBS J., 277, 2010
2UXC
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BU of 2uxc by Molmil
Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA UCGU in the context of the Thermus thermophilus 30S subunit.
分子名称: 16S RIBOSOMAL RNA, A-SITE MESSENGER RNA FRAGMENT CGGG, ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON ACGA, ...
著者Dunham, C.M, Selmer, M, Phelps, S.S, Kelley, A.C, Suzuki, T, Joseph, S, Ramakrishnan, V.
登録日2007-03-28
公開日2007-05-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Trnas with an Expanded Anticodon Loop in the Decoding Center of the 30S Ribosomal Subunit.
RNA, 13, 2007
2X7Z
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BU of 2x7z by Molmil
Crystal Structure of the SAP97 PDZ2 I342W C378A mutant protein domain
分子名称: AMMONIUM ION, DISKS LARGE HOMOLOG 1, IMIDAZOLE
著者Haq, S.R, Jurgens, M.C, Chi, C.N, Elfstrom, L, Koh, C.S, Selmer, M, Gianni, S, Jemth, P.
登録日2010-03-04
公開日2010-03-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Plastic Energy Landscape of Protein Folding: A Triangular Folding Mechanism with an Equilibrium Intermediate for a Small Protein Domain.
J.Biol.Chem., 285, 2010
6Y88
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BU of 6y88 by Molmil
IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP
分子名称: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, CITRIC ACID, GLYCEROL, ...
著者Soderholm, A, Selmer, M.
登録日2020-03-03
公開日2020-09-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.09983444 Å)
主引用文献Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa : Decarboxylation is not essential for indole formation.
J.Biol.Chem., 295, 2020
6XXQ
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BU of 6xxq by Molmil
Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with ATP and spectinomycin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Kanchugal P, S, Selmer, M.
登録日2020-01-28
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis.
Antimicrob.Agents Chemother., 64, 2020
6XZ0
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BU of 6xz0 by Molmil
Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with spectinomycin
分子名称: SPECTINOMYCIN, Streptomycin 3''-adenylyltransferase
著者Kanchugal P, S, Selmer, M.
登録日2020-01-31
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis.
Antimicrob.Agents Chemother., 64, 2020
5ABT
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BU of 5abt by Molmil
S.enterica HisA mutant D7N, G102A, V106M, D176A
分子名称: 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
著者Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2015-08-08
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
5AC6
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BU of 5ac6 by Molmil
S.enterica HisA mutant D10G, dup13-15, Q24L, G102A
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SULFATE ION
著者Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2015-08-12
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.993 Å)
主引用文献The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
5AB3
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BU of 5ab3 by Molmil
S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE
著者Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2015-07-31
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AC8
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BU of 5ac8 by Molmil
S. enterica HisA with mutations D10G, dup13-15, G102A
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SULFATE ION
著者Newton, M, Guo, X, Soderholm, A, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2015-08-12
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AC7
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BU of 5ac7 by Molmil
S. enterica HisA with mutations D7N, D10G, dup13-15
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, GLYCEROL, SODIUM ION, ...
著者Newton, M, Guo, X, Soderholm, A, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2015-08-12
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AHI
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BU of 5ahi by Molmil
Crystal structure of salmonalla enterica HisA mutant D7N with ProFAR
分子名称: 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, CHLORIDE ION, GLYCEROL, ...
著者Soderholm, A, Guo, X, Newton, M.S, Evans, G.B, Nasvall, J, Patrick, W.M, Selmer, M.
登録日2015-02-06
公開日2016-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structure and Mechanism of Hisa from Salmonella Enterica
To be Published
5AHE
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BU of 5ahe by Molmil
Crystal structure of Salmonella enterica HisA
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Soderholm, A, Guo, X, Newton, M.S, Evans, G.B, Nasvall, J, Patrick, W.M, Selmer, M.
登録日2015-02-05
公開日2015-09-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5AHF
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BU of 5ahf by Molmil
Crystal structure of Salmonella enterica HisA D7N with ProFAR
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, GLYCEROL, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
著者Soderholm, A, Guo, X, Newton, M.S, Evans, G.B, Nasvall, J, Patrick, W.M, Selmer, M.
登録日2015-02-05
公開日2015-09-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5A5W
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BU of 5a5w by Molmil
Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
著者Soderholm, A, Guo, X, Newton, M.S, Evans, G.B, Nasvall, J, Patrick, W.M, Selmer, M.
登録日2015-06-23
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
3ZZU
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BU of 3zzu by Molmil
Crystal structure of Staphylococcus aureus elongation factor G with mutations M16I and F88L
分子名称: ELONGATION FACTOR G
著者Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
登録日2011-09-05
公開日2012-07-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Mechanism of Elongation Factor-G Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
3ZZ0
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BU of 3zz0 by Molmil
Crystal structure of ribosomal elongation factor (EF)-G from Staphylococcus aureus with a fusidic acid hyper-sensitivity mutation M16I
分子名称: Elongation factor G
著者Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
登録日2011-08-30
公開日2012-07-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus.
J. Biol. Chem., 287, 2012
4AUK
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BU of 4auk by Molmil
Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M.
登録日2012-05-18
公開日2012-08-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna.
Nucleic Acids Res., 40, 2012
4BLU
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BU of 4blu by Molmil
Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Punekar, A.S, Liljeruhm, J, Shepherd, T.R, Forster, A.C, Selmer, M.
登録日2013-05-04
公開日2013-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Nucleic Acids Res., 41, 2013

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件を2025-07-09に公開中

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