6Y88
IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP
Summary for 6Y88
Entry DOI | 10.2210/pdb6y88/pdb |
Descriptor | Indole-3-glycerol phosphate synthase, Indole-3-glycerol phosphate synthase,Indole-3-glycerol phosphate synthase, 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, ... (7 entities in total) |
Functional Keywords | tryptophan biosynthesis, carboxylyase, ba8-barrel, indole synthesis, lyase |
Biological source | Pseudomonas aeruginosa More |
Total number of polymer chains | 8 |
Total formula weight | 253506.26 |
Authors | Soderholm, A.,Selmer, M. (deposition date: 2020-03-03, release date: 2020-09-23, Last modification date: 2024-01-24) |
Primary citation | Soderholm, A.,Newton, M.S.,Patrick, W.M.,Selmer, M. Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa : Decarboxylation is not essential for indole formation. J.Biol.Chem., 295:15948-15956, 2020 Cited by PubMed: 32928960DOI: 10.1074/jbc.RA120.014936 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09983451737 Å) |
Structure validation
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