6Y88

IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP

Summary for 6Y88

• Entry DOI: 10.2210/pdb6y88/pdb
• Descriptor: Indole-3-glycerol phosphate synthase, Indole-3-glycerol phosphate synthase,Indole-3-glycerol phosphate synthase, 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, ... (7 entities in total)
• Functional Keywords: tryptophan biosynthesis, carboxylyase, ba8-barrel, indole synthesis, lyase
• Biological source: Pseudomonas aeruginosa; More
• Total number of polymer chains: 8
• Total formula weight: 253506.26

Authors

Soderholm, A.,Selmer, M. (deposition date: 2020-03-03, release date: 2020-09-23, Last modification date: 2024-01-24)

• Primary citation: Soderholm, A.,Newton, M.S.,Patrick, W.M.,Selmer, M.; Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa : Decarboxylation is not essential for indole formation.; J.Biol.Chem., 295:15948-15956, 2020; PubMed: 32928960; DOI: 10.1074/jbc.RA120.014936

Experimental method

X-RAY DIFFRACTION (2.09983451737 Å)