5AHI

Crystal structure of salmonalla enterica HisA mutant D7N with ProFAR

Summary for 5AHI

Related5AHE 5AHF
Descriptor1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, GLYCEROL, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, ... (6 entities in total)
Functional Keywordsisomerase, hisa, histidine biosynthesis
Biological sourceSALMONELLA ENTERICA
Cellular locationCytoplasm P10372
Total number of polymer chains1
Total molecular weight27930.79
Authors
Soderholm, A.,Guo, X.,Newton, M.S.,Evans, G.B.,Nasvall, J.,Patrick, W.M.,Selmer, M. (deposition date: 2015-02-06, release date: 2016-03-02)
Primary citation
Soderholm, A.,Guo, X.,Newton, M.S.,Evans, G.B.,Nasvall, J.,Patrick, W.M.,Selmer, M.
Structure and Mechanism of Hisa from Salmonella Enterica
To be Published,
Experimental method
X-RAY DIFFRACTION (1.999 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240600.5%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5ahi
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Molmil generated image of 5ahi
rotated about x axis by 90°
Molmil generated image of 5ahi
rotated about y axis by 90°