7CRQ
| NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode) | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | 登録日 | 2020-08-14 | 公開日 | 2020-10-21 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
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7CY6
| Crystal Structure of CMD1 in complex with 5mC-DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), FE (II) ION, ... | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | 登録日 | 2020-09-03 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7CY7
| Crystal Structure of CMD1 in complex with DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(P*CP*GP*CP*GP*CP*GP*GP*GP*A)-3'), FE (II) ION, ... | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | 登録日 | 2020-09-03 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7CY5
| Crystal Structure of CMD1 in complex with vitamin C | 分子名称: | ASCORBIC ACID, CITRIC ACID, FE (III) ION, ... | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | 登録日 | 2020-09-03 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7CY8
| Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C | 分子名称: | 1,2-ETHANEDIOL, ASCORBIC ACID, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), ... | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | 登録日 | 2020-09-03 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7CY4
| Crystal Structure of CMD1 in apo form | 分子名称: | CITRIC ACID, FE (III) ION, Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | 登録日 | 2020-09-03 | 公開日 | 2020-12-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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3UDC
| Crystal structure of a membrane protein | 分子名称: | Small-conductance mechanosensitive channel, C-terminal peptide from Small-conductance mechanosensitive channel | 著者 | Li, W, Ge, J, Yang, M. | 登録日 | 2011-10-28 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.355 Å) | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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4U85
| Human Pin1 with cysteine sulfinic acid 113 | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
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4U86
| Human Pin1 with cysteine sulfonic acid 113 | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
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4U84
| Human Pin1 with S-hydroxyl-cysteine 113 | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
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6V9T
| Tudor domain of TDRD3 in complex with a small molecule | 分子名称: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Tudor domain-containing protein 3, UNKNOWN ATOM OR ION | 著者 | Li, W, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-12-16 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.154 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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3EP2
| Model of Phe-tRNA(Phe) in the ribosomal pre-accommodated state revealed by cryo-EM | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | 著者 | Frank, J, Li, W, Agirrezabala, X. | 登録日 | 2008-09-29 | 公開日 | 2008-12-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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4G6H
| Crystal structure of NDH with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.262 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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2Z9Q
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4G6G
| Crystal structure of NDH with TRT | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, MAGNESIUM ION, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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4G74
| Crystal structure of NDH with Quinone | 分子名称: | 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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4G73
| Crystal structure of NDH with NADH and Quinone | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Li, W, Feng, Y, Ge, J, Yang, M. | 登録日 | 2012-07-19 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.522 Å) | 主引用文献 | Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature, 491, 2012
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1JT8
| ARCHAEAL INITIATION FACTOR-1A, AIF-1A | 分子名称: | PROBABLE TRANSLATION INITIATION FACTOR 1A | 著者 | Hoffman, D.W, Li, W. | 登録日 | 2001-08-20 | 公開日 | 2001-09-05 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics of translation initiation factor aIF-1A from the archaeon Methanococcus jannaschii determined by NMR spectroscopy Protein Sci., 10, 2001
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4OD5
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4OD4
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3EQ4
| Model of tRNA(Leu)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | 著者 | Frank, J, Li, W, Agirrezabala, X. | 登録日 | 2008-09-30 | 公開日 | 2008-12-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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3EQ3
| Model of tRNA(Trp)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | 著者 | Frank, J, Li, W, Agirrezabala, X. | 登録日 | 2008-09-30 | 公開日 | 2008-12-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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3SWH
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4DY0
| Crystal structure of native protease nexin-1 with heparin | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, GLYCEROL, Glia-derived nexin, ... | 著者 | Huntington, J.A, Li, W. | 登録日 | 2012-02-28 | 公開日 | 2012-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120, 2012
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4DY7
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