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7T51
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Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in molybdate-bound form
分子名称: AMMONIUM ION, GLYCEROL, MOLYBDATE ION, ...
著者Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B.
登録日2021-12-11
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
7T5A
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Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in tungstate-bound form
分子名称: AMMONIUM ION, Molybdate-binding periplasmic protein ModA, TUNGSTATE(VI)ION
著者Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B.
登録日2021-12-11
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
7UWG
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The crystal structure of the TIR domain-containing protein from Acinetobacter baumannii (AbTir)
分子名称: HEXAETHYLENE GLYCOL, Molecular chaperone Tir, SULFATE ION
著者Manik, M.K, Nanson, J.D, Ve, T, Kobe, B.
登録日2022-05-03
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Science, 377, 2022
7UXU
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CryoEM structure of the TIR domain from AbTir in complex with 3AD
分子名称: Molecular chaperone Tir, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(8-azanylisoquinolin-2-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
著者Li, S, Nanson, J.D, Manik, M.K, Gu, W, Landsberg, M.J, Ve, T, Kobe, B.
登録日2022-05-06
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Science, 377, 2022
1IQ1
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CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX
分子名称: IMPORTIN ALPHA-2 SUBUNIT
著者Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B.
登録日2001-05-28
公開日2001-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
3ND2
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Structure of Yeast Importin-beta (Kap95p)
分子名称: Importin subunit beta-1
著者Forwood, J.K, Kobe, B.
登録日2010-06-06
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
3OZI
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Crystal structure of the TIR domain from the flax disease resistance protein L6
分子名称: COBALT (II) ION, L6tr
著者Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B.
登録日2010-09-25
公開日2011-04-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation.
Cell Host Microbe, 9, 2011
6VZB
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Crystal structure of cytochrome P450 NasF5053 S284A-V288A mutant variant from Streptomyces sp. NRRL F-5053 in the cyclo-L-Trp-L-Pro-bound state
分子名称: (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
著者Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B.
登録日2020-02-28
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines.
Nat Commun, 11, 2020
6VZA
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Crystal structure of cytochrome P450 NasF5053 Q65I-A86G mutant variant from Streptomyces sp. NRRL F-5053 in the cyclo-L-Trp-L-Pro-bound state
分子名称: (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, CHLORIDE ION, ...
著者Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B.
登録日2020-02-28
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines.
Nat Commun, 11, 2020
6VXV
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Crystal structure of cyclo-L-Trp-L-Pro-bound cytochrome P450 NasF5053 from Streptomyces sp. NRRL F-5053
分子名称: (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B.
登録日2020-02-24
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines.
Nat Commun, 11, 2020
6W0S
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Crystal structure of substrate free cytochrome P450 NasF5053 from Streptomyces sp. NRRL F-5053
分子名称: BROMIDE ION, CHLORIDE ION, GLYCEROL, ...
著者Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B.
登録日2020-03-02
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines.
Nat Commun, 11, 2020
7RTC
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Crystal structure of the ARM domain from Drosophila SARM1 in complex with NaMN
分子名称: NAD(+) hydrolase sarm1, NICOTINATE MONONUCLEOTIDE
著者Gu, W, Ve, T, Kobe, B.
登録日2021-08-13
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection.
Exp Neurol, 345, 2021
7RTS
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Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 without the AE interface
分子名称: Disease resistance protein RUN1, SULFATE ION
著者Burdett, H, Kobe, B.
登録日2021-08-15
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
7RX1
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BU of 7rx1 by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1
分子名称: Disease resistance protein RUN1, SULFATE ION
著者Burdett, H, Kobe, B.
登録日2021-08-21
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
7S2Z
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Crystal structure of the E100A mutant TIR domain from the grapevine disease resistance protein RUN1 bound to NAD
分子名称: Disease resistance protein RUN1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Burdett, H, Kobe, B.
登録日2021-09-04
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
3SPS
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Crystal Structure of Apo-Hexameric Acyl-CoA Thioesterase
分子名称: Acyl-CoA hydrolase
著者Forwood, J.K, Marfori, M, Kobe, B.
登録日2011-07-03
公開日2011-08-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-Induced Conformational Changes within a Hexameric Acyl-CoA Thioesterase
To be Published
1EJY
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MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, NUCLEOPLASMIN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-05
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EJL
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MOUSE IMPORTIN ALPHA-SV40 LARGE T ANTIGEN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, SV40 LARGE T ANTIGEN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-03
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
5D8C
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Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to promoter DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*AP*AP*CP*TP*CP*TP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*TP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3'), MerR family regulator protein
著者Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B.
登録日2015-08-17
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
5D90
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Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to promoter DNA
分子名称: MerR family regulator protein
著者Counago, R.M, Chang, C.W, Kobe, B.
登録日2015-08-18
公開日2016-06-29
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
5E01
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Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA
分子名称: 5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3', Uncharacterized HTH-type transcriptional regulator HI_0186
著者Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B.
登録日2015-09-26
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
7L6W
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SFX structure of the MyD88 TIR domain higher-order assembly
分子名称: Myeloid differentiation primary response protein MyD88
著者Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Flueckiger, L, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Stacey, K.J, Darmanin, C, Kobe, B, Xu, H, Ve, T.
登録日2020-12-24
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
5TEB
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Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1
分子名称: Recognition of Peronospora parasitica 1
著者Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B.
登録日2016-09-20
公開日2017-02-01
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V4L
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Cryptococcus neoformans adenylosuccinate lyase
分子名称: Adenylosuccinate lyase
著者Chitty, J, Williams, S.J, Kobe, B, Fraser, J.A.
登録日2017-03-09
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J. Biol. Chem., 292, 2017
5U5R
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Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a PMS2 NLS Peptide
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Mismatch repair endonuclease PMS2
著者Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R.
登録日2016-12-07
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Biochimie, 146, 2018

221051

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